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公开(公告)号：EP1907844B1
公开(公告)日：2013-04-03
申请号：EP06747312.4
申请日：2006-06-09
CPC分类号： B01J19/0046 , B01J2219/00162 , B01J2219/00272 , B01J2219/0059 , B01J2219/00594 , B01J2219/00596 , B01J2219/00608 , B01J2219/00617 , B01J2219/00626 , B01J2219/00632 , B01J2219/00659 , B01J2219/00722 , G01N33/54393
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2.发明公开MATERIAU POUR SYNTHESE SUPPORTEE ET PROCEDE DE CROISSANCE D'OLIGONUCLEOTIDES OU DE PEPTIDES 审中-公开材料进行繁殖寡核苷酸或肽支持的综合和方法
公开(公告)号：EP2731734A2
公开(公告)日：2014-05-21
申请号：EP12745892.5
申请日：2012-07-10
CPC分类号： C07K1/042 , B01J2219/00632 , B01J2219/00641 , B01J2219/00722 , B05D1/185 , B05D7/00 , B05D7/22 , B82Y30/00 , C07H21/00 , Y10T428/2982
摘要： The invention relates to a material formed by a porous support onto which functionalised nanoparticles are covalently grafted. The material is characterised in that: at least part of the covalently grafted nanoparticles are housed inside surface pores of the support; and the support is based on silica and takes the form of porous particles of heterogeneous shape and size, the particle size being greater than 1 μm and, preferably, between 5 and 200 μm. The invention also relates to a method for growing oligonucleotides or peptides, characterised in that: the oligonucleotides or peptides are grown on a material formed by a porous support onto which functionalised nanoparticles are covalently grafted, and at least part of the covalently grafted nanoparticles are housed inside surface pores of the support.
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3.发明公开METHOD OF MANUFACTURING PROBE-IMMOBILIZED CARRIER 有权VERFAHREN ZUR HERSTELLUNG EINES SONDENIMMOBILISIERTENTRÄGERS
公开(公告)号：EP1907844A4
公开(公告)日：2009-01-21
申请号：EP06747312
申请日：2006-06-09
申请人： CANON KK
发明人： KAWAMURA MASASHI , OKABE TETSUO
CPC分类号： B01J19/0046 , B01J2219/00162 , B01J2219/00272 , B01J2219/0059 , B01J2219/00594 , B01J2219/00596 , B01J2219/00608 , B01J2219/00617 , B01J2219/00626 , B01J2219/00632 , B01J2219/00659 , B01J2219/00722 , G01N33/54393
摘要： A probe-immobilized carrier for detecting a target substance is manufactured such that a spot is prevented from being contaminated with another spot and a probe is prevented from nonspecifically adsorbing a background area in the manufacture of the probe-immobilized carrier and nonspecific adsorption cannot be occurred even after the formation of an array. A substrate containing a reactive group for immobilizing a probe thereon is used and the steps of: (i) supplying a liquid droplet containing a probe on the substrate; (ii) inactivating a reactive group existing in an area other than a supplying area of the substrate, and (iii) removing an unreacted probe existing in the supplied liquid droplet are carried out.
摘要翻译： 用于检测目标物质的探针固定载体被制造成使得在制造探针固定载体时防止斑点被另一斑点污染并防止探针非特异性地吸附背景区域并且不能发生非特异性吸附 即使在阵列形成之后。 使用含有用于在其上固定探针的反应性基团的基材，并且包括以下步骤：（i）将含有探针的液滴供应到基材上; （ii）使存在于基板的供给区域以外的区域中的反应性基团失活，并且（iii）除去供给的液滴中存在的未反应的探针。
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公开(公告)号：EP1907844A1
公开(公告)日：2008-04-09
申请号：EP06747312.4
申请日：2006-06-09
CPC分类号： B01J19/0046 , B01J2219/00162 , B01J2219/00272 , B01J2219/0059 , B01J2219/00594 , B01J2219/00596 , B01J2219/00608 , B01J2219/00617 , B01J2219/00626 , B01J2219/00632 , B01J2219/00659 , B01J2219/00722 , G01N33/54393
摘要： A probe-immobilized carrier for detecting a target substance is manufactured such that a spot is prevented from being contaminated with another spot and a probe is prevented from nonspecifically adsorbing a background area in the manufacture of the probe-immobilized carrier and nonspecific adsorption cannot be occurred even after the formation of an array. A substrate containing a reactive group for immobilizing a probe thereon is used and the steps of: (i) supplying a liquid droplet containing a probe on the substrate; (ii) inactivating a reactive group existing in an area other than a supplying area of the substrate, and (iii) removing an unreacted probe existing in the supplied liquid droplet are carried out.
摘要翻译： 用于检测目标物质的探针固定载体被制造成使得在制造探针固定载体时防止斑点被另一斑点污染并防止探针非特异性地吸附背景区域并且不能发生非特异性吸附 即使在阵列形成之后。 使用含有用于在其上固定探针的反应性基团的基材，并且包括以下步骤：（i）将含有探针的液滴供应到基材上; （ii）使存在于基板的供给区域以外的区域中的反应性基团失活，并且（iii）除去供给的液滴中存在的未反应的探针。
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