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    AROMATIC DI-KETO DERIVATIVES AS GLUCOSE-6-PHOSPHATE TRANSLOCASE INHIBITORS
    1.
    发明公开
    AROMATIC DI-KETO DERIVATIVES AS GLUCOSE-6-PHOSPHATE TRANSLOCASE INHIBITORS 有权
    芳香二酮衍生物作为葡萄糖-6-磷酸酯转移酶抑制剂

    公开(公告)号：EP1248763A2

    公开(公告)日：2002-10-16

    申请号：EP00960495.0

    申请日：2000-08-19

    申请人： Aventis Pharma Deutschland GmbH

    发明人： VERTESY, Lászlo ,  KURZ, Michael ,  PAULUS, Erich

    IPC分类号： C07C63/42 ,  C07D493/20 ,  C07D307/20 ,  A61K31/19 ,  A61K31/40 ,  A61P3/10

    CPC分类号： C07C65/40 ,  C07D307/20

    摘要： The present invention relates to new aromatic di-keto derivatives and to their pharmaceutically acceptable salts, esters, ethers and other chemical equivalents. The derivatives are glucose-6-phosphate translocase inhibitors and can be used in the treatment of diabetes mellitus. The present invention further relates to a process for the production of the derivatives, to the use of the derivatives and their pharmaceutically acceptable salts, esters, ethers and other chemical equivalents as pharmaceuticals, in particular to their use in the treatment of diabetes mellitus, and to pharmaceutical compositions comprising the derivatives, pharmaceutically acceptable salts, esters, ethers or other chemical equivalents thereof.

    摘要翻译： 本发明涉及新的芳族二酮衍生物及其药学上可接受的盐，酯，醚和其他化学等价物。 衍生物是葡萄糖-6-磷酸转运酶抑制剂，可用于治疗糖尿病。 本发明进一步涉及生产该衍生物的方法，该衍生物及其药学上可接受的盐，酯，醚和其他化学等价物作为药物的用途，特别是其用于治疗糖尿病的用途，以及 涉及包含其衍生物，药学上可接受的盐，酯，醚或其他化学等同物的药物组合物。