-
公开(公告)号:EP4378948A1
公开(公告)日:2024-06-05
申请号:EP22849616.2
申请日:2022-07-29
申请人: OSAKA UNIVERSITY
发明人: SHIRAKAMI, Yoshifumi , KANEDA, Kazuko , KADONAGA, Yuichiro , WATABE, Tadashi , TOYOSHIMA, Atsushi , FUKASE, Koichi , YOSHIYA, Taku
IPC分类号: C07K4/00 , A61K38/08 , A61K51/08 , A61P13/08 , A61P35/00 , C07B59/00 , C07C273/18 , C07C275/16 , C07F5/02 , G01T1/161
CPC分类号: A61K38/08 , A61K51/08 , A61P13/08 , A61P35/00 , C07B59/00 , C07C273/18 , C07C275/16 , C07F5/02 , C07K4/00 , G01T1/161
摘要: The aims of the present invention are to provide an agent that binds specifically to PSMA, is effective in the treatment and diagnosis of tumors or cancers expressing PSMA, for example, the treatment and diagnosis of prostate cancer, especially castration-resistant prostate cancer (CRPC), further especially metastatic castration-resistant prostate cancer (mCRPC), and does not exhibit side effects due to accumulation in the kidney or salivary glands.
The present invention provides a radiolabeled compound represented by Formula (I) or a pharmaceutically acceptable salt thereof:
wherein each symbol is as defined in the description.-
2.
公开(公告)号:EP4283343A1
公开(公告)日:2023-11-29
申请号:EP22742694.7
申请日:2022-01-21
申请人: RIKEN
摘要: To provide a system, a method, and a program whereby a reconstructed image supported by an algebraically exact solution of an inverse discrete Radon transform can be generated using fewer computational resources, and a recording medium in which the program is recorded. A computer-implemented method for determining an operating parameter of a tomographic imaging system for reconstructing a tomographic image by an inverse discrete Radon transform in a scan angle range of less than (180°-180°/number of projections), wherein the method includes: a step for determining a system matrix on the basis of the value of one or two operating parameters designated from among a number of detection elements, a number of projections, and a scan angle range less than (180°-180°/number of projections); a step for generating a square system matrix from the determined system matrix; a step for deciding whether an inverse matrix exists for the square system matrix; and a step for repeating said steps as necessary to determine the value of an operating parameter that corresponds to an operating parameter other than the designated one or two operating parameters, for which the inverse matrix of the square system matrix exists.
-
公开(公告)号:EP3793444B1
公开(公告)日:2023-10-11
申请号:EP18919116.6
申请日:2018-05-14
发明人: CAO, Peiyan , LIU, Yurun
-
公开(公告)号:EP3752864B1
公开(公告)日:2023-07-05
申请号:EP19840996.3
申请日:2019-07-23
发明人: KIM, Youngik , CHO, Minsik , KIM, Uncheol
-
公开(公告)号:EP4189441A1
公开(公告)日:2023-06-07
申请号:EP21746155.7
申请日:2021-07-14
-
-
-
8.
公开(公告)号:EP4113540A1
公开(公告)日:2023-01-04
申请号:EP21760171.5
申请日:2021-02-26
摘要: The present invention belongs to the field of imaging systems based on gamma ray detectors, such as gamma cameras, equipped with multi-pinhole collimators. More specifically, the invention relates to a planar-symmetry device for high-sensitivity gamma ray detection, which allows real-time tomography image reconstruction with very good spatial resolution. Advantageously, the multi-pinhole collimators of the device move during data collection and/or one or more of the pinholes thereof moves independently, thereby allowing possible artifacts resulting from overlap areas of the detector to be completely eliminated.
-
9.
公开(公告)号:EP4005487A1
公开(公告)日:2022-06-01
申请号:EP20844461.2
申请日:2020-07-22
申请人: FUJIFILM Corporation
发明人: KESHWANI, Deepak
摘要: A learning unit derives, from a target image including at least one tubular structure, in a case where an image for learning and ground-truth data of a graph structure included in the image for learning are input to an extraction model which extracts a feature vector of a plurality of nodes constituting a graph structure of the tubular structure, a loss between nodes on the graph structure included in the image for learning on the basis of an error between a feature vector distance between nodes belonging to the same graph structure and a topological distance which is a distance on a route of the graph structure between the nodes, and performs learning of the extraction model on the basis of the loss.
-
公开(公告)号:EP2967465B1
公开(公告)日:2022-04-13
申请号:EP13877838.6
申请日:2013-11-27
-
-
-
-
-
-
-
-
-