公开(公告)号：EP2892902A1

公开(公告)日：2015-07-15

申请号：EP13762671.9

申请日：2013-09-04

申请人： Zoetis LLC

发明人： SHEEHAN, Susan M. K. ,  VAILLANCOURT, Valerie A.

IPC分类号： C07D491/10 ,  A61K31/397 ,  A61P33/00

CPC分类号： C07D491/107

摘要： The invention recites spirocyclic derivatives of Formula (V.1) or (V.2), stereoisomers thereof, veterinary acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide for an animal. The variables A, B, V, Z, Y, W
1 , W
2, W
3 , R
1a , R
1b , R
1c , R
2 , R
3 , R
4 , n, and "---" are as described herein.

公开(公告)号：EP2705044A1

公开(公告)日：2014-03-12

申请号：EP12720640.7

申请日：2012-04-19

申请人： ZOETIS LLC

发明人： DUCLOS, Brian A. ,  ELLSWORTH, Edmund L. ,  EWIN, Richard A. ,  JOHNSON, Paul D. ,  JOHNSON, Timothy A. ,  KYNE, Graham M. ,  SHEEHAN, Susan M. K. ,  VAIRAGOUNDAR, Rajendran

IPC分类号： C07D501/24 ,  A61K31/546 ,  A61P31/04

CPC分类号： C07D501/24

摘要： The present invention provides novel cephalosporin derivatives of formula (I), their analogues, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of these compounds.