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    OCULAR RADIOSURGERY
    2.
    发明公开
    OCULAR RADIOSURGERY 审中-公开

    公开(公告)号：EP2992863A1

    公开(公告)日：2016-03-09

    申请号：EP15186581.3

    申请日：2007-10-16

    申请人： Oraya Therapeutics, INC.

    发明人： GERTNER, Michael ,  CHELL, Erik ,  HANSEN, Steven ,  ARNOLDUSSEN, Mark ,  HERRON, Matt ,  PAN, Kuang-Hung

    IPC分类号： A61F9/008 ,  A61B3/00

    CPC分类号： A61N5/1049 ,  A61B6/506 ,  A61B2017/306 ,  A61F9/009 ,  A61N5/1017 ,  A61N5/103 ,  A61N2005/105 ,  A61N2005/1056 ,  A61N2005/1091

    摘要： A radiosurgery system describes a therapeutic radiation delivery to a target structure in a patient. The radiosurgery system treats inflammatory ocular disorders; places ocular structures in a global coordinate system based on ocular imaging; automates ocular structures inside the global coordinate system to direction of a positioning system that is directed based on ocular structures within the coordinate system; tracks and relates the position of ocular structures to the status of the radiosurgery system; determines beam energy and direction and duration of time for treatment for a specific disease to be treated and/or structures to be avoided; tracks structure of an eye; holds and fixes the eye is in place; places a fiducial is on the eye to aid in positioning; positions the eye off the refelction; and combines with other treatments and can be delivered concomitant with, prior to, or following other treatments.

    METHODS AND DEVICES FOR DETECTING, CONTROLLING, AND PREDICTING RADIATION DELIVERY
    5.
    发明公开
    METHODS AND DEVICES FOR DETECTING, CONTROLLING, AND PREDICTING RADIATION DELIVERY 有权
    器件的检测，控制和预测辐射分布

    公开(公告)号：EP2231277A2

    公开(公告)日：2010-09-29

    申请号：EP08867850.3

    申请日：2008-12-18

    申请人： Oraya Therapeutics, INC.

    发明人： GERTNER, Michael ,  ARNOLDUSSEN, Mark ,  CHELL, Erik ,  HANSEN, Steven, D. ,  HERRON, Matt ,  KORUGA, Igor ,  LIANG, Junzhong

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1067 ,  A61F9/008 ,  A61F2009/00844 ,  A61F2009/00863 ,  A61N5/1017 ,  A61N5/1049 ,  A61N2005/1059 ,  A61N2005/1072 ,  A61N2005/1091

    摘要： Embodiments provide method/systems for determining alignment of a patient's body part, such as an eye, in an external coordinate system of a treatment or diagnostic device, such as a radiotherapy device, so as to define a reference axis for guiding device operation. Additional embodiments provide image-based methods/systems for aligning, tracking and monitoring motion of a body part and a treatment target in relation to a radiation beam axis. Particular ophthalmic embodiments provide method/systems including an eye- contact guide device and imaging system for aligning and tracking motion of an eye and ocular treatment target in relation to an orthovoltage X-ray beam axis, so as to monitor application of radiation to a lesion, such as a macular lesion of the retina. Particular methods for controlling radiation in response to motion of the target during treatment are described to ensure treatment goals and avoid exposure to sensitive structures.

    摘要翻译： 实施例的用于在患者身体部分的确定性采矿对准，颜色提供的方法和系统：诸如眼睛，在到外部坐标治疗或诊断装置，检测作为放射治疗装置的系统中，以便限定一个参考轴线，用于引导设备的操作。 其它实施方案提供用于对准，跟踪和监测的身体部分的运动和治疗目标相对于辐射束轴线的基于图像的方法和系统。 特定眼科实施例提供了方法和系统，其包括用于相对于对准和跟踪眼睛和眼睛治疗目标的运动，以邻电压X射线束轴的眼接触的导向装置和成像系统，以便监控应用辐射到病变 ，求作为视网膜黄斑病变。 描述了用于在治疗期间，响应于所述目标的运动控制辐射特定的方法，作为搜索算法用于选通或中断辐射发射，既保证治疗目标并避免暴露在敏感结构。

    METHODS AND DEVICES FOR ORTHOVOLTAGE OCULAR RADIOTHERAPY AND TREATMENT PLANNING
    6.
    发明公开
    METHODS AND DEVICES FOR ORTHOVOLTAGE OCULAR RADIOTHERAPY AND TREATMENT PLANNING 审中-公开
    方法和设备目镜ORTHO电压放射治疗和治疗计划

    公开(公告)号：EP2231276A1

    公开(公告)日：2010-09-29

    申请号：EP08859241.5

    申请日：2008-10-31

    申请人： Oraya Therapeutics, INC.

    发明人： GERTNER, Michael ,  ARNOLDUSSEN, Mark ,  CHELL, Erik ,  HANSEN, Steven, D. ,  LIANG, Junzhong

    IPC分类号： A61N5/10

    CPC分类号： A61N5/1037 ,  A61N5/1017 ,  A61N5/103 ,  A61N5/1064 ,  A61N2005/1091

    摘要： A method, code and system for planning the treatment a lesion on or adjacent to the retina of an eye of a patient are disclosed. There is first established at least two beam paths along which x-radiation is to be directed at the retinal lesion. Based on the known spectral and intensity characteristics of the beam, a total treatment time for irradiation along each beam paths is determined. From the coordinates of the optic nerve in the aligned eye position, there is determined the extent and duration of eye movement away from the aligned patient-eye position in a direction that moves the patient's optic nerve toward the irradiation beam that will be allowed during treatment, while still maintaining the radiation dose at the patient optic nerve below a predetermined dose level.

    Particle beam irradiation facility for treating ocular tumors
    8.
    发明公开
    Particle beam irradiation facility for treating ocular tumors 有权
    Teilchenstrahlbestrahlungssystem照射眼肿瘤

    公开(公告)号：EP1935453A3

    公开(公告)日：2009-02-18

    申请号：EP07115082.5

    申请日：2007-08-28

    申请人： SIEMENS AKTIENGESELLSCHAFT

    发明人： Grözinger, Sven Oliver, Dr. ,  Moyers, Michael Farley, Dr.

    IPC分类号： A61N5/10 ,  A61F9/00

    CPC分类号： A61N5/1049 ,  A61F9/00 ,  A61N5/1017 ,  A61N2005/1087

    摘要： A system for treating an ocular tumor having a cone, a collimator, a light source and a camera is disclosed. The cone includes a cone input and a cone output and is capable of being mounted and un-mounted to a treatment nozzle. The cone input receives radiation from the treatment nozzle for the treatment of the ocular tumor. The collimator is coupled to the cone output and configured to collimate radiation received by the cone output. This collimated radiation is directed to the patient having the ocular tumor. The light source coupled to the cone. The light source is configured to provide a focusing point of the eye of the patient. A camera coupled to the cone monitors the position of the eye of the patient.

    ENDOCURIETHERAPY
    9.
    发明公开
    ENDOCURIETHERAPY 失效

    公开(公告)号：EP0500928A1

    公开(公告)日：1992-09-02

    申请号：EP91919975.0

    申请日：1991-08-09

    申请人： GOOD, Roger R.

    发明人： GOOD, Roger R.

    IPC分类号： A61K51 ,  A61N1 ,  A61N2 ,  A61N5 ,  A61P35 ,  C23C14 ,  C23C26 ,  C23C28 ,  G21G4

    CPC分类号： C23C14/223 ,  A61K51/1241 ,  A61N5/1017 ,  A61N5/1027 ,  A61N2005/1019 ,  A61N2005/1023 ,  C23C14/0057 ,  C23C14/30 ,  C23C14/3407 ,  C23C14/50 ,  C23C14/564 ,  C23C26/00 ,  G21G4/06 ,  G21G4/08 ,  H01J37/34 ,  Y10T29/49

    摘要： Afin de réaliser des implants radioactifs versatiles (10) et de permettre la mise en oeuvre de procédés de radiothérapie variés, on utilise des techniques de placage telles que la pulvérisation pour recouvrir des éléments unitaires, tels que des microsphères, des fils et des rubans, de métaux radioactifs (16), de couches de protection (20) et de couches d'indentification (18). Les éléments solides, radioactifs, multicouches et sans soudures sont implantés individuellement ou combinés dans des applicateurs intercavités, avec des tissus et dans des rubans. Dès lors qu'ils présentent des demi-vies et des intensités sélectionnées, ces éléments permettent d'effectuer un traitement flexible, aussi bien de faible intensité que d'intensité élevée, à l'aide d'implants temporaires ou permanents et d'implants de faible intensité, d'intensité élevée ou d'intensité contrôlée, permettant différents types de thérapies.

    摘要翻译： 为了实现多功能放射性植入物（10）并且允许实施各种放射疗法过程，使用诸如喷涂以覆盖整体元件（诸如微球体，线和带）的电镀技术。 放射性金属（16），保护层（20）和识别层（18）。 固体，放射性，多层和无缝元素单独植入或组合在腔内涂药器中，织物和丝带中。 只要他们选择了半衰期和强度，这些元素允许使用临时或永久植入物和植入物进行灵活的治疗，包括低强度和高强度 低强度，高强度或受控的强度，允许不同类型的治疗。

    OCULAR RADIOSURGERY
    10.
    发明授权
    OCULAR RADIOSURGERY 有权

    公开(公告)号：EP2992863B1

    公开(公告)日：2018-12-12

    申请号：EP15186581.3

    申请日：2007-10-16

    申请人： Carl Zeiss Meditec, Inc.

    发明人： GERTNER, Michael ,  CHELL, Erik ,  HANSEN, Steven ,  ARNOLDUSSEN, Mark ,  HERRON, Matt ,  PAN, Kuang-Hung

    IPC分类号： A61F9/008 ,  A61B3/00

    CPC分类号： A61N5/1049 ,  A61B6/506 ,  A61B2017/306 ,  A61F9/009 ,  A61N5/1017 ,  A61N5/103 ,  A61N2005/105 ,  A61N2005/1056 ,  A61N2005/1091

    摘要： A radiosurgery system describes a therapeutic radiation delivery to a target structure in a patient. The radiosurgery system treats inflammatory ocular disorders; places ocular structures in a global coordinate system based on ocular imaging; automates ocular structures inside the global coordinate system to direction of a positioning system that is directed based on ocular structures within the coordinate system; tracks and relates the position of ocular structures to the status of the radiosurgery system; determines beam energy and direction and duration of time for treatment for a specific disease to be treated and/or structures to be avoided; tracks structure of an eye; holds and fixes the eye is in place; places a fiducial is on the eye to aid in positioning; positions the eye off the refelction; and combines with other treatments and can be delivered concomitant with, prior to, or following other treatments.