公开(公告)号：EP3384047A1

公开(公告)日：2018-10-10

申请号：EP16819968.5

申请日：2016-12-01

申请人： bioMérieux ,  Hospices Civils De Lyon ,  Université Claude Bernard Lyon I

发明人： CERRATO, Elisabeth ,  DELWARDE, Benjamin ,  MONNERET, Guillaume ,  PERONNET, Estelle ,  TEXTORIS, Julien ,  VENET, Fabienne

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158

摘要： The invention relates to an
in vitro or
ex vivo method for assessing the risk of complication in patients who have suffered an attack or infection resulting in systemic inflammatory response syndrome. The invention is characterized in that it comprises the step of detecting, in a biospecimen collected from said patient, at least one transcript of the IL7R gene, as well as the use of assaying,
in vitro or
ex vivo , the amount of at least one transcript of the IL7R gene, in a biospecimen collected from a patient who has suffered an attack or infection resulting in systemic inflammatory response syndrome, to assess the risk of complication, and in particular mortality, in said patient. The invention also relates to kits for assaying,
in vitro or
ex vivo , the amount of at least one transcript of the IL7R gene in a biospecimen.