公开(公告)号：JP2001097956A

公开(公告)日：2001-04-10

申请号：JP2000223499

申请日：2000-07-25

申请人： DU PONT

发明人： BARNETTE WILLIAM E ,  HARRISON CHARLES R ,  LAHM GEORGE P ,  PIOTROWSKI DAVID W ,  WING KEITH D

IPC分类号： A01N47/34 ,  A01N47/38 ,  C07C251/84 ,  C07C281/12 ,  C07C313/02 ,  C07C313/08 ,  C07D237/24 ,  C07D237/26 ,  C07D253/08 ,  C07D253/10 ,  C07D273/04 ,  C07D285/16 ,  C07D471/04 ,  C07D491/04 ,  C07D491/052

摘要： PROBLEM TO BE SOLVED: To provide a compound having an excellent arthropod-killing activity, and to provide an arthropod-killing agent containing the compound as an active ingredient. SOLUTION: A compound of formula (I) [Q is a group of formula (II) (R1 and R2 are each Cl, Br, CF3, OCF3, OCF2H, OSO2CF3 or the like; Y is NR6R7, N=CR8R9 or OR6; Z is selected from the group of CH2, O, S and NR6; R3, R6, R7, R8 and R9 are each H, an alkyl, a haloalkyl, phenyl substituted by a halogen or an alkoxy, or the like)].

公开(公告)号：JPH1067762A

公开(公告)日：1998-03-10

申请号：JP13116197

申请日：1997-05-21

申请人： HOECHST AG

发明人： WAGNER ADALBERT DR ,  HEITSCH HOLGER DR ,  NOELKEN GERHARD DR ,  WIRTH KLAUS DR ,  SCHOELKENS BERNWARD PROF DR

IPC分类号： C07D277/60 ,  A61K31/38 ,  A61K31/395 ,  A61K31/41 ,  A61K31/425 ,  A61K31/428 ,  A61K31/53 ,  A61P43/00 ,  C07D253/10 ,  C07D277/62 ,  C07D277/64 ,  C07D277/66 ,  C07D277/68 ,  C07D277/70 ,  C07D277/74 ,  C07D277/82 ,  C07D417/12

摘要： PROBLEM TO BE SOLVED: To produce a sulfur-containing compound which is a strong bradykinin antagonist and useful for treating and/or preventing allergies, inflammations, autoimmune diseases, shocks and pains. SOLUTION: This compound is represented by formula I one of X1 to X3 is C-O-R [R is a group represented by formula II (R and R are each H, a halogen, CN, etc.; R is H, a 1-5C alkyl, etc.; A is an aminocarboxyluc acid; R is H, etc.)]; others and X4 are N or CR (R is H, a halogen, etc.); R is same as R } and its physiologically permissible salt, e.g. 4-[3-(N-(3- methoxycinnamoylglycyl)-N-methylamino)-2,6-dichlorobenzyloxy]benzothia zole. The compound represented by formula I can be produced by passing a compound represented by formula III as a starting raw material through specific steps. Thereby, a pharmaceutical preparation for treating and/or preventing diseases caused by a mediator such as prostaglandins or leukotrienes.

公开(公告)号：JPH09510197A

公开(公告)日：1997-10-14

申请号：JP52328695

申请日：1995-02-27

IPC分类号： A01N33/22 ,  A01N41/10 ,  A01N43/06 ,  A01N43/08 ,  A01N43/10 ,  A01N43/40 ,  A01N43/50 ,  A01N43/54 ,  A01N43/56 ,  A01N43/58 ,  A01N43/60 ,  A01N43/64 ,  A01N43/66 ,  A01N43/707 ,  A01N43/713 ,  A01N43/74 ,  A01N43/76 ,  A01N43/80 ,  A01N43/82 ,  A01N43/824 ,  A01N43/836 ,  A01P5/00 ,  A01P7/02 ,  A01P7/04 ,  C07C17/087 ,  C07C17/23 ,  C07C317/14 ,  C07C323/05 ,  C07C323/09 ,  C07D213/70 ,  C07D213/71 ,  C07D213/80 ,  C07D213/81 ,  C07D213/82 ,  C07D213/84 ,  C07D213/85 ,  C07D231/18 ,  C07D231/28 ,  C07D231/30 ,  C07D233/84 ,  C07D233/86 ,  C07D233/90 ,  C07D233/92 ,  C07D237/10 ,  C07D237/18 ,  C07D237/30 ,  C07D241/12 ,  C07D241/18 ,  C07D241/44 ,  C07D251/22 ,  C07D253/04 ,  C07D253/06 ,  C07D253/07 ,  C07D253/075 ,  C07D253/10 ,  C07D257/04 ,  C07D261/10 ,  C07D261/14 ,  C07D261/18 ,  C07D263/34 ,  C07D263/46 ,  C07D271/06 ,  C07D271/07 ,  C07D271/10 ,  C07D271/113 ,  C07D275/02 ,  C07D275/03 ,  C07D277/20 ,  C07D277/36 ,  C07D277/40 ,  C07D277/56 ,  C07D277/58 ,  C07D285/08 ,  C07D285/12 ,  C07D285/125 ,  C07D285/135 ,  C07D307/64 ,  C07D333/34 ,  C07D333/36 ,  C07D333/38 ,  C07D333/62 ,  C07D409/04 ,  C07D413/04 ,  C07D417/04 ,  C07D471/04

摘要： A compound having the formula R-S(O)nCH2CH2CH=CF2, wherein R is a phenyl group or a heterocyclic group selected from furyl, thienyl, isoxazolyl, isothiazolyl, oxazolyl, thiazolyl, imidazolyl, pyrazolyl, 1,2,4-oxadiazolyl, 1,2,4-thiadiazolyl, 1,3,4-oxadiazolyl, 1,3,4-thidiazolyl, tetrazolyl, pyridyl, pyridazinyl, pyrazinyl, 1,2,3-triazinyl, 1,3,4-triazinyl, and 1,3,5-triazinyl groups, said phenyl or heterocyclic group being optionally substituted by optionally substituted alkyl, optionally substituted alkenyl, alkynyl, cycloalkyl, alkylcycloalkyl, alkoxy, alkenyloxy, alkynyloxy, hydroxyalkyl, alkoxyalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroaryl, optionally substituted heteroarylalkyl, optionally substituted aryloxy, optionally substituted arylalkoxy, optionally substituted aryloxyalkyl, optionally substituted heteroaryloxy, optionally substituted heteroarylalkoxy, optionally substituted heteroaryloxyalkyl, haloalkyl, haloalkenyl, haloalkynyl, haloalkoxy, haloalkenyloxy, haloalkynyloxy, halogen, hydroxy, cyano, nitro, -NR7R8, -NR7COR8, -NR7CSR8, -NR7SO2R8, -N(SO2R7)(SO2R8), -COR7, -CONR7R8, -alkylCONR7R8, -CR7NR8, -COOR7, -OCOR7, -SR7, -SOR7, -SO2R7, -alkylSR7, -alkylSOR7, -alkylSO2R7, -OSO2R7, -SO2NR7R8, -CSNR7R8, -SiR7R8R9, -OCH2CO2R7, -OCH2CH2CO2R7, -CONR7SO2R8, -alkylCONR7SO2R8, -NHCONR7R8, -NHCSNR7R8, or an adjacent pair of R1, R2, R3, R4, R5 and R6 when taken together form a fused 5- or 6-membered carbocyclic or heterocyclic ring; R7, R8 and R9 are each independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, alkynyl, optionally substituted aryl or optionally substituted arylalkyl, haloalkyl, haloalkenyl, haloalkynyl, halogen or hydroxy.

公开(公告)号：JPH08504783A

公开(公告)日：1996-05-21

申请号：JP51476594

申请日：1993-12-15

IPC分类号： C07D253/08 ,  A61K31/53 ,  A61P29/00 ,  A61P37/08 ,  C07D251/08 ,  C07D253/10

公开(公告)号：JPH05500499A

公开(公告)日：1993-02-04

申请号：JP51066589

申请日：1989-09-18

申请人： STANFORD RES INST INT

发明人： LEE WILLIAM W ,  BROWN J MARTIN ,  GRANGE EDWARD W ,  MARTINEZ ABELARDO P ,  TRACY MICHAEL ,  POLLART DANIEL J

IPC分类号： A61K31/53 ,  A61K31/535 ,  A61K41/00 ,  A61P35/00 ,  C07D20060101 ,  C07D253/08 ,  C07D253/10

公开(公告)号：JPH0430393B2

公开(公告)日：1992-05-21

申请号：JP23774683

申请日：1983-12-16

IPC分类号： C07D253/08 ,  C07D253/10 ,  G03C1/42 ,  G03C5/29 ,  G03C5/30 ,  G03C8/36

摘要： Dihydro-benzotriazine compounds of formula … … wherein R is H, alkyl, alkoxy or aryl, R1 is H, alkyl, -CF3, -COOH, -NH2, NHSO2R2 or -OR2, and R2 is alkyl, any alkyl or alkoxy groups preferably having from 1 to 6 carbon atoms, are of use as photographic silver halide developing agents in acid environment as well as in basic environment. Novel dihydro-benzotriazine compounds and photographic processes products and compositions utilising the developing agents are described.

公开(公告)号：JPS5636471A

公开(公告)日：1981-04-09

申请号：JP11990580

申请日：1980-09-01

申请人： ICI AUSTRALIA LTD

发明人： AREKISANDAA SAABAN ,  GUREEMU JIYON FUAAKARUSON ,  JIYATSUKU RIDEIATE ,  GURAHAMU JIYON BAADO

IPC分类号： C07D253/08 ,  A01N43/707 ,  C07D253/10

公开(公告)号：JPS55127379A

公开(公告)日：1980-10-02

申请号：JP3420380

申请日：1980-03-19

申请人： BAYER AG

发明人： KURAUSU ZATSUSE ,  INGO HARAA ,  MANFURETSUDO PUREMUPERU ,  HANSUUYOAHIMU TSUAIRAA ,  KARURU GEORUGU METSUGAA

IPC分类号： A61K31/50 ,  A61K31/53 ,  A61P31/04 ,  C07D253/08 ,  C07D253/10

公开(公告)号：JPS54112884A

公开(公告)日：1979-09-04

申请号：JP404179

申请日：1979-01-19

申请人： BAYER AG

发明人： KURAUSU ZAASE ,  BUARUTERU GAUSU ,  PAURUUERUNSUTO FUROOBERUGERU ,  PEETERU KURAUSU ,  FUORUKERU PAURU

IPC分类号： A01N43/64 ,  A01N43/707 ,  C07D253/08 ,  C07D253/10 ,  C07D403/04 ,  C07D521/00

公开(公告)号：JPS5231085A

公开(公告)日：1977-03-09

申请号：JP10176776

申请日：1976-08-27

申请人： BAYER AG

发明人： KURAUSU ZATSUSE ,  PAURU ERUNSUTO FUROOBERUGERU ,  HANSU SHIYAINPUFURUUKU

IPC分类号： C07D253/08 ,  A01N43/707 ,  A01P1/00 ,  A01P3/00 ,  C07D253/10