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    DEVICES AND METHODS FOR SAMPLE ANALYSIS
    1.
    发明公开
    DEVICES AND METHODS FOR SAMPLE ANALYSIS 审中-公开

    公开(公告)号：EP4417691A3

    公开(公告)日：2024-11-13

    申请号：EP24172221.4

    申请日：2017-09-14

    申请人： Abbott Laboratories

    发明人： LAURENSON, Sophie ,  HAYDEN, Mark A. ,  HUFF, Jeffrey B. ,  FISCHER, Andrew ,  ROBINSON, John ,  HOLETS-MCCORMACK, Shelley R.

    IPC分类号： C12Q1/6853 ,  C07H21/02 ,  C12N15/09

    摘要： Integrated devices (30; 40; 100; 101; 600); that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. The detection modules disclosed here can be used for detecting analytes of interest which analytes may have been enriched by amplification, isolation, or other techniques.

    METHODS AND COMPOSITIONS FOR MANIPULATING NUCLEIC ACIDS
    7.
    发明公开
    METHODS AND COMPOSITIONS FOR MANIPULATING NUCLEIC ACIDS 审中-公开

    公开(公告)号：EP4403648A2

    公开(公告)日：2024-07-24

    申请号：EP24159800.2

    申请日：2020-04-30

    申请人： Life Technologies Corporation

    发明人： Rosenbaum, Abraham ,  Seeger, Collyn ,  Gray, Jeremy ,  Yu, Hua

    IPC分类号： C12Q1/6853

    CPC分类号： C12Q1/6853

    摘要： The present disclosure provides methods, compositions and kits as well as systems for manipulating nucleic acids, including implementing isothermal amplification, such as recombinase-polymerase amplification (RPA), of a nucleic acid template using a pre-seeded solid support. Provided are rapid and efficient methods for generating template nucleic acid molecules comprising specific nucleotide sequence bound to solid support. Such methods can be used, for example, in manipulating nucleic acids in preparation for analysis methods that utilize monoclonal populations of nucleic acids.