中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

338 records (took 0.016 seconds)

    PROCESS FOR PRODUCING A THERMOPLASTIC MATERIAL FOR USE AS A FILM OR AS A FLEXIBLE COATING
    2.
    发明公开
    PROCESS FOR PRODUCING A THERMOPLASTIC MATERIAL FOR USE AS A FILM OR AS A FLEXIBLE COATING 审中-公开

    公开(公告)号：EP4194485A1

    公开(公告)日：2023-06-14

    申请号：EP22212643.5

    申请日：2022-12-09

    Applicant: Traceless Materials GmbH

    Inventor： Lamp, Anne

    IPC: C08H1/00 ,  C08J5/18 ,  C08L89/00 ,  C08K5/053

    Abstract: A process for producing a thermoplastic material for use as a film or as a flexible coating, comprising the steps:
    i. mixing a biomass containing prolamins, such as a grain source for a water insoluble fraction of a grain), having prolamins and lipids, and an organic solvent to obtain undissolved components and dissolved components comprising dissolved prolamin, lipids, and other dissolved components
    ii. extracting said dissolved components into a first liquid phase and extracting undissolved components in a first solid phase under the following conditions:
    a. maintaining temperature T below 80°Celsius, preferably below 75°C, most preferably below 70°C
    b. maintaining dielectric constant ε r (at 25°C) between 30 and 42
    c. maintain pressure level p at below 2 bar
    d. performing extraction for no longer than an extraction time te (in min) = ke1 *T (in °C) + ke2* ε r (at 25°C) + ke3*p (bar absolute), wherein
    ke1 is in the range between 0.04 and 1.00
    ke2 is in the range between 0.08 and 2.00
    ke3 is in the range between 1.70 and 60.00

    iii. separating the first solid phase from the first liquid phase
    iv. precipitating a first fraction of said dissolved components out of the first liquid phase to obtain a second solid phase and a second liquid phase under the following conditions:
    a. a temperature drop during transforming the first liquid phase to the second liquid phase is provided for of at least 5°C, preferably at least 10°C, more preferably at least 15°C, at least 20°C, at least 25°C, at least 30°C, at least 35°C, at least 40°C, and most preferably at least 45°C.
    b. maintaining dielectric constant εr (at 25°C) between 30 and 42
    c. maintaining pressure level p at below 2 bar
    (iv) separating the second solid phase from the second liquid phase
    v. recovering said thermoplastic material from the second liquid phase by removing organic solvent under the following conditions:
    - maintaining temperature of the prolamins below 80°C, preferably below 75°C, most preferably below 70°C
    - maintaining a dielectric constant ε r (at 25°C) between 30 and 42
    - maintaining a pressure level at below bar
    - performing recovering for no longer than for no longer than a recovering time t (in min) = kr1*T (in °C) + kr2* (at 25°C) + kr3*p (bar absolute)
    where
    kr1 is in the range between 0.0004 and 12.0000
    kr2 is in the range between 0.0008 and 67.0000
    kr3 is in the range between 0.0167 and 80000.0000

    THIOL-MODIFIED POLYMER COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    3.
    发明公开
    THIOL-MODIFIED POLYMER COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 审中-公开

    公开(公告)号：EP4063399A1

    公开(公告)日：2022-09-28

    申请号：EP20889336.2

    申请日：2020-03-18

    Applicant: Blafar Biotechnology (Hangzhou) Ltd.

    Inventor： WANG, Wenxin

    IPC: C08B37/08 ,  C08G65/334 ,  C08H1/00 ,  C08F20/20 ,  C08F16/06 ,  C08F8/34

    Abstract: The present invention relates to a thiol-modified polymer compound, and a preparation method therefor and an application thereof. In the present invention, a polymer compound modified by an acryloyl derivative and a polythiol compound are used for preparing a thiol-modified polymer compound by a Michael addition reaction of thiol and conjugated double bonds. In addition to achieving the structural goal of the thiol-modified polymer compound provided in the present invention, the preparation method further has the following advantages: flexibly and effectively controlling the structure and constitution of a synthetic product, and the types and contents of a large number of compound molecular functional groups; using reagents having high biocompatibility, and effectively controlling the production cost and reducing the toxicity in the synthesis process; and obtaining, under the conditions of using safety reagents and simple reaction steps, thiol-modified biocompatible polymer compounds that can be used as extracellular matrix materials and maintain good raw material structure and biological activity, with the types and contents of functional groups adjusted according to requirements, and meeting multiple clinical application requirements.

    PREPARATION AND/OR FORMULATION OF PROTEINS CROSS-LINKED WITH POLYSACCHARIDES
    4.
    发明公开
    PREPARATION AND/OR FORMULATION OF PROTEINS CROSS-LINKED WITH POLYSACCHARIDES 审中-公开

    公开(公告)号：EP4043043A1

    公开(公告)日：2022-08-17

    申请号：EP22153746.7

    申请日：2011-11-22

    Applicant: Allergan Pharmaceuticals International Limited

    Inventor： Sommer-Knudsen, Jens

    IPC: A61L27/24 ,  A61L27/20 ,  C08H1/00 ,  A61K8/64 ,  A61L27/22 ,  A61L27/26

    Abstract: Therapeutic compositions and/or formulations are provided, comprising: at least one cross-linked protein matrix, wherein the at least one cross-linked protein matrix comprises at least one protein residue and at least one saccharide-containing residue, and methods of producing the same. The cross-linked protein matrix may be derived from cross-linking a full length or substantially full length protein, such as tropoelastin, elastin, albumin, collagen, collagen monomers, immunoglobulins, insulin, and/or derivatives or combinations thereof, with a saccharide containing cross-linking agent, such as a polysaccharide cross-linking agent derived from, for example, hyaluronic acid or a cellulose derivative. The therapeutic compositions may be administered topically or by injection. The present disclosure also provides methods, systems, and/or kits for the preparation and/or formulation of the compositions disclosed herein.

Patent Agency Ranking