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公开(公告)号:EP2686347B1
公开(公告)日:2018-05-02
申请号:EP12710486.7
申请日:2012-03-16
申请人: argenx BVBA
发明人: SILENCE, Karen , ULRICHTS, Peter , DE HAARD, Johannes Joseph Wilhelmus , DREIER, Torsten , SAUNDERS, Michael John Scott , WAJANT, Harald , GABRIELS, Sofie Maria Elvire , MOSHIR, Mahan
IPC分类号: C07K16/28
CPC分类号: C07K16/2875 , A61K2039/505 , C07K16/2878 , C07K2317/22 , C07K2317/24 , C07K2317/34 , C07K2317/41 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94
摘要: The present invention relates to antibodies and antigen binding fragments thereof which bind to the human CD70 protein with high affinity and display potent inhibition of tumor cell growth.