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    DRUG USED FOR TREATING TISSUE NECROSIS OR FOR IMPROVING CARDIAC FUNCTION
    2.
    发明公开
    DRUG USED FOR TREATING TISSUE NECROSIS OR FOR IMPROVING CARDIAC FUNCTION 审中-公开

    公开(公告)号：EP3834834A1

    公开(公告)日：2021-06-16

    申请号：EP19847075.9

    申请日：2019-08-09

    申请人： Zhejiang Hygeiancells Biomedical Co. Ltd

    发明人： QIAN, Jin ,  SUN, Ning ,  GAO, Xiang ,  CUI, Baiping ,  ZHENG, Yufan

    IPC分类号： A61K35/57 ,  A61K9/19 ,  A61K9/10 ,  A61P9/10

    摘要： A drug used for treating ischemia and hypoxia-induced tissue necrosis or for improving cardiac function; the drug contains amniotic fluid from a non-human animal and/or an extract thereof, and an optional pharmaceutically acceptable carrier, wherein the amniotic fluid comes from chicken eggs having an embryonic age of 5-12 days, eggs from other birds corresponding to the described developmental period, embryos from rodents having a gestational age of 8-20 days, or embryos from other non-human mammals corresponding to the described developmental period. The drug may promote the growth of human umbilical vein endothelial cells, AC16 cells and chicken embryo fibroblasts, improve cardiac function after myocardial infarction, and promote cardiac cell regeneration after a myocardial infarction.

    MEDICINE FOR PREVENTING OR TREATING ENTERITIS AND INTESTINAL CANCER
    7.
    发明公开
    MEDICINE FOR PREVENTING OR TREATING ENTERITIS AND INTESTINAL CANCER 审中-实审

    公开(公告)号：EP4424317A1

    公开(公告)日：2024-09-04

    申请号：EP22886104.3

    申请日：2022-10-28

    申请人： Anhui Hygeiancells Biomedical Co. Ltd

    发明人： QIAN, Jin ,  LI, Shiyan ,  WANG, Rong

    IPC分类号： A61K35/57 ,  A61P1/00

    CPC分类号： Y02A50/30 ,  A61P1/00 ,  A61K35/57

    摘要： Provided is a medicine for preventing or treating enteritis and intestinal cancer. Specifically, the present invention relates to a use of amniotic fluid in the preparation of a medicine for treating or preventing enteritis in a subject, a use in the preparation of a medicine for preventing intestinal cancer in a subject, and a use in the preparation of a medicine for activating Nrf2 and inhibiting NF-κB to reduce inflammation and oxidative damage caused by damage to the intestinal mucosa barrier of a subject; the amniotic fluid comes from eggs at embryo ages of 5-12 days, eggs from birds other than chickens at the development stage corresponding to the development stage of chickens at said embryo age, embryos of rodents at a gestational age of 8-14 days, or embryos of non-human mammals other than rodents at the development stage corresponding to the development stage of rodents at a gestational age of 8-14 days.