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2653 条记录 (耗时 0.04 秒)

    Method for producing extract containing 5'-deoxy-5'-methylthioadenosine
    83.
    发明专利
    Method for producing extract containing 5'-deoxy-5'-methylthioadenosine 有权
    生产含有5'-脱氧-5'-甲基二氢卟吩的提取物的方法

    公开(公告)号：JP2012184177A

    公开(公告)日：2012-09-27

    申请号：JP2011046973

    申请日：2011-03-03

    申请人： Cci Corp ,  シーシーアイ株式会社

    发明人： MURASE HIRONORI ,  MORITA KAZUTAKA

    IPC分类号： A61K36/07 ,  A61K31/7076 ,  A61P3/04 ,  A61P3/06 ,  A61P3/08 ,  A61P3/10 ,  A61P43/00 ,  C07H19/167 ,  C12N9/42 ,  C12P19/40

    CPC分类号： Y02P20/52

    摘要： PROBLEM TO BE SOLVED: To provide a method for elucidating that what component of mushroom extract has a PPARγ activation potency and efficiently extracting an active ingredient.SOLUTION: The method for producing an extract containing 5'-deoxy-5'-methylthioadenosine includes: (1) a step of adding water in an amount of 0.5-50 times the mass of mushroom mass to mushroom, grinding the mushroom to give ground mushroom, then heating the ground mushroom to perform sterilization and to partially decompose mushroom tissue and obtaining heated ground mushroom, and (3) a step of heating the heated ground mushroom to 40-121°C to perform hot water extraction and obtaining a mushroom extract.

    摘要翻译： 要解决的问题：提供一种阐明蘑菇提取物的组分具有PPARγ活化能力并有效提取活性成分的方法。 解决方案：含有5'-脱氧-5'-甲硫基腺苷的提取物的制造方法包括：（1）向蘑菇中加入量为蘑菇质量的0.5〜50倍的水的步骤，研磨蘑菇 给研磨蘑菇，然后加热地面蘑菇进行灭菌，并部分分解蘑菇组织并获得加热的研磨蘑菇，（3）将加热的地面蘑菇加热至40-121℃进行热水提取和获得 蘑菇提取物。 版权所有（C）2012，JPO＆INPIT

    Promoter for production and secretion of antimicrobial substance
    84.
    发明专利
    Promoter for production and secretion of antimicrobial substance 有权
    促进生产和分解抗微生物的物质

    公开(公告)号：JP2012180329A

    公开(公告)日：2012-09-20

    申请号：JP2011045604

    申请日：2011-03-02

    申请人： Hokkaido Univ ,  Three-B Co Ltd ,  国立大学法人北海道大学 ,  株式会社スリービー

    发明人： AYABE TOKIYOSHI ,  NAKAMURA KIMINORI ,  YOSHINARI ATSUSHIRO ,  ISHIDA MAKI

    IPC分类号： A61K36/07 ,  A61K31/4172 ,  A61P31/04 ,  A61P43/00

    CPC分类号： Y02A50/473

    摘要： PROBLEM TO BE SOLVED: To provide a promoter for production and secretion of antimicrobial substances in a Paneth cell, which promoter uses extracts from mushrooms and ergothioneine as active constituents.SOLUTION: The promoter for production and/or secretion of antimicrobial substances in a Paneth cell is provided, which promoter uses extracts from mushrooms and/or ergothioneine extracted from the mushrooms as active constituents. The promoter for production and/or secretion of antimicrobial substances uses extracts from edible mushrooms and ergothioneine as active constituents and has high safety. Also, the promoter for production and secretion of antimicrobial substances promotes the production and secretion of antimicrobial substances in a Paneth cell in a living body, so that immunization in the living body can be activated and also diseases can be prevented and treated.

    摘要翻译： 要解决的问题：提供Paneth细胞中抗微生物物质的生产和分泌促进剂，该启动子使用蘑菇提取物和麦角硫杆菌素作为活性成分。 解决方案：提供了Paneth细胞中抗微生物物质的生产和/或分泌促进剂，该促进剂使用从蘑菇中提取的来自蘑菇和/或作为活性成分的麦角硫杆菌素的提取物。 抗菌物质的生产和/或分泌促进剂使用食用菌提取物和麦角硫杆菌素作为活性成分，具有较高的安全性。 此外，抗微生物物质的生成和分泌促进剂促进生物体中Paneth细胞中的抗微生物物质的产生和分泌，从而可以活化生物体内的免疫，还可以预防和治疗疾病。 版权所有（C）2012，JPO＆INPIT

    Agent for improving swallowing difficulty (disphagia)
    85.
    发明专利
    Agent for improving swallowing difficulty (disphagia) 有权
    改善困难（DISPHAGIA）的代理

    公开(公告)号：JP2012158537A

    公开(公告)日：2012-08-23

    申请号：JP2011018030

    申请日：2011-01-31

    申请人： Noda Shokukin Kogyo Kk ,  野田食菌工業株式会社

    发明人： HIBINO YASUHIDE ,  IIZUKA HIROSHI ,  OKAZAKI MARI ,  MATSUZAKI HIROKAZU

    IPC分类号： A61K36/07 ,  A23L1/30 ,  A61P1/00

    摘要： PROBLEM TO BE SOLVED: To provide an agent for improving swallowing difficulty, without having side effects and capable of being lightly taken on a daily basis.SOLUTION: By using a medium containing a plant fibrous raw material, the mycelia of basidiomycete is cultured, and an extract material obtained by extracting the cultured material and containing sugars, proteins and water soluble lignin is used as an active ingredient of the agent for improving the swallowing difficulty. As the plant fibrous raw material, a material prepared from the plants of Graminaceae is preferable, and the material prepared from 1 kind or ≥2 kinds selected from bagasse, the stems and leaves of maize, wheat bran, rice bran, rice straws, cogongrasses, striped bamboo and bamboo is more preferable. As the basidiomycete, Ganogerma lucidum, Pachyma hoelen, Elfvingia applanata, Coriolus versicolor, Lentinula edodes, Ilisha elongata, Grifola fondosa, Flammulina velutipes, Lyophylum simeji, Hericium erinaceum, Agaricus blazei, etc., can be used.

    摘要翻译： 要解决的问题：提供一种用于改善吞咽困难的药剂，而不产生副作用并且能够每天轻度服用。 解决方案：通过使用含有植物纤维原料的培养基培养担子菌的菌丝体，通过提取培养物质并含有糖，蛋白质和水溶性木质素的提取物作为活性成分 用于改善吞咽困难的药剂。 作为植物性纤维原料，优选从禾本科植物制备的材料，从1种或2种选自甘蔗渣，玉米，麦麸，米糠，稻秆，gon草的茎和叶中选择的材料 条纹竹竹比较好。 作为担子菌，可以使用Ganogerma lucidum，Pachyma hoelen，Elfvingia applanata，Coriolus versicolor，Lentinula edodes，Ilisha elongata，Grifola fondosa，Flammulina velutipes，Lyophylum simeji，Hericium erinaceum，Agaricus blazei等。 版权所有（C）2012，JPO＆INPIT

    Antithrombotic agent
    86.
    发明专利
    Antithrombotic agent 审中-公开
    抗生素代谢物

    公开(公告)号：JP2012131754A

    公开(公告)日：2012-07-12

    申请号：JP2010286988

    申请日：2010-12-24

    申请人： Nippon Menaade Keshohin Kk ,  日本メナード化粧品株式会社

    发明人： MATSUMURA KIYOSHI ,  YAMADA SHIGEYUKI ,  SUZAKI SHINICHI

    IPC分类号： A61K36/18 ,  A23L1/30 ,  A61K36/07 ,  A61K36/28 ,  A61K36/42 ,  A61P1/08 ,  A61P7/02 ,  A61P9/10 ,  A61P9/12 ,  A61P17/00 ,  A61P25/28 ,  A61P29/00 ,  A61P43/00

    摘要： PROBLEM TO BE SOLVED: To provide a natural extract having antithrombotic effect, and a medicine, quasi drug or food containing the same, which can prevent and improve thrombosis or reduction in blood circulation due to a thrombus.SOLUTION: Extracts of marigold, passion vine, eyebright and balsam apple have excellent antithrombotic effects. A Ganoderma extract is used in combination therewith, whereby a synergistic effect is obtained. The food, quasi drug or medicine containing such an extract has antithrombotic effect, and is effective not only for improvement of thrombosis but also for prevention and improvement of symptomatic states involving thrombus such as arteriosclerosis, dullness of skin, dementia, shoulder stiffness, and headache.

    摘要翻译： 待解决的问题：提供具有抗血栓形成作用的天然提取物，以及含有该天然提取物的药物，准药物或食品，其能够预防和改善由于血栓引起的血液循环的血栓形成或血液循环的减少。 解决方案：万寿菊，激情藤，眼睛和苦瓜苹果提取物具有极好的抗血栓作用。 与其组合使用灵芝提取物，由此获得协同效应。 含有这种提取物的食品，准药物或药物具有抗血栓形成作用，不仅有利于改善血栓形成，而且对于预防和改善涉及血栓的症状状态如动脉硬化，皮肤晦暗，肩部僵硬和头痛也是有效的 。 版权所有（C）2012，JPO＆INPIT

    Melanin production promoter and neutral fat accumulation inhibitor
    89.
    发明专利
    Melanin production promoter and neutral fat accumulation inhibitor 有权
    空值

    公开(公告)号：JP4921754B2

    公开(公告)日：2012-04-25

    申请号：JP2005270627

    申请日：2005-09-16

    申请人： 株式会社ノエビア

    发明人： 由美子 奥村 ,  耕一郎 田村

    IPC分类号： A61K36/07 ,  A61K8/97 ,  A61P3/04 ,  A61P3/06 ,  A61P17/00 ,  A61Q5/00

    摘要： PROBLEM TO BE SOLVED: To find an active ingredient having an excellent melamine production-promoting action, an excellent neutral fat accumulation-inhibiting action, and the like to provide a melamine production promoter and a neutral fat accumulation inhibitor capable of being widely applied to the fields of compositions for hair, functional foods and the like. SOLUTION: This melamine production promoter and the neutral fat accumulation inhibitor contain each an extract of Antrodiacamphorata. The extract of the Antrodiacamphorata is compounded with a composition for hair or a composition such as a functional food to obtain various compositions exhibiting an excellent melamine production-promoting action and an excellent neutral fat accumulation-inhibiting action. COPYRIGHT: (C)2007,JPO&INPIT

    摘要翻译： 解决问题：为了找到具有优异的三聚氰胺生产促进作用的活性成分，优异的中性脂肪蓄积抑制作用等，以提供能够广泛应用的三聚氰胺生产促进剂和中性脂肪蓄积抑制剂 适用于头发，功能性食品等的组合物领域。 解决方案：这种三聚氰胺生产促进剂和中性脂肪蓄积抑制剂含有各自的抗di an提取物。 将抗di The提取物与头发组合物或功能性食品等组合物混合，得到具有优异的三聚氰胺生产促进作用和优异的中性脂肪蓄积抑制作用的各种组合物。 版权所有（C）2007，JPO＆INPIT