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805 条记录 (耗时 0.019 秒)

    BETA-STRAND TYPE CROSSLINKED PEPTIDE
    6.
    发明公开
    BETA-STRAND TYPE CROSSLINKED PEPTIDE 审中-公开

    公开(公告)号：EP4238979A1

    公开(公告)日：2023-09-06

    申请号：EP21886412.2

    申请日：2021-10-29

    申请人： Xeno-Interface Inc. ,  Kyoto University

    发明人： HAYASHI, Kazuhiro ,  MATSUDA, Michiyuki

    IPC分类号： C07K4/00 ,  A61K38/02

    摘要： The present disclosure provides a novel bridge peptide. The present disclosure provides a bridge peptide comprising a bridge moiety and a peptide moiety, wherein position β is tertiary or quaternary when the carbon at which the bridge moiety attaches to the peptide moiety is in position α. The present disclosure provides a novel bridge peptide, particularly a bridge peptide resulting from stably bridging a peptide that does not possess a hydrogen bond to induce or maintain a secondary structure, e.g., a peptide having a β-strand structure.

    PEPTIDES DERIVED FROM MELANOMA-ASSOCIATED ANTIGEN B2 (MAGEB2)
    8.
    发明公开
    PEPTIDES DERIVED FROM MELANOMA-ASSOCIATED ANTIGEN B2 (MAGEB2) 审中-公开

    公开(公告)号：EP3974443A3

    公开(公告)日：2023-01-11

    申请号：EP21183259.7

    申请日：2016-11-23

    申请人： Immunocore Limited ,  Adaptimmune Limited

    发明人： POWLESLAND, Alex ,  CHESTER, Fiona

    IPC分类号： C07K14/47 ,  C07K4/12 ,  C07K7/06

    摘要： The present invention relates to novel peptides derived from Melanoma-associated antigen B2 (MAGEB2), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.