公开(公告)号：EP1025847A1

公开(公告)日：2000-08-09

申请号：EP98940584.0

申请日：1998-08-26

申请人： YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. ,  Nissan Chemical Industries, Ltd.

发明人： EGI, Yasuhiro, Yoshitomi Pharm. Industries, Ltd ,  KIDO, Hideaki, Yoshitomi Pharm. Industries, Ltd ,  HAYASHI, Kazutaka, Yoshitomi Pharm.Industries, Ltd ,  KUBO, Yoshiji, Yoshitomi Pharm. Industries Ltd. ,  NAKAMURA, Norifumi, Yoshitomi Pharm.Industries Ltd

IPC分类号： A61K31/50

CPC分类号： C07D401/12

摘要： An angiogenesis promoter and angiogenesis potentiator containing a pyridazinone compound of the formula (I)
wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof, as an active ingredient. The pyridazinone compound (I) and a pharmacologically acceptable salt thereof in the present invention promote angiogenesis and potentiate the angiogenic effect of a drug having such effect, and are useful as an angiogenesis promoter and angiogenesis potentiator.

摘要翻译： 含有式（I）的哒嗪酮化合物的血管生成促进剂和血管生成增强剂，其中每个符号如说明书中所定义，或其药理学上可接受的盐作为活性成分。 本发明中的哒嗪酮化合物（I）及其药理学上可接受的盐促进血管生成并增强具有这种作用的药物的血管生成作用，并且可用作血管生成促进剂和血管生成增强剂。