专利检索 ap:("ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI" OR "BANYU PHARMACEUTICAL CO., LTD.") AND inv:"Sasaki, Fujinori CO-OP Shincho No. 203" 第 1 页

1.

发明公开
N-Methylphenylserine alkyl ester derivatives and uses thereof 失效
标题翻译： N-甲基苯基乙醇烷基酯衍生物及其用途

公开(公告)号：EP0218440A3

公开(公告)日：1988-01-13

申请号：EP86307456

申请日：1986-09-29

申请人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI , BANYU PHARMACEUTICAL CO., LTD.

发明人： Umezawa, Hamao , Nagatsu, Toshiharu , Takeuchi, Tomio , Sasaki, Fujinori CO-OP Shincho No. 203 , Morishima, Hajime , Sawasaki, Yoshio , Takezawa, Hiroshi

IPC分类号： C07C101/32 , A61K31/195 , C07C101/72

CPC分类号： A61K31/195

摘要： As new compounds N-methyl-3-(3,4-dihydroxyphenyl)serine alkyl esters. These are effective as a-adrenergic and β-adrenergic agenta to stimulate the a-adrenergic and β-adrenergic functions of the central nervous system of mammalian animals. Such compounds can be useful for therapeutic treatment of disorders as invoked by reduced biological activities or functions of the a-and/or β-adrenergic neurons. N-methyl-L-threo-3-(3,4-dihydroxyphenyl)serine (C 1 - Cs) alkyl esters are preferred amongst the new compounds of this invention.