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公开(公告)号:EP4313010A1
公开(公告)日:2024-02-07
申请号:EP22712587.9
申请日:2022-03-14
申请人: Szekeres, Thomas , Jäger, Walter
发明人: Szekeres, Thomas , Jäger, Walter
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公开(公告)号:EP3517107B1
公开(公告)日:2023-11-01
申请号:EP17853177.8
申请日:2017-09-22
IPC分类号: A61K31/09 , A61P15/00 , A23L33/10 , A23L33/105
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3.
公开(公告)号:EP4205734A1
公开(公告)日:2023-07-05
申请号:EP21950502.1
申请日:2021-07-22
申请人: Sichuan University
发明人: MAO, Shengjun , GAO, Xiaofeng , LUO, Lijun , LI, Rui , ZHANG, Jian , YANG, Peng , ZHANG, Di , LIU, Qi , YANG, Huiyuan
摘要: The present invention provides an application of α-asarone in the preparation of a medicine for preventing or treating hemorrhagic strokes. α-asarone has the structure shown in formula I, and may significantly improve short-term neurological deficits and long-term learning and memory functions of model rats, reduce cerebral edema, improve the permeability of the blood-brain barrier, and prevent or mitigate the atrophy of brain tissue during a recovery period. α-asarone has a precise therapeutic effect on animal models of hemorrhagic stroke without obvious toxic side effects, and is expected to have great application prospects as a medicine for preventing/treating hemorrhagic strokes.
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4.
公开(公告)号:EP3307754B1
公开(公告)日:2022-09-14
申请号:EP16807940.8
申请日:2016-02-25
发明人: MARCOTULLI, Eric, Alexander , GUARENTE, Leonard, Pershing , ALMINANA, Daniel, Antonio , BOWEN, Paul, Michael
IPC分类号: C07H19/048 , A61K31/09 , A61K31/706 , A61P17/00 , A61P17/16 , A61K8/67 , A61K8/368 , A61K9/00
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公开(公告)号:EP3930728A1
公开(公告)日:2022-01-05
申请号:EP20763239.9
申请日:2020-02-25
发明人: ESTRELA ARIGÜEL, José María , OBRADOR PLA, María Elena , SALVADOR, Rosario , DELLINGER, Ryan W.
IPC分类号: A61K31/706 , A61K31/09 , A61K31/198 , A61K31/437 , A61P25/00
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公开(公告)号:EP3441064B1
公开(公告)日:2021-07-28
申请号:EP18188605.2
申请日:2018-08-11
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公开(公告)号:EP3836910A1
公开(公告)日:2021-06-23
申请号:EP19759863.4
申请日:2019-08-16
申请人: Baylor University
IPC分类号: A61K31/09 , A61K31/11 , A61K31/12 , A61K31/235 , A61K31/275 , C07C43/257 , A61P35/00 , C07C255/54 , C07C23/02
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公开(公告)号:EP3366303B1
公开(公告)日:2020-06-24
申请号:EP17158463.4
申请日:2017-02-28
IPC分类号: A61K38/18 , A61K31/09 , A61K31/337 , A61K31/513 , A61K31/675 , A61K31/704 , A61K31/7068 , A61K35/17 , A61K35/28 , A61P35/00 , A61P25/00 , A61P29/00
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公开(公告)号:EP2962688B1
公开(公告)日:2020-06-24
申请号:EP15172934.0
申请日:2010-05-12
申请人: Galenica AB
发明人: Hansson, Henri , Morén, Anna Karin
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公开(公告)号:EP2445488B1
公开(公告)日:2020-03-18
申请号:EP09846433.2
申请日:2009-07-30
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