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    CYTOKINE BINDING DOMAINS
    6.
    发明公开
    CYTOKINE BINDING DOMAINS 审中-公开
    细胞因子域

    公开(公告)号：EP1709074A1

    公开(公告)日：2006-10-11

    申请号：EP04802064.8

    申请日：2004-12-16

    申请人： Commonwealth Scientific and Industrial Research Organization (CSIRO)

    发明人： VARGHESE, Joseph, Noozhumutry ,  HUDSON, Peter, John ,  POWER, Barbara, Elaine

    IPC分类号： C07K14/715 ,  C12N15/12

    CPC分类号： C07K14/715

    摘要： The present invention relates a method of generating modified binding moieties comprising a cytokine binding domain consisting of a first FnIII-like domain and a second FnIII-like domain in which at least one amino acid residue within the cytokine binding domain in modified such that the binding characteristics of the cytokine binding domain are altered, and/or, the solubility and/or stability of the binding moiety is improved. The invention also relates to binding moieties and to the use of such binding moieties as affinity reagents, diagnostic reagents, therapeutic agents and protein scaffolds.

    A DETECTION SYSTEM FOR USE IN AN AIRCRAFT
    8.
    发明公开
    A DETECTION SYSTEM FOR USE IN AN AIRCRAFT 失效
    用于飞机的检测系统

    公开(公告)号：EP0525007A4

    公开(公告)日：1993-06-02

    申请号：EP91907594

    申请日：1991-04-09

    申请人： COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION

    发明人： PRATA, ALFREDO, JOSE ,  BARTON, IAN, JAMES

    IPC分类号： B64D45/00 ,  G01J5/60 ,  G01S3/781 ,  G01S3/787 ,  G01W1/08 ,  H04N5/33 ,  G01J3/28 ,  G01J1/42

    CPC分类号： H04N5/332 ,  G01J5/60 ,  G01S3/781 ,  G01S3/787 ,  G01W2001/003 ,  H04N5/33

    摘要： A detection system for use in an aircraft which is able to monitor atmospheric conditions ahead of the aircraft, generate an alarm signal if adverse atmospheric conditions exist ahead of the aircraft and generate information which indicates the position of the adverse conditions so the adverse conditions can be avoided. The system is able to detect the presence of volcanic ash cloud ahead of the aircraft and, if desired, can also be used to detect a high density of sulphur dioxide gas and/or clear air turbulence ahead of the aircraft. The system monitors infrared radiation received by the aircraft, generates intensity signals representative of at least one predetermined wavelength of the radiation and compares intensity signals with reference signals or intensity signals of another infrared wavelength. If the results of the comparison which indicate the adverse conditions are present, an adverse condition warning signal is generated and the device is also able to generate video display signals for producing a video display which indicates the position of the adverse conditions relative to the aircraft.

    摘要翻译： 一种用于航空器的检测系统，其能够监测飞机前的大气条件，如果飞机之前存在不利的大气条件，则产生报警信号，并产生指示不利条件的位置的信息，以使不利条件可以 避免。 该系统能够检测飞机前面的火山灰云的存在，并且如果需要，还可以用于在飞行器之前检测高密度的二氧化硫气体和/或空气湍流。 该系统监视由飞行器接收的红外辐射，产生表示辐射的至少一个预定波长的强度信号，并将强度信号与另一个红外波长的参考信号或强度信号进行比较。 如果比较结果表示存在不利条件，则产生不利条件警告信号，并且该装置还能够产生用于产生视频显示的视频显示信号，该视频显示指示不利条件相对于飞行器的位置。