公开(公告)号：EP4356129A1

公开(公告)日：2024-04-24

申请号：EP22738218.1

申请日：2022-06-14

申请人： Abbott Laboratories

发明人： MARINO, Jaime ,  MCQUISTON, Beth ,  DATWYLER, Saul

IPC分类号： G01N33/53 ,  G01N33/68

CPC分类号： G01N33/53 ,  G01N33/6896 ,  G01N2333/91820130101 ,  G01N2800/287120130101

公开(公告)号：EP4436467A1

公开(公告)日：2024-10-02

申请号：EP22896821.0

申请日：2022-11-22

申请人： Brainbox Solutions, Inc.

发明人： EDMONDS, Donna, J. ,  VAN METER, Timothy, E. ,  MIRSHAHI, Nazanin

IPC分类号： A61B5/00 ,  G01N33/50 ,  G01N33/53 ,  C07K14/47

CPC分类号： C07K14/745 ,  A61B5/055 ,  A61B5/0042 ,  A61B5/4064 ,  G01N33/6896 ,  G01N2800/5220130101 ,  G01N2800/287120130101

公开(公告)号：EP4409294A1

公开(公告)日：2024-08-07

申请号：EP22794019.4

申请日：2022-09-28

申请人： Abbott Laboratories

发明人： MCQUISTON, Beth ,  DATWYLER, Saul ,  CHANDRAN, Raj

IPC分类号： G01N33/68

CPC分类号： G01N33/6893 ,  G01N33/6896 ,  G01N2800/2820130101 ,  G01N2800/287120130101

公开(公告)号：EP4429701A1

公开(公告)日：2024-09-18

申请号：EP22893778.5

申请日：2022-11-07

申请人： TrueBinding, Inc.

发明人： SUN, Dongxu ,  RASOOL, Suhail ,  LEONG, Yew Ann ,  HAIG, George M. ,  JOHANSSON, Jenny Ulrika ,  VOLOBOUEVA, Ludmila Anatolievna

IPC分类号： A61K45/06 ,  A61P9/12 ,  A61P37/02 ,  G16H50/30

CPC分类号： G16H50/30 ,  A61P9/12 ,  A61K45/06 ,  G16H20/17 ,  G16H10/40 ,  G01N2800/287120130101 ,  G01N2333/472420130101 ,  G01N2333/7520130101 ,  G01N33/6893 ,  A61K2039/50520130101 ,  A61K2039/54520130101 ,  C07K16/2851 ,  C07K2317/3320130101 ,  C07K2317/7620130101 ,  C07K2317/9220130101 ,  C07K2317/3420130101 ,  C07K2317/2420130101

公开(公告)号：EP4409299A1

公开(公告)日：2024-08-07

申请号：EP22877602.7

申请日：2022-09-30

申请人： Integrated Neurologics LLC

发明人： FLOWER, Todd ,  MATZILEVICH, David

IPC分类号： G01N33/68 ,  G01N33/53

CPC分类号： G01N33/6896 ,  G01N2333/470920130101 ,  G01N2800/287120130101 ,  C07K16/18 ,  G01N2800/5220130101 ,  G01N33/54388 ,  C07K2317/3420130101

公开(公告)号：EP4396587A1

公开(公告)日：2024-07-10

申请号：EP22777531.9

申请日：2022-08-30

申请人： Abbott Laboratories

发明人： ZHANG, Hongwei ,  MCQUISTON, Beth ,  DATWYLER, Saul ,  CHANDRAN, Raj

IPC分类号： G01N33/68

CPC分类号： G01N33/6896 ,  G01N33/6893 ,  G01N2800/287120130101 ,  G01N2800/2820130101

公开(公告)号：EP4390399A1

公开(公告)日：2024-06-26

申请号：EP22216509.4

申请日：2022-12-23

申请人： Uniwersytet Gdanski

发明人： Kote, Sachin ,  Marek-Trzonkowska, Natalia ,  Czaplewska, Paulina ,  Müller, Marc ,  Pirog, Artur ,  Faktor, Jakub

IPC分类号： G01N33/68

CPC分类号： G01N33/6848 ,  G01N33/6842 ,  G01N2570/0020130101 ,  G01N2800/287120130101 ,  G01N33/6893

摘要： The invention relates to 5 serum peptide patterns for diagnostics of acute ischemic stroke (AIS) in humans and differential diagnosis from the intracranial hemorrhagic stroke that are defined using a list of the 100 quantitative peptides that in sera of patients with AIS are increased 2 folds or more as compared with individuals without stroke and patients with intracranial hemorrhagic stroke and a list of 54 qualitative peptides detectable in sera of the patients with AIS but not detectable in the sera of individuals without stroke and in sera of patients with intracranial hemorrhagic stroke.

公开(公告)号：EP3916387B1

公开(公告)日：2024-05-08

申请号：EP20919367.1

申请日：2020-09-07

IPC分类号： G01N33/543

CPC分类号： G01N33/54388 ,  G01N33/6896 ,  G01N2800/287120130101

公开(公告)号：EP4390398A1

公开(公告)日：2024-06-26

申请号：EP22216488.1

申请日：2022-12-23

申请人： Uniwersytet Gdanski

发明人： Kote, Sachin ,  Marek-Trzonkowska, Natalia ,  Czaplewska, Paulina ,  Müller, Marc ,  Pirog, Artur ,  Faktor, Jakub

IPC分类号： G01N33/68 ,  C07K14/00

CPC分类号： G01N33/6893 ,  G01N2800/287120130101 ,  G01N2570/0020130101 ,  C07K14/47

摘要： The invention relates to 4 serum peptide patterns for diagnostics of intracranial hemorrhagic stroke (ICH) in humans and differential diagnosis from acute ischemic stroke that are defined using a list of the 34 quantitative peptides that in sera of patients with ICH are increased 2 folds or more as compared with individuals without stroke and patients with acute ischemic stroke and a list of 16 qualitative peptides detectable in sera of the patients with ICH but not detectable in the sera of individuals without stroke and in sera of patients with acute ischemic stroke.

公开(公告)号：EP4390395A1

公开(公告)日：2024-06-26

申请号：EP22216500.3

申请日：2022-12-23

申请人： Uniwersytet Gdanski

发明人： Kote, Sachin ,  Marek-Trzonkowska, Natalia ,  Czaplewska, Paulina ,  Müller, Marc ,  Pirog, Artur ,  Faktor, Jakub

IPC分类号： G01N33/50 ,  G01N33/68 ,  G01N1/34

CPC分类号： G01N33/5002 ,  G01N33/6842 ,  G01N33/6848 ,  G01N33/6893 ,  G01N2570/0020130101 ,  G01N2800/287120130101 ,  G01N1/34

摘要： The invention relates to the method for sample preparation for qualitative and quantitative analysis of peptidome in serum based on amino acid sequencing with a tandem mass spectrometry (MS) tool with signaling intensities measurement of peptides, characterized in that the method comprises the following steps: one step enrichment of peptides in the analyzed serum sample and removing of proteins equal or bigger than 15kDa from peptide enriched. The second invention is a data analysis workflow for quantitative analysis of the peptides sequenced with tandem mass spectrometry.