公开(公告)号：EP0837703A1

公开(公告)日：1998-04-29

申请号：EP96923757.0

申请日：1996-07-12

申请人： RIVER MEDICAL, INC.

发明人： SANCOFF, Gregory, E. ,  DOYLE, Mark, C. ,  FIELD, Frederic, P.

IPC分类号： A61M5

CPC分类号： A61M5/14593 ,  A61M2005/14204

摘要： The present invention relates to apparatus (5) and method for the controlled delivery of fluid. The apparatus (5) comprises chemical reactants (65, 70) which combine to generate gas and create pressure to drive a fluid (20) from a container (17). The reactants (65, 70) and the environment in which the reaction occurs are controlled, thereby causing the fluid (20) to be delivered from the device (5) at a predetermined flow rate.

公开(公告)号：EP0781147A1

公开(公告)日：1997-07-02

申请号：EP95933800.0

申请日：1995-09-15

申请人： RIVER MEDICAL, INC.

发明人： SANCOFF, Gregory, E. ,  DOYLE, Mark, C. ,  FIELD, Frederic, P.

IPC分类号： A61M5 ,  A61J1 ,  B01J7 ,  B65D83 ,  B05B11

CPC分类号： A61M5/14593 ,  A61M5/1409 ,  A61M5/1483 ,  A61M2005/1404 ,  A61M2005/14204 ,  B01J7/02 ,  B65D83/625 ,  Y10S128/12

摘要： We disclose apparatus and methods for delivering for patient infusion or other use two or more fluids either sequentially or simultaneously. The apparatus (100) has a fluid delivery compartment (101) containing a first infusion fluid (103), a flexible membrane (104), and an openable bag (150) containing a second infusion fluid (152). An attached gas reaction compartment (121) contains chemical reactants (123, 134) which, when combined, react to evolve gas (122). The gas (122) expands a gas expansion chamber (102) causing the membrane (104) to move into the fluid delivery compartment (101), displacing the first infusion fluid (103). The membrane (104) eventually contacts and compresses the openable bag (150). Pressure from the membrane (104) causes the bag (150) to open and discharge its contents out of the infusion device (100).

摘要翻译： 我们公开了用于递送用于患者输注或其他用途的两种或更多种流体的装置和方法，所述流体或者顺序地或者同时递送。 装置（100）具有包含第一输注流体（103），柔性膜（104）和容纳第二输注流体（152）的可开启袋（150）的流体输送隔室（101）。 附接的气体反应隔室（121）包含化学反应物（123,134），所述化学反应物在组合时反应以产生气体（122）。 气体（122）使气体膨胀室（102）膨胀，使膜（104）移动到流体输送隔室（101）中，从而移位第一输注流体（103）。 膜（104）最终接触并压缩可开袋（150）。 来自膜（104）的压力导致袋（150）打开并将其内容物排出输注装置（100）。

公开(公告)号：EP0711243A4

公开(公告)日：1997-01-08

申请号：EP94925217

申请日：1994-08-08

申请人： RIVER MEDICAL INC

发明人： SANCOFF GREGORY E ,  DOYLE MARK C ,  FIELD FREDERIC P

IPC分类号： F16K17/02 ,  A61M5/142 ,  A61M5/145 ,  B01J7/02 ,  B05B11/00 ,  B65D83/14

CPC分类号： B65D83/625 ,  A61M5/14593 ,  B01J7/02 ,  B05B11/0045

摘要： A liquid dispensing device (2) and a method of dispensing liquid are disclosed. The device (2) includes a hollow gas and liquid tight casing (4), a flexible gas and liquid tight membrane (18, 130) having at least one convolution (132) and disposed across the casing interior and dividing the interior into a propellant chamber (36) and a liquid chamber (24), an outlet port (28) from the liquid chamber (24), two mutually reactive chemicals (38, 40) in the propellant chamber (36) but reactive upon contact to form a propellant gas. Upon generation of the gas, the gas expands against the membrane (18, 130), pressurizing the liquid chamber (24) to expel the contained liquid through the outlet port (28). A pressure relief valve (45), suitable for use with the device, allows gas to escape from the device when the gas pressure exceeds a predetermined level.

摘要翻译： 公开了一种液体分配装置（2）和一种分配液体的方法。 装置（2）包括中空气体和不透液体的壳体（4），具有至少一个回旋部（132）的柔性气体和液体密封膜（18,130），所述柔性气体和液体密封膜横跨壳体内部布置并将内部分成推进剂 （36）和液体腔室（24），液体腔室（24）的出口端口（28），推进剂腔室（36）中的两种相互反应的化学物质（38,40），但在接触时反应以形成推进剂 加油站。 在产生气体时，气体膨胀靠着隔膜（18,130），加压液体腔室（24）以通过出口端口（28）排出所容纳的液体。 当气体压力超过预定水平时，适合与该装置一起使用的泄压阀（45）允许气体从装置中逸出。

公开(公告)号：EP0748252A1

公开(公告)日：1996-12-18

申请号：EP95911857.0

申请日：1995-02-21

申请人： RIVER MEDICAL, INC.

发明人： SANCOFF, Gregory, E. ,  DOYLE, Mark, C. ,  FIELD, Frederic, P.

IPC分类号： A61M5 ,  A61J1 ,  B01J7 ,  B65D83 ,  C01B31 ,  C01D7 ,  B05B11

CPC分类号： A61M5/155 ,  A61M5/1409 ,  A61M5/14593 ,  A61M5/1483 ,  A61M2005/1404 ,  A61M2005/14204 ,  B01J7/02 ,  B65D83/625

摘要： An apparatus for dispensing a fluid, comprising a container for holding the fluid to be dispensed and a housing for holding a solid chemical and a liquid chemical which react to generate carbon dioxide gas upon contact, such that the gas is used to drive the fluid out of the container.

公开(公告)号：EP0837703A4

公开(公告)日：1999-08-25

申请号：EP96923757

申请日：1996-07-12

申请人： RIVER MEDICAL INC

发明人： SANCOFF GREGORY E ,  DOYLE MARK C ,  FIELD FREDERIC P

IPC分类号： A61M5/142 ,  A61M5/145 ,  A61M1/00 ,  B65D83/14

CPC分类号： A61M5/14593 ,  A61M2005/14204

摘要： The present invention relates to apparatus (5) and method for the controlled delivery of fluid. The apparatus (5) comprises chemical reactants (65, 70) which combine to generate gas and create pressure to drive a fluid (20) from a container (17). The reactants (65, 70) and the environment in which the reaction occurs are controlled, thereby causing the fluid (20) to be delivered from the device (5) at a predetermined flow rate.

公开(公告)号：EP0713409A4

公开(公告)日：1997-02-26

申请号：EP94924594

申请日：1994-08-08

申请人： RIVER MEDICAL INC

发明人： SANCOFF GREGORY E ,  DOYLE MARK C ,  FIELD FREDERIC P

IPC分类号： A61M39/02 ,  A61J1/00 ,  A61J1/14 ,  A61J1/20 ,  A61M37/00 ,  B01J7/02

CPC分类号： A61J1/2089 ,  A61J1/1425 ,  A61J1/1468 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2055 ,  B01J7/02

摘要： A device is disclosed which provides direct and effective incorporation of material, such as medicine, from a vial into the interior of a dispensing device. The device has a vial adaptor (150) for engaging the vial, a connector (160) for joining the vial adaptor and the container of fluid, a conduit (155), such as a needle, which provides fluid communication between the vial and the container, and a reclosable valve (164). The device can also provide for attaching the vial to a dispensing device but without intially establishing liquid communication between the two.

公开(公告)号：EP0781147A4

公开(公告)日：1998-11-25

申请号：EP95933800

申请日：1995-09-15

申请人： RIVER MEDICAL INC

发明人： SANCOFF GREGORY E ,  DOYLE MARK C ,  FIELD FREDERIC P

IPC分类号： A61M5/00 ,  A61J1/00 ,  A61J1/14 ,  A61J1/20 ,  A61M5/14 ,  A61M5/142 ,  A61M5/145 ,  A61M5/148 ,  B01J7/02 ,  B05B11/00 ,  B65D83/14

CPC分类号： A61M5/14593 ,  A61M5/1409 ,  A61M5/1483 ,  A61M2005/1404 ,  A61M2005/14204 ,  B01J7/02 ,  B65D83/625 ,  Y10S128/12

摘要： We disclose apparatus and methods for delivering for patient infusion or other use two or more fluids either sequentially or simultaneously. The apparatus (100) has a fluid delivery compartment (101) containing a first infusion fluid (103), a flexible membrane (104), and an openable bag (150) containing a second infusion fluid (152). An attached gas reaction compartment (121) contains chemical reactants (123, 134) which, when combined, react to evolve gas (122). The gas (122) expands a gas expansion chamber (102) causing the membrane (104) to move into the fluid delivery compartment (101), displacing the first infusion fluid (103). The membrane (104) eventually contacts and compresses the openable bag (150). Pressure from the membrane (104) causes the bag (150) to open and discharge its contents out of the infusion device (100).

摘要翻译： 我们公开了用于递送用于患者输注或其他用途的两种或更多种流体的装置和方法，所述流体或者顺序地或者同时递送。 装置（100）具有包含第一输注流体（103），柔性膜（104）和容纳第二输注流体（152）的可开启袋（150）的流体输送隔室（101）。 附接的气体反应隔室（121）包含化学反应物（123,134），所述化学反应物在组合时反应以产生气体（122）。 气体（122）使气体膨胀室（102）膨胀，使膜（104）移动到流体输送隔室（101）中，从而移位第一输注流体（103）。 膜（104）最终接触并压缩可开袋（150）。 来自膜（104）的压力导致袋（150）打开并将其内容物排出输注装置（100）。

公开(公告)号：EP0713409A1

公开(公告)日：1996-05-29

申请号：EP94924594.0

申请日：1994-08-08

申请人： RIVER MEDICAL, INC.

发明人： SANCOFF, Gregory, E. ,  DOYLE, Mark, C. ,  FIELD, Frederic, P.

IPC分类号： A61M39 ,  A61J1 ,  A61M37 ,  B01J7

CPC分类号： A61J1/2089 ,  A61J1/1425 ,  A61J1/1468 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2055 ,  B01J7/02

摘要： A device is disclosed which provides direct and effective incorporation of material, such as medicine, from a vial into the interior of a dispensing device. The device has a vial adaptor (150) for engaging the vial, a connector (160) for joining the vial adaptor and the container of fluid, a conduit (155), such as a needle, which provides fluid communication between the vial and the container, and a reclosable valve (164). The device can also provide for attaching the vial to a dispensing device but without intially establishing liquid communication between the two.

公开(公告)号：EP0711243A1

公开(公告)日：1996-05-15

申请号：EP94925217.0

申请日：1994-08-08

申请人： RIVER MEDICAL, INC.

发明人： SANCOFF, Gregory, E. ,  DOYLE, Mark, C. ,  FIELD, Frederic, P.

IPC分类号： F16K17 ,  A61M5 ,  B01J7 ,  B65D83 ,  B05B11

CPC分类号： B65D83/625 ,  A61M5/14593 ,  B01J7/02 ,  B05B11/0045

摘要： A liquid dispensing device (2) and a method of dispensing liquid are disclosed. The device (2) includes a hollow gas and liquid tight casing (4), a flexible gas and liquid tight membrane (18, 130) having at least one convolution (132) and disposed across the casing interior and dividing the interior into a propellant chamber (36) and a liquid chamber (24), an outlet port (28) from the liquid chamber (24), two mutually reactive chemicals (38, 40) in the propellant chamber (36) but reactive upon contact to form a propellant gas. Upon generation of the gas, the gas expands against the membrane (18, 130), pressurizing the liquid chamber (24) to expel the contained liquid through the outlet port (28). A pressure relief valve (45), suitable for use with the device, allows gas to escape from the device when the gas pressure exceeds a predetermined level.