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公开(公告)号：EP4431102A1
公开(公告)日：2024-09-18
申请号：EP22893206.7
申请日：2022-11-09
申请人： Lifeceutix Co., Ltd.
发明人： KIM, Tae Kook , JANG, Hyung Ju , CHOO, Kang Sik
IPC分类号： A61K31/714 , A61K31/095 , A61K31/28 , A61K31/5025 , A61P43/00 , A61P35/00 , A61P17/00 , A61K38/44 , G01N33/50
CPC分类号： A61K31/095 , A61K31/28 , A61K31/381 , A61K31/4035 , A61K31/4164 , A61K31/437 , A61K31/454 , A61K31/472 , A61K31/496 , A61K31/5025 , A61K31/53 , A61K31/7135 , A61K31/714 , A61K38/44 , A61K45/06 , A61P17/00 , A61P35/00 , A61P43/00 , G01N33/50
摘要： The present disclosure provides a composition for removing senescent cells that is useful in senescent cell removal. The composition of the present invention induces the death of senescent cells and thus can be usefully applied to the amelioration, treatment, or prevention of various aging-associated diseases and disorders caused by senescent cells. In addition, the composition of the present invention can be usefully applied as pharmaceuticals, cosmetics, health functional foods, animal products, etc. in relation to aging-associated diseases and disorders caused by senescent cells.
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公开(公告)号：EP3615013B1
公开(公告)日：2024-08-14
申请号：EP18724662.4
申请日：2018-04-24
IPC分类号： A61K31/095 , A61K31/198 , A61K31/397 , A61K31/4035 , A61K31/404 , A61K31/407 , A61K31/415 , A61K31/445 , A61K31/506 , A61P25/28
CPC分类号： A61K31/095 , A61K31/198 , A61K31/397 , A61K31/4035 , A61K31/404 , A61K31/407 , A61K31/415 , A61K31/445 , A61K31/506 , A61P25/08 , A61K31/145 , A61K31/40 , A61K31/44
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公开(公告)号：EP4392397A2
公开(公告)日：2024-07-03
申请号：EP22862274.2
申请日：2022-08-25
申请人： AbbVie Inc.
发明人： KU, Yi-yin , GRIEME, Timothy , HARPER, Kaid , JIN, Ji-an , MACK, Daniel , MAREK, James , MOSCHETTA, Eric , PATEL, Ketan , PU, Yu-ming , SACIA, Eric , TOWNE, Timothy
IPC分类号： C07C17/269 , A61K31/03 , A61K31/095
CPC分类号： C07C319/14 , C07C315/02 , C07C317/14 , C07D295/13 , C07D295/155 , C07C51/412
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公开(公告)号：EP3962468B1
公开(公告)日：2024-02-14
申请号：EP20724543.2
申请日：2020-04-29
IPC分类号： A61K31/095 , C07C317/14 , A61K31/277 , C07C317/44
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公开(公告)号：EP3849343B1
公开(公告)日：2023-07-12
申请号：EP18769342.9
申请日：2018-09-12
IPC分类号： A23L33/10 , A61K36/906 , A61K36/9066 , A61K31/095 , A61K31/724 , A61K36/02 , A61K36/67 , A23L33/105 , A23L33/135 , A23L33/15 , A23L33/22 , A61K31/12 , A61K31/375 , A61K31/4525 , A61K36/03 , A61K36/9068
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6.发明公开
公开(公告)号：EP4149487A1
公开(公告)日：2023-03-22
申请号：EP21732623.0
申请日：2021-05-13
申请人： Probioticsmart, LLC
发明人： DUBOURDIEU, Daniel J. , LALL, Rajiv
IPC分类号： A61K31/7135 , A61P29/00 , A61P35/00 , A61K31/095 , C07F3/00
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公开(公告)号：EP3302507B1
公开(公告)日：2023-02-22
申请号：EP16800846.4
申请日：2016-05-27
发明人： BOT, Adrian , WIEZOREK, Jeffrey S. , GO, William , JAIN, Rajul , KOCHENDERFER, James N. , ROSENBERG, Steven A.
IPC分类号： A61K35/17 , A61K38/20 , C12N5/0783 , C12N5/10 , C12N15/19 , C12N15/24 , A61K31/00 , C07K14/52 , C07K14/00 , C12N15/00 , G01N33/68 , A61P35/00 , A61K31/095 , A61K31/445 , A61K31/52 , A61K31/665 , A61K39/00 , C07K14/725
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8.发明授权
公开(公告)号：EP3449943B1
公开(公告)日：2022-08-31
申请号：EP18192176.8
申请日：2018-09-03
IPC分类号： A61K31/164 , A61K45/06 , A61K31/235 , A61K31/352 , A61K31/353 , A61K31/7048 , A61K31/593 , A61P13/12 , A61K31/095 , A61K31/16 , A61K31/355 , A61K31/451
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9.发明公开
公开(公告)号：EP3827816A1
公开(公告)日：2021-06-02
申请号：EP19212199.4
申请日：2019-11-28
发明人： MOOSMANN, Bernd
IPC分类号： A61K31/095 , A61K31/10 , A61K31/275 , A61P33/00 , A61P33/02 , A61P35/00
摘要： The present invention relates to prooxidative chain-transfer agents for use in the treatment of a malignant tumour disease, or infectious disease. The prooxidative chain-transfer agents are selected from lipophilic thiols, lipophilic trithiocarbonates, lipophilic, aromatic dithioesters, and lipophilic, aromatic thiols. The compounds amplify the prooxidative activity at the target site and are therefore highly efficient and specific for their targets.
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公开(公告)号：EP3122342B1
公开(公告)日：2020-09-23
申请号：EP15770142.6
申请日：2015-03-27
IPC分类号： C07C319/12 , C07C323/59 , C07C323/60 , A61K31/095 , A61K31/16 , A61K31/195 , A61K31/198 , A61K38/04
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