摘要:
Neutral copper complexes, particularly copper salicylate complexes having the formula Cu[C 6 H 4 (OH)COO] 2 γ in which y is dimethyl sulphoxide or dimethylformamide, have been found to have therapeutic activity in the treatment of inflammatory diseases and copper deficiency conditions. The complexes have been found particularly suitable for the treatment of Menkes' syndrome.
摘要:
Substituted formamides such as dimethyl formamide prepared by the catalytic oxidation of tertiary methyl-amines, in which the catalyst is cupric chloride or other metal halide used in conjunction with an alkali metal halide or ammonium halide adjunct. The use of the adjunct increases the solubility of the corrosive catalyst in the reaction medium, reducing the corrosion effects of the process on reaction equipment, and can also enhance selectivity.
摘要:
Formamides e.g. diethylformamide are prepared by reacting a primary or secondary amine e.g.diethylamine or ammonia with (a) an alkyl formate or (b) carbon monoxide and an alkanol in the presence, as catalyst, of (i) a compound containing an amide group or (ii) a Group V element-containing Lewis base and an epoxide. The Lewis base can be a trivalent nitrogen or phosphorus-containing compound. The amidine group which can be cyclic or acyclic can form part of a guanidine group.
摘要:
The alkali metal methylate catalyst used in the catalytic preparation of dimethylformamide from dimethylamine and carbon monoxide is deactivated after completion of the reaction by bringing it into contact with an alkyl formate.