TRAPPING ION MOBILITY SPECTROMETER WITH PARALLEL ACCUMULATION

    公开(公告)号:EP3783638A1

    公开(公告)日:2021-02-24

    申请号:EP20184934.6

    申请日:2016-01-27

    摘要: The invention relates to the operation of trapping ion mobility spectrometers based on pushing ions by a gas flow against a counter-acting electric DC field barrier, preferably in combination with a mass analyzer as ion detector. The invention provides a linear RF ion trap upstream of the trapping ion mobility spectrometer, wherein the RF ion trap is operated as an accumulation unit in parallel with the trapping ion mobility spectrometer such that a first group of ions can be analyzed in the trapping ion mobility spectrometer while a second group of ions from an ion source are simultaneously collected in accumulation unit.

    ION MOBILITY ENHANCED QUALITATIVE AND QUANTITATIVE METHODS

    公开(公告)号:EP4258322A1

    公开(公告)日:2023-10-11

    申请号:EP23165404.7

    申请日:2023-03-30

    IPC分类号: H01J49/00 G01N27/622

    摘要: A system for analyzing a sample includes a source configured to generate ions from constituent components of the sample; a mobility separator configured to separate ions received from the source based on the mobility in a gas; a ion storage array configured to store ions from the mobility separator as a plurality of mobility fractions; a mass filter configured to select ions within a mass-to-charge window; a mass analyzer configured to determine the mass-to-charge ratio of the ions; and a controller. The controller is configured to identify an ion mobility fraction and a mass-to-charge window to select for a charge state or ion class; utilize the mass filter to select ions from the ion storage array within the mass-to-charge window corresponding to a charge state or ion class; and analyze the selected ions with the mass analyzer.