摘要:
Hair styling accessories are disclosed herein for holding, securing and styling hair. The accessories provide a mechanism for holding a ponytail in a wearer's hair, and/or for allowing hair to be secured, pulled, rolled and styled in a desirable manner. In some embodiments, faceted gem features are displayed. In some further embodiments, synthetic hair-like material is secured to the accessories.
摘要:
There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein Y, Z and R 1 to R 6 have meanings given in the description, for use in the treatment of melanoma or renal cancer by administration of said compound, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog. There is also provided the use of a compound of formula (I) for the production of a medicament for administration, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog, for treating melanoma or renal cancer.
摘要:
There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein Y, Z and R 1 to R 6 have meanings given in the description, for use in the treatment of melanoma or renal cancer by administration of said compound, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog. There is also provided the use of a compound of formula (I) for the production of a medicament for administration, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog, for treating melanoma or renal cancer.
摘要:
The hair clip comprises two combs (12) and at least one elastic member (14) to bias the teeth (12.2) of the combs towards each other in overlapping relationship. The teeth of the combs are similar and are at least slightly wider than the spaces (18) between the teeth. In use, the combs may be twisted relatively to each other while inserting them into engagement, such that some of the teeth of one comb overlay and others underlay the teeth of the other comb so as to clamp hair between the two combs. Preferably the teeth are oval or elliptical in cross-section, such that they interfit partially with the teeth with which they are engaged.
or a pharmaceutically acceptable salt thereof, wherein Y, Z and R 1 to R 6 have meanings given in the description, for use in the treatment of melanoma or renal cancer by administration of said compound, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog. There is also provided the use of a compound of formula (I) for the production of a medicament for administration, in the same or separate pharmaceutical composition, with paclitaxel or a paclitaxel analog, for treating melanoma or renal cancer.
摘要:
An interferometery system (110) for making interferometric measurements of an object, the system including: a beam generation module (124) which during operation delivers an output beam that includes a first beam at a first frequency and a second beam at a second frequency that is different from the first frequency, the first and second beams within the output beam being coextensive, the beam generation module including a beam conditioner (122) which during operation introduces a sequence of different shifts in a selected parameter of each of the first and second beams, the selected parameter selected from a group consisting of phase and frequency; a detector assembly having a detector element (170); and an interferometer constructed to receive the output beam at least a part of which represents a first measurement beam at the first frequency and a second measurement beam at the second frequency, the interferometer further constructed to image both the first and second measurement beams onto a selected spot on the object (160) to produce therefrom corresponding first and second return measurement beams, and to then simultaneously image the first and second return measurement beams onto said detector element (170).
摘要:
One embodiment of the present invention is a compound represented by Structural Formula (I) wherein Y is a covalent bond of a substituted or unsubstituted straight chained hydrocarbyl group. In addition, Y, taken together with both >C=Z groups to which it is bonded, is a substituted or unsubstituted aromatic group. Preferably, Y is a covalent bond or -C(R7R8)-. R1 is an aliphatic group, a substituted aliphatic group, a non-aromatic hetereocyclic group, or a substituted non-aromatic hetereocyclic group, R2-R4 are independently -H, an aliphatic group, a substituted aliphatic group, a non-aromatic hetereocyclic group, a substituted non-aromatic hetereocyclic group, an aryl group or a substituted aryl group, or R1 and R3 taken together with the carbon and nitrogen atoms to which they are bonded, and/or R2 and R4 taken together with the carbon and nitrogen atoms to which they are bonded, form a non-aromatic heterocyclic ring optionally fused to an aromatic ring. R5-R6 are independently -H, an aliphatic group, a substituted aliphatic group, an aryl group or a substituted aryl group. R7 and R8 are each independently -H, an aliphatic or substituted aliphatic group, or R7 is -H and R8 is a substituted or unsubstituted aryl group, or, R7 and R8, taken together, are a C2-C6 substituted or unsubstituted alkylene group. Z is =0 or =S. Also disclosed are pharmaceutical compositions comprising the compound of the present invention and a pharmaceutically acceptable carrier or diluent.
摘要翻译:本发明的一个实施方案是由结构式(I)表示的化合物,其中Y是取代或未取代的直链烃基的共价键。 另外,Y与它所键合的> C = Z基团一起是取代或未取代的芳族基团。 优选地,Y是共价键或-C(R 7 R 8) - 。 R 1为脂族基团,取代的脂族基团,非芳族杂环基团或取代的非芳族杂环基团,R 2 -R 4独立地为-H,脂族基团,取代的脂族基团,非芳族杂环基团 ,取代的非芳族杂环基团,芳基或取代的芳基,或者R 1和R 3与它们所键合的碳原子和氮原子一起,和/或R 2和R 4与碳原子和氮原子一起 它们键合到一起形成任选与芳环稠合的非芳族杂环。 R5-R6独立地为-H,脂族基团,取代的脂族基团,芳基或取代的芳基。 R7和R8各自独立地为-H,脂族或取代的脂族基团,或R7为-H和R8为取代或未取代的芳基,或者R7和R8一起为C2-C6取代或未取代的亚烷基 。 Z是= 0或= S。 还公开了包含本发明化合物和药学上可接受的载体或稀释剂的药物组合物。