专利检索 ap:("Yoshitomi Pharmaceutical Industries, Ltd.") AND inv:"Kobayashi, Kaoru, The Green Cross Corporation" 第 1 页

1.

发明授权
Method for sterilizing recombinant human serum albumin pharmaceutical preparation 无效
标题翻译：一种用于含白蛋白的人重组血清药物组合物的灭菌过程

公开(公告)号：EP0650736B1

公开(公告)日：2000-06-28

申请号：EP94116937.7

申请日：1994-10-26

申请人： Yoshitomi Pharmaceutical Industries, Ltd.

发明人： Ohya, Tomoshi, The Green Cross Corporation , Ohda, Toyoo, The Green Cross Corporation , Kuwae, Shinobu, The Green Cross Corporation , Tomomitsu, Kenji, The Green Cross Corporation , Kobayashi, Kaoru, The Green Cross Corporation , Ohmura, Takao, The Green Cross Corporation

IPC分类号： A61L2/04

CPC分类号： C07K14/765 , A61K38/38 , A61L2/0023 , A61L2/04 , C12N7/04 , Y02A50/473

摘要： A recombinant human serum albumin (rHSA) pharmaceutical preparation is sterilized by subjecting a pharmaceutical preparation of rHSA obtained by gene manipulation techniques packed in a container in an administration unit to heat treatment at 50 to 80 DEG C for 30 minutes or more. By the disclosed method, rHSA having high safety can be provided since microorganisms contaminated in rHSA pharmaceutical preparations die as a result of the sterilization method of the present invention.