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公开(公告)号：EP0669834A1
公开(公告)日：1995-09-06
申请号：EP94900578.0
申请日：1993-11-09
CPC分类号： A61K38/45
摘要： The present invention provides methods for inhibiting delayed bleeding of wounds and post-operative hemorrhage through the topical application of factor XIII. The methods may be used at surgical sites, including intracranial sites, and in coagulophatic patients.
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公开(公告)号：EP0624095B1
公开(公告)日：1998-09-16
申请号：EP93902779.3
申请日：1992-12-28
申请人： ZYMOGENETICS, INC.
CPC分类号： A61K38/45 , A61K38/55 , A61K2300/00
摘要： Blood loss in a patient undergoing surgery, particularly thoracic or abdominal surgery, is reduced by administration of factor XIII. The factor XIII may be administered in combination with aprotinin.
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公开(公告)号：EP0624095B2
公开(公告)日：2005-07-20
申请号：EP93902779.3
申请日：1992-12-28
申请人： ZYMOGENETICS, INC.
CPC分类号： A61K38/45 , A61K38/55 , A61K2300/00
摘要： Blood loss in a patient undergoing surgery, particularly thoracic or abdominal surgery, is reduced by administration of factor XIII. The factor XIII may be administered in combination with aprotinin.
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公开(公告)号：EP0669834B1
公开(公告)日：1999-09-08
申请号：EP94900578.9
申请日：1993-11-09
IPC分类号： A61K38/45
CPC分类号： A61K38/45
摘要： The present invention provides methods for inhibiting delayed bleeding of wounds and post-operative hemorrhage through the topical application of factor XIII. The methods may be used at surgical sites, including intracranial sites, and in coagulophatic patients.
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公开(公告)号：EP0624095A1
公开(公告)日：1994-11-17
申请号：EP93902779.0
申请日：1992-12-28
申请人： ZYMOGENETICS, INC.
CPC分类号： A61K38/45 , A61K38/55 , A61K2300/00
摘要： La perte de sang chez un patient subissant une intervention chirurgicale, notamment du thorax ou de l'abdomen, est réduite en administrant le facteur XIII. Le facteur XIII peut être administré avec l'aprotinine.
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