公开(公告)号：EP4397661A1

公开(公告)日：2024-07-10

申请号：EP22863588.4

申请日：2022-09-01

申请人： Xizang Haisco Pharmaceutical Co., Ltd.

发明人： ZHANG, Chen ,  LIAO, Yuting ,  LU, Yonghua ,  ZHAO, Junbin ,  ZOU, Sijia ,  YU, Yan ,  TANG, Pingming ,  GAO, Qiu ,  CHENG, Xinfan ,  YE, Fei ,  LI, Yao ,  NI, Jia ,  YAN, Pangke

IPC分类号： C07D487/04 ,  C07K5/083 ,  A61K31/5377 ,  A61P35/00

CPC分类号： C07D487/04 ,  A61K31/5377 ,  A61P35/00 ,  C07K5/0804

摘要： A compound of general formula (I) or a stereoisomer, a deuterated compound, a solvate, a prodrug, a metabolite, a pharmaceutically acceptable salt, or a co-crystal thereof, an intermediate thereof, and a use thereof in Bcl-2 family proteinsrelated diseases such as cancer. B-L-K (I)