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公开(公告)号：EP4442278A2
公开(公告)日：2024-10-09
申请号：EP24190375.6
申请日：2019-11-25
申请人： Forty Seven, Inc.
发明人： LIU, Jie , SOMPALLI, Kavitha
IPC分类号： A61K39/395
CPC分类号： C07K16/2803 , C07K2317/2420130101 , C07K2317/56520130101 , C07K2317/73220130101 , C07K2317/9220130101
摘要： The invention provides antibodies specifically binding to c-Kit and methods of using such antibodies in stem cell replacement and treatment of cancer.
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公开(公告)号：EP4434541A2
公开(公告)日：2024-09-25
申请号：EP24188851.0
申请日：2020-01-23
发明人： KOIDE, Shohei , MILLER, George , KOIDE, Akiko , PANCHENKO, Tatyana , HATTORI, Takamitsu , FILIPOVIC, Aleksandra , ELENKO, Eric , BOLEN, Joseph
IPC分类号： A61K39/00
CPC分类号： C07K16/2809 , C07K2317/5520130101 , C07K2317/3320130101 , C07K2317/9220130101 , C07K2317/5220130101 , C07K2317/9420130101 , C07K2317/73220130101 , C07K2317/7320130101 , C07K2317/7620130101 , A61K2039/50720130101 , A61K2039/50520130101
摘要： Disclosed herein are antibodies specific to a delta-1 chain of a γδ T cell receptor and methods of using such for modulating γδ T cell bioactivity. Such anti-Delta1 antibodies may also be used to treat diseases associated with γδ T cell activation, such as solid tumors, or for detecting presence of γδ1 T cells.
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公开(公告)号：EP4433510A1
公开(公告)日：2024-09-25
申请号：EP22894755.2
申请日：2022-11-15
申请人： Suzhou Transcenta Therapeutics Co., Ltd. , Transcenta Holding Limited , Transcenta Therapeutics, Inc.
发明人： QIAN, Xueming , YAO, Xinlai , GUO, Huanhuan , TENG, Fei , YI, Wei
IPC分类号： C07K16/28 , A61P35/00 , A61K39/395
CPC分类号： C07K16/28 , A61P35/00 , C07K2317/56520130101 , C07K16/2818 , A61K2039/50720130101 , A61K39/3955 , A61K31/555 , C07K2317/73220130101 , C07K16/2827 , A61K45/06
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4.发明公开
公开(公告)号：EP4426730A1
公开(公告)日：2024-09-11
申请号：EP22826723.3
申请日：2022-11-07
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公开(公告)号：EP4426439A1
公开(公告)日：2024-09-11
申请号：EP22817524.6
申请日：2022-11-03
申请人： Affimed GmbH
CPC分类号： C07K2317/73220130101 , C07K2317/3320130101 , C07K2317/9220130101 , C07K2317/3120130101 , C07K2317/62220130101 , C07K2317/52620130101 , A61K2039/50520130101 , C07K2317/9020130101 , C07K16/283 , C07K16/2866 , A61P35/02 , C07K2317/5220130101 , C07K2317/56520130101 , C07K2317/56720130101 , C07K2317/6420130101
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公开(公告)号：EP4417624A2
公开(公告)日：2024-08-21
申请号：EP24172994.6
申请日：2014-01-31
发明人： DAVIS, Samuel , SMITH, Eric , PATEL, Supriya , RAFIQUE, Ashique
IPC分类号： C07K16/28
CPC分类号： C07K16/2887 , C07K2317/3120130101 , C07K16/46 , C07K2317/2420130101 , C07K2317/5220130101 , C07K2317/7120130101 , C07K2317/73220130101 , C07K2317/73420130101 , C07K2317/9420130101 , C07K16/2809 , A61P43/00
摘要： Antibodies, antigen-binding proteins and Fc-fusion proteins that comprise recombinant polypeptides containing a chimeric heavy chain constant region sequence are provided that bind to certain Fc receptors however have reduced effector functions. Methods of making constructs for expression of such chimeric Fc-containing antibodies, antigen-binding proteins and Fc-fusion proteins in cell systems, and methods of producing and isolating the chimeric Fc-containing proteins are provided.
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公开(公告)号：EP3765502B1
公开(公告)日：2024-08-07
申请号：EP19709954.2
申请日：2019-03-13
IPC分类号： C07K16/28 , C07K14/55 , A61K39/00 , C07K14/715
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公开(公告)号：EP4396230A1
公开(公告)日：2024-07-10
申请号：EP22776886.8
申请日：2022-09-02
发明人： AMANN, Maria , POUSSE, Laurène , BOETSCH, Christophe , WEISSER, Martin , KOLBEN, Theresa , KARANIKAS, Vaios , ECKMANN, Jan , CARNEIRO DE MEDEIROS, Bruno
IPC分类号： C07K16/28 , A61P35/02 , A61P35/00 , A61K39/395 , A61K39/00
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公开(公告)号：EP4396221A1
公开(公告)日：2024-07-10
申请号：EP22777912.1
申请日：2022-08-31
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