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    A MIXING SYSTEM INCLUDING FILLABLE 3D FLEXIBLE POUCH FOR BIOPHARMACEUTICAL FLUIDS, AND METHOD FOR IMPROVING MIXING IN SINGLE-USE BIOREACTORS
    3.
    发明公开
    A MIXING SYSTEM INCLUDING FILLABLE 3D FLEXIBLE POUCH FOR BIOPHARMACEUTICAL FLUIDS, AND METHOD FOR IMPROVING MIXING IN SINGLE-USE BIOREACTORS 审中-公开

    公开(公告)号：EP4108321A1

    公开(公告)日：2022-12-28

    申请号：EP21181542.8

    申请日：2021-06-24

    Applicant: SARTORIUS STEDIM FMT SAS

    Inventor： Summerton, Jim ,  LaVere, Dennis

    IPC: B01F7/16 ,  B01F15/00 ,  B01F3/12 ,  C12M1/02

    Abstract: Initially heterogenous biopharmaceutical composition is mixed in a bag (2) designed as a mixed bioreactor with capacity of at least 1500 liters, using an apparatus (1) that includes a tank (T), the flexible and collapsible bag (2) received in the tank and a stirring device (3). The device (3) comprise an impeller (13) driven from below for initiating agitation adjacent to a tank base (5). Once the bag is stretched under liquid pressure, it becomes parallelepiped with a bottom wall (2a), a top wall (2b) and a sidewall (2c). The bag, in contact against four side panels (15a, 15b, 15c, 15d) of the tank, has a rectangular cross section including four rounded corners each spaced from the side wall (15), with the following relationship satisfied:
    0.1
    where p is an inner perimeter at said base, r is a curvature radius d at the four rounded corners.

    UPGRADE SYSTEM FOR A MIXING PLANT, MIXING PLANT AND MONITORING METHOD
    7.
    发明公开
    UPGRADE SYSTEM FOR A MIXING PLANT, MIXING PLANT AND MONITORING METHOD 审中-公开

    公开(公告)号：EP4023406A1

    公开(公告)日：2022-07-06

    申请号：EP20425063.3

    申请日：2020-12-30

    Applicant: Tecno S.r.l.

    Inventor： Lombardi, Giovanni ,  Camerlingo, Giuseppe ,  Zanfardino, Angelo ,  Beneduce, Mauro

    IPC: B28C7/04 ,  B01F15/00 ,  G01G19/24

    Abstract: An updating system (1) for a mixing plant (10) comprising a reading device (2) configured to generate a load signal (S_C), a DIO converter (6) configured to read an open or closed state of each hopper (T1, T2, T3, T4) and generate an open (S_A) or closed (S_CL) signal of each hopper (T1, T2, T3, T4), a datalogger (8) configured to receive, process and store the load signals (S_C) and the open (S_A) or closed (S_CL) signals of each hopper (T1, T2, T3, T4) and a communication system (9) configured to send the signals (S_C, S_A, S_CL) processed and stored by the datalogger (8) to a server (C).

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