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公开(公告)号:EP4461313A1
公开(公告)日:2024-11-13
申请号:EP23737284.2
申请日:2023-01-04
申请人: Fujiwara, Hiroshi
发明人: Fujiwara, Hiroshi
IPC分类号: A61K45/00 , A61K39/395 , A61K47/68 , A61P35/00 , A61P35/02 , A61P35/04 , C07K14/47 , C07K16/28 , C07K16/40 , C12Q1/02
摘要: A pharmaceutical composition for treatment of cancer, comprising a substance binding to laeverin; a method for assessing cancer recurrence and/or metastasis; a method for determining a substance impairing a cancer cell expressing laeverin; a method for determining a factor influencing cancer recurrence and/or metastasis; and a use of laeverin as a biomarker for a cancer stem cell.
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公开(公告)号:EP4457341A1
公开(公告)日:2024-11-06
申请号:EP22915380.4
申请日:2022-10-18
发明人: SHARMA, Amit , CHOWDHURY, Debabani Roy , SHARMA, Garima , ROY, Samrat , PANDRE, Manoj , LEE, Soo-Woong , PARK, ChangWook , KUMAR RK, Rajesh , KANNAN, Sundarajan , CHOWDHURY, Arnab Roy
IPC分类号: C12N5/10 , A01K67/027 , C12N15/85 , A61P35/04
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公开(公告)号:EP4452962A1
公开(公告)日:2024-10-30
申请号:EP22912311.2
申请日:2022-12-15
发明人: CANDITO, David, A. , CHILDERS, Matthew, A. , DEMONG, Duane, E. , FISCHER, Christian , FRADERA, Xavier , JEWELL, James, P. , KAWAMURA, Shuhei , LIU, Ping , YEUNG, Charles, S. , ZHENG, Xiao Mei , LOGAN, Kaitlyn Marie , OTTE, Ryan, D. , HUANG, Chunhui , SCHNEIDER, Sebastian, E.
IPC分类号: C07D333/52 , A61K31/381 , A61P35/04
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公开(公告)号:EP3793573B1
公开(公告)日:2024-10-23
申请号:EP19803497.7
申请日:2019-05-14
发明人: DIPIERRO, Guy , DOS SANTOS, Gary
IPC分类号: A61K35/17 , A61P35/02 , A61P35/04 , C12N5/0783 , C12Q1/68 , C12Q1/6827 , C07K14/705
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公开(公告)号:EP4444757A2
公开(公告)日:2024-10-16
申请号:EP22905403.6
申请日:2022-12-09
发明人: FRIDMAN, Arthur , HANDA, Masahisa , HSIEH, Chung-Ming , SINGH, Sujata , TABRIZIFARD, Sahba , VANEGAS, Sandra, Isabel
IPC分类号: C07K16/30 , A61K39/395 , A61P35/04
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公开(公告)号:EP4434551A1
公开(公告)日:2024-09-25
申请号:EP23163555.8
申请日:2023-03-22
申请人: Nuske, Andreas
IPC分类号: A61K51/00 , A61P35/00 , A61P35/04 , G01N33/574 , A61K101/02
CPC分类号: A61K51/00 , A61K2121/0020130101 , A61K2123/0020130101 , A61P35/00 , A61P35/04
摘要: The present invention relates to a method for diagnosing and/or treating sodium-iodide symporter (NIS)-expressing primary carcinomas and metastases, preferably glandular carcinomas, in particular carcinomas of the thyroid, of the salivary gland, of the uterus and carcinomas of the breast, and to a pharmacological composition comprising substances which induce and/or increase the expression or function of the NIS symporter and, as a consequence, increase iodide uptake into the cells, and to corresponding uses. This can be used for an efficient tumor-specific radioiodide uptake in diagnosis and therapy of said carcinomas and metastases.
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公开(公告)号:EP4433174A1
公开(公告)日:2024-09-25
申请号:EP22896525.7
申请日:2022-11-18
IPC分类号: A61P35/04 , A61K36/9066 , A61K31/56 , A61K9/20 , A23L33/105
CPC分类号: A23L33/105 , A61K36/9066 , A61P35/04 , A23L33/10 , A61K31/12 , A61K31/19
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公开(公告)号:EP3212245B1
公开(公告)日:2024-09-11
申请号:EP15786941.3
申请日:2015-10-27
IPC分类号: A61L27/10 , A61L27/54 , A61L27/56 , A61K31/498 , A61P19/00 , A61P35/00 , A61P35/04 , C04B38/06
CPC分类号: A61L27/105 , A61K9/0024 , A61K31/498 , A61L27/56 , A61L2430/0220130101 , A61L27/54 , A61P19/00 , A61P35/00 , A61P35/04 , C04B38/0615 , C04B2111/0083620130101
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9.
公开(公告)号:EP4419565A1
公开(公告)日:2024-08-28
申请号:EP22884668.9
申请日:2022-10-19
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公开(公告)号:EP4419143A1
公开(公告)日:2024-08-28
申请号:EP22884675.4
申请日:2022-10-19
IPC分类号: A61K39/395 , A61K38/20 , A61P35/04 , C07K16/30 , C12N9/64
CPC分类号: A61P35/04 , C07K14/55 , A61K2039/515620130101 , A61K38/2013 , A61K38/20 , A61K38/191 , A61K38/193 , A61K38/21 , A61K2035/12820130101
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