公开(公告)号：EP0979661A1

公开(公告)日：2000-02-16

申请号：EP99119531.4

申请日：1995-09-13

申请人： LABORATOIRE GLAXO WELLCOME

发明人： Schaeffer, Alain Emile Edouard, Laboratories Glaxo ,  Seguelas, Etienne, APE Medical

IPC分类号： A61M15/00

CPC分类号： A61M15/0065 ,  A61M15/0068 ,  A61M2202/064 ,  G06F19/00

摘要： An inhalation device is provided by means of which material in powder form can be inhaled. The device comprises a body (55) defining a reservoir (56) for medicaments in powder form, an outlet (57) through which a user can inhale and a dosing member (53) with at least one metering recess (65) formed therein. The dosing member (53) is moveable between a position in which the at least one metering recess (65) communicates with the reservoir (56) to receive a dose of powder therefrom and a position in which the at least one metering recess (65) communicates with the outlet (57) to permit the user to inhale the dose. The at least one metering recess (65) is formed in a face of the dosing member (53), the said face being mounted in contact against a similar mating face (60) of the body (55) at the lower end of the reservoir (56). At least one moveable weight may be incorporated within the device, adapted to strike an anvil surface when the device is shaken.

摘要翻译： 提供吸入装置，通过该装置可以吸入粉末形式的材料。 该装置包括：主体（55），其限定用于粉末形式的药物的储存器（56），用户可以吸入的出口（57）和具有形成在其中的至少一个计量凹部（65）的计量构件（53）。 计量构件（53）可在其中至少一个计量凹部（65）与储存器（56）连通的位置之间移动以从其中接收一定剂量的粉末，并且其中至少一个计量凹部（65） 与出口（57）连通以允许使用者吸入剂量。 所述至少一个计量凹部（65）形成在所述计量构件（53）的表面中，所述面部安装成与所述主体（55）的类似配合面（60）抵接在所述储存器的下端 （56）。 至少一个可移动的重物可以结合在该装置内，适于当装置被摇动时撞击砧座表面。

公开(公告)号：EP0639072B1

公开(公告)日：1998-03-11

申请号：EP93909884.4

申请日：1993-05-03

申请人： LABORATOIRE GLAXO WELLCOME

发明人： MERLET, Nadine Laboratoires Glaxo S.A. ,  RICHARD, Isabelle Laboratoires Glaxo S.A. ,  THIELEMANS, Isabelle Laboratoires Glaxo S.A.

IPC分类号： A61K31/40 ,  A61K31/445

CPC分类号： A61K9/02 ,  A61K31/00 ,  A61K31/40 ,  A61K31/445

公开(公告)号：EP0700290B1

公开(公告)日：1999-08-25

申请号：EP94918355.2

申请日：1994-05-24

申请人： LABORATOIRE GLAXO WELLCOME (S.A.)

发明人： THIELEMANS, Isabelle ,  RICHARD, Isabelle

IPC分类号： A61K31/415 ,  A61K9/02

CPC分类号： A61K9/02 ,  A61K31/415

摘要： The invention relates to a pharmaceutical composition for rectal administration which comprises 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)-methyl]-4H-carbazol-4-one in the form of its free base or a pharmaceutically acceptable solvate thereof as active ingredient, together with one or more pharmaceutically acceptable carriers or excipients. Methods for the manufacture of such compositions and for their use in the treatment of conditions mediated through the action of 5-hydroxytryptamine at 5-HT3 receptors are also described.

公开(公告)号：EP0835146A2

公开(公告)日：1998-04-15

申请号：EP95932737.0

申请日：1995-09-13

申请人： LABORATOIRE GLAXO WELLCOME

发明人： SCHAEFFER, Alain, Emile, Edouard ,  SEGUELAS, Etienne, APE Medical

IPC分类号： A61M ,  A61M15

CPC分类号： A61M15/0065 ,  A61M15/0068 ,  A61M2202/064 ,  G06F19/00

摘要： An inhalation device is provided by means of which material in powder form can be inhaled. The device comprises a body (55) defining a reservoir (56) for medicaments in powder form, an outlet (57) through which a user can inhale and a dosing member (53) with at least one metering recess (65) formed therein. The dosing member (53) is moveable between a position in which the at least one metering recess (65) communicates with the reservoir (56) to receive a dose of powder therefrom and a position in which the at least one metering recess (65) communicates with the outlet (57) to permit the user to inhale the dose. The at least one metering recess (65) is formed in a face of the dosing member (53), the said face being mounted in contact against a similar mating face (60) of the body (55) at the lower end of the reservoir (56). At least one moveable weight may be incorporated within the device, adapted to strike an anvil surface when the device is shaken.

摘要翻译： 提供吸入装置，借助于吸入装置可以吸入粉末形式的材料。 该装置包括限定用于粉末形式的药物的贮存器（56）的主体（55），用户可以吸入的出口（57）和具有至少一个计量凹槽（65）的计量构件（53）。 定量给料件（53）可在至少一个计量凹槽（65）与贮存器（56）连通以从其接收粉末剂量的位置与其中至少一个计量凹槽（65） 与出口（57）连通以允许使用者吸入剂量。 所述至少一个计量凹槽（65）形成在所述定量给料构件（53）的表面中，所述表面安装成在所述贮存器的下端处抵靠所述本体（55）的类似配合面（60） （56）。 至少一个可移动的重物可以被结合在装置内，适于在装置被摇动时撞击砧座表面。