公开(公告)号：EP1379139A2

公开(公告)日：2004-01-14

申请号：EP01271434.1

申请日：2001-12-17

申请人： Insight Strategy & Marketing Ltd.

发明人： YACOBY-ZEEVI, Oron

IPC分类号： A01N63/00

CPC分类号： C12Y302/0105 ,  A61K38/00 ,  A61K2035/122 ,  A61K2035/124 ,  C12N9/2402 ,  C12Y302/01035 ,  C12Y302/01128 ,  C12Y302/01166

摘要： Cell preparations which comprise cells carrying an extracellular matrix degrading enzyme and methods of using such cell preparations for improving transplantation efficiency of such cells.

摘要翻译： 包含携带细胞外基质降解酶的细胞的细胞制剂以及使用这种细胞制剂提高这些细胞的移植效率的方法。

公开(公告)号：EP1159409A4

公开(公告)日：2003-05-02

申请号：EP00908565

申请日：2000-02-10

申请人： INSIGHT STRATEGY & MARKETING

发明人： YACOBY-ZEEVI ORON

IPC分类号： A01K67/027 ,  A61K9/00 ,  A61K35/12 ,  A61K38/00 ,  A61K38/46 ,  A61K38/48 ,  A61K38/51 ,  A61K48/00 ,  A61M15/00 ,  C12N9/24 ,  G06F17/30 ,  G06K9/62 ,  C12N9/26 ,  A61K31/00 ,  A61K38/43 ,  A61K38/47 ,  C12N9/42

CPC分类号： A01K67/0271 ,  A61K9/0073 ,  A61K35/12 ,  A61K38/465 ,  A61K38/486 ,  A61K38/4886 ,  A61K38/51 ,  A61K48/00 ,  A61M15/009 ,  C12N9/2402 ,  C12Y302/01128 ,  C12Y302/01166 ,  G06K9/6282 ,  A61K2300/00 ,  A61K38/00

摘要： A method of inducing bone formation in a subject in need thereof, the method comprises administering to the subject a therapeutically effective amount of heparanase. A pharmaceutical composition for inducing bone formation in a subject in need thereof, the pharmaceutical composition comprises, as an active ingredient, a therapeutically effective amount of heparanase, and a pharmaceutically acceptable carrier.

公开(公告)号：EP1379139A4

公开(公告)日：2004-12-01

申请号：EP01271434

申请日：2001-12-17

申请人： INSIGHT STRATEGY & MARKETING

发明人： YACOBY-ZEEVI ORON

IPC分类号： C12N5/06 ,  A61K35/12 ,  A61K35/14 ,  A61K35/28 ,  A61K38/11 ,  A61K48/00 ,  A61P19/00 ,  C12N5/08 ,  C12N9/24 ,  A61K38/46 ,  A01N63/00

CPC分类号： C12Y302/0105 ,  A61K38/00 ,  A61K2035/122 ,  A61K2035/124 ,  C12N9/2402 ,  C12Y302/01035 ,  C12Y302/01128 ,  C12Y302/01166

摘要： Cell preparations which comprise cells carrying an extracellular matrix degrading enzyme and methods of using such cell preparations for improving transplantation efficiency of such cells.

公开(公告)号：EP1159409A1

公开(公告)日：2001-12-05

申请号：EP00908565.5

申请日：2000-02-10

申请人： Insight Strategy & Marketing Ltd.

发明人： YACOBY-ZEEVI, Oron

IPC分类号： C12N9/26 ,  C12N9/24 ,  C12N9/42 ,  A61K38/00 ,  A61K38/43 ,  A61K38/47 ,  A61K31/00

CPC分类号： A01K67/0271 ,  A61K9/0073 ,  A61K35/12 ,  A61K38/465 ,  A61K38/486 ,  A61K38/4886 ,  A61K38/51 ,  A61K48/00 ,  A61M15/009 ,  C12N9/2402 ,  C12Y302/01128 ,  C12Y302/01166 ,  G06K9/6282 ,  A61K2300/00 ,  A61K38/00

摘要： A method of inducing bone formation in a subject in need thereof, the method comprises administering to the subject a therapeutically effective amount of heparanase. A pharmaceutical composition for inducing bone formation in a subject in need thereof, the pharmaceutical composition comprises, as an active ingredient, a therapeutically effective amount of heparanase, and a pharmaceutically acceptable carrier.