公开(公告)号：EP1899434A1

公开(公告)日：2008-03-19

申请号：EP06778734.1

申请日：2006-06-30

申请人： bioMérieux S.A. ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  Instituto Superior Técnico

发明人： CHARREYRE, Marie-Thérèse ,  MANDRAND, Bernard ,  MARTINHO, José, Manuel, Gaspar ,  RELOGIO, Paula ,  SEQUEIRA FARINHA, José, Paulo

IPC分类号： C09K11/06 ,  C08F2/38 ,  C08F22/40 ,  C08F8/00 ,  C09B69/10 ,  C07K17/08 ,  C07K17/10 ,  C12N11/06

CPC分类号： C08F8/30 ,  C08F2/38 ,  C08F8/34 ,  C08F220/36 ,  C09B69/103 ,  C09B69/109

摘要： The invention relates to fluorescent polymers soluble in an aqueous solution carrying at least 5 fluorophores which are distributed on a polymer and exhibit the following properties: fluorophores are water-soluble, the fluorophores are not self-associated in water at a concentration equal to or less than 10-4 mol/l, preferably a concentration equal to or less than 10-3 mol/l, the fluorophores which are free in the aqueous solution have a molar extinction coefficient greater than 1000 M-1?cm-1, , the fluorophores which are free in the aqueous solution have a quantum efficiency greater than 0.3, preferably greater than 0.6, said polymers have a fluorescence amplification factor equal to or greater than 0.35 per polymer Kg/mol, preferably greater than 0.45 per polymer Kg/mol.

摘要翻译： 本发明涉及一种荧光聚合物在携带它们分布在聚合物上和至少5的荧光团wässrige溶液易溶于表现出以下性质：荧光团是水溶性的，荧光团不是自相关在水中的更低的浓度 大于或等于10 -4摩尔/升，优选在小于或等于10 -3摩尔/升的浓度，其中在wässrige溶液不含荧光团具有摩尔消光系数大于1000 M-1· -1，优选高于5000 M-1·厘米-1，其中在wässrige溶液不含荧光团具有大于0.3的量子产率，优选地大于0.6时，具有大于或的荧光放大率所述聚合物 等于0:35每kg /聚合物的mol，优选大于0:45每kg /聚合物的摩尔更大。