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    Cyclohex-2-enone compound from antrodia camphorata used for protecting liver
    2.
    发明专利
    Cyclohex-2-enone compound from antrodia camphorata used for protecting liver 审中-公开
    来自用于保护肝脏的ANTRODIA CAMPHORATA的CYCLOHEX-2-ENONE化合物

    公开(公告)号：JP2008308479A

    公开(公告)日：2008-12-25

    申请号：JP2007240271

    申请日：2007-09-14

    申请人： Golden Biotechnology Corp ,  國鼎生物科技股▲ふん▼有限公司

    发明人： LIU SHENG-YUNG ,  WEN WU-CHE ,  KUO MAO-TIEN

    IPC分类号： A61K36/07 ,  A61K31/122 ,  A61P1/16

    CPC分类号： A61K36/07 ,  A61K31/12 ,  C07C403/02 ,  C07C2601/16

    摘要： PROBLEM TO BE SOLVED: To provide a cyclohex-2-enone compound used for protecting liver.
    SOLUTION: The compound, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-2-cyclohex-2-enone, mainly isolated from an extract of Antrodia camphorata, is effective for protecting liver tissue. The cyclohex-2-enone compound from Antrodia camphorata alleviates/reduces levels of liver tissue injury and fibrosis induced by chemical liver injury, reduces the concentration of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), increases the contents of glutathione peroxidase (GSHPx) and catalase (CAT) in liver, reduces the liver damage caused by free radicals, thus increases antioxidant ability of the liver tissue and achieves function and effect of liver protection.
    COPYRIGHT: (C)2009,JPO&INPIT

    摘要翻译： 待解决的问题：提供用于保护肝脏的环己-2-烯酮化合物。 解决方案：4-羟基-2,3-二甲氧基-6-甲基-5（3,7,11-三甲基 - 十二-2,6,10-三烯基）-2-环己-2-烯酮化合物 主要从樟芝提取物中分离，对保护肝组织有效。 来自樟芝的环己-2-烯酮化合物缓解/降低化学性肝损伤引起的肝组织损伤和纤维化水平，降低丙氨酸氨基转移酶（ALT）和天冬氨酸氨基转移酶（AST）的浓度，增加谷胱甘肽过氧化物酶（GSHPx ）和过氧化氢酶（CAT），降低肝脏自由基的损伤，提高肝组织的抗氧化能力，达到肝脏保护的功能和作用。 版权所有（C）2009，JPO＆INPIT

    Cyclohexanone extract of antrodia camphorata
    3.
    发明专利
    Cyclohexanone extract of antrodia camphorata 有权
    环孢素提取物

    公开(公告)号：JP2008169194A

    公开(公告)日：2008-07-24

    申请号：JP2007126866

    申请日：2007-05-11

    申请人： Golden Biotechnology Corp ,  國鼎生物科技股▲ふん▼有限公司

    发明人： LIU SHENG-YUNG ,  WEN WU-CHE ,  TSOU WAN-LING ,  KUO MAO-TIEN ,  CHANG CHUNG-CHOU ,  HUANG CHUN-HUNG ,  LI YA-YING ,  FOK KA-HANG

    IPC分类号： A61K31/122 ,  A61K36/07 ,  A61P35/00 ,  A61P39/06 ,  C07C49/753

    CPC分类号： C07C403/02 ,  A61K36/07 ,  A61K36/074 ,  A61K38/00 ,  C07C2601/16 ,  A61K2300/00

    摘要： PROBLEM TO BE SOLVED: To provide a cyclohexanone extratct of Antrodia camphorata. SOLUTION: The invention relates to a new compound and its uses, which has been separated from an extract from Antrodia camphorata, in particular to 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, and its use in tumor growth inhibition. The compound of the invention, can be applied in inhibiting the growth of cancer cells, such as breast cancer, hepatic cancer and prostate cancer, and be used as a pharmaceutical composition to inhibit the tumor growth, or further be applied in prevention of heart and blood vessel disease or dietary supplements for health needs through its antioxidant activity. COPYRIGHT: (C)2008,JPO&INPIT

    摘要翻译： 要解决的问题：提供樟脑的环己酮外消旋。 解决方案：本发明涉及一种与樟脑油提取物分离的新化合物及其用途，特别涉及4-羟基-2,3-二甲氧基-6-甲基-5（3,7， 11-三甲基 - 十二烷-2,6,10-三烯基） - 环己-2-烯酮，以及其在肿瘤生长抑制中的用途。 本发明的化合物可用于抑制癌细胞如乳腺癌，肝癌和前列腺癌的生长，并可用作抑制肿瘤生长的药物组合物，或进一步用于预防心脏和 血管疾病或通过其抗氧化活性的健康需要的膳食补充剂。 版权所有（C）2008，JPO＆INPIT

    Composition for inhibiting growth of prostate cancer cell and method for formulation the same
    5.
    发明专利
    Composition for inhibiting growth of prostate cancer cell and method for formulation the same 审中-公开
    用于抑制前列腺癌细胞生长的组合物及其制备方法

    公开(公告)号：JP2006176508A

    公开(公告)日：2006-07-06

    申请号：JP2005359659

    申请日：2005-12-13

    申请人： Golden Biotechnology Corp ,  國鼎生物科技股▲ふん▼有限公司

    发明人： WANG YU-LUNG ,  LIU SHENG-YUNG ,  HUANG SAN-BAO

    IPC分类号： A61K36/00 ,  A61K31/337 ,  A61K31/352 ,  A61K36/48 ,  A61K45/00 ,  A61P13/08 ,  A61P35/00 ,  A61P37/02

    CPC分类号： A61K36/48 ,  A61K36/482

    摘要： PROBLEM TO BE SOLVED: To provide a composition effectively inhibiting the growth of prostate cancer cells and inhibiting the swelling of the prostate and to provide a method for formulating the same. SOLUTION: The composition for inhibiting the growth of the prostate cancer cells is characterized as a composition having an extract from Astragali Radix which is Radix et tuber of the family Leguminosae. The composition has active ingredients of the Astragali Radix or the extract from the Astragali Radix and effectively inhibits the growth of the prostate cancer cells and the swelling of the prostate. The method for formulating the composition is provided. COPYRIGHT: (C)2006,JPO&NCIPI

    摘要翻译： 要解决的问题：提供有效抑制前列腺癌细胞生长并抑制前列腺肿胀的组合物，并提供其配制方法。 解决方案：用于抑制前列腺癌细胞生长的组合物的特征在于具有黄芪提取物的组合物，其为豆科植物的根瘤菌。 该组合物具有黄芪的活性成分或黄芪提取物的有效成分，并有效抑制前列腺癌细胞的生长和前列腺的肿胀。 提供了配制方法。 版权所有（C）2006，JPO＆NCIPI

    New compound separated from antrodia camphorata extract
    9.
    发明专利
    New compound separated from antrodia camphorata extract 有权
    从ANTRODIA CAMPHORATA提取物分离的新化合物

    公开(公告)号：JP2009102286A

    公开(公告)日：2009-05-14

    申请号：JP2007294479

    申请日：2007-11-13

    申请人： Golden Biotechnology Corp ,  國鼎生物科技股▲ふん▼有限公司

    发明人： KUO MAO-TIEN ,  WEN WU-CHE ,  LIU SHENG-YUNG

    IPC分类号： C07C49/753 ,  A61K31/122 ,  A61K36/07 ,  A61P35/00 ,  C07C45/80

    CPC分类号： C07C403/10 ,  C07C403/08 ,  C07C2601/16

    摘要： PROBLEM TO BE SOLVED: To provide a new compound separated and purified from an extract of Antrodia camphorata and applicable for suppressing the growth of tumor cells. SOLUTION: The new compound and its use, in particular Antroquinonol B and Antroquinonol C isolated from Antrodia camphorata extracts, can effectively inhibit the growth of tumor cells. The compounds are first discovered from Antrodia camphorate and applicable not only in inhibiting growth of tumor cells of breast cancer, lung cancer, hepatic cancer and prostate cancer, but also as a component of medicinal compositions for suppressing the growth of the tumor cells. COPYRIGHT: (C)2009,JPO&INPIT

    摘要翻译： 待解决的问题：提供从樟芝提取物中分离和纯化的新化合物，适用于抑制肿瘤细胞的生长。 解决方案：新化合物及其用途，特别是Antroquinonol B和Antroquinonol C分离自樟脑提取物，可有效抑制肿瘤细胞的生长。 这些化合物首先从樟脑酸樟脑中发现，不仅可以抑制乳腺癌，肺癌，肝癌和前列腺癌的肿瘤细胞的生长，还可用作抑制肿瘤细胞生长的药物组合物的组分。 版权所有（C）2009，JPO＆INPIT

    Antrodia camphorata cyclohexane ketone compound used for relaxing physiological fatigue
    10.
    发明专利
    Antrodia camphorata cyclohexane ketone compound used for relaxing physiological fatigue 有权
    用于放松生理疲劳的ANTRODIA CAMPHORATA CYCLOHEXANE KETONE化合物

    公开(公告)号：JP2009023917A

    公开(公告)日：2009-02-05

    申请号：JP2007185653

    申请日：2007-07-17

    申请人： Golden Biotechnology Corp ,  國鼎生物科技股▲ふん▼有限公司

    发明人： LIU SHENG-YUNG ,  WEN WU-CHE ,  KUO MAO-TIEN

    IPC分类号： A61K31/122 ,  A61K36/06 ,  A61P3/02

    摘要： PROBLEM TO BE SOLVED: To provide an Antrodia camphorate cyclohexane ketone compound used for relaxing physiological fatigue. SOLUTION: 4-Hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone separated from an Antrodia camphorate extract can effectively relax physiological fatigue. After the high intense consumption motion of 80% maximum oxygen intake, the compound is immediately supplied to promote the metabolisms of body creatine kinase phosphate and blood ammonia, thereby achieving effects for helping the recovery of the concentration and for relaxing the physiological fatigues. COPYRIGHT: (C)2009,JPO&INPIT

    摘要翻译： 要解决的问题：提供用于缓解生理疲劳的用于樟脑酸的环己烷酮化合物。 解决方案：从Antrodia camphorate分离的4-羟基-2,3-二甲氧基-6-甲基-5（3,7,11-三甲基 - 十二-2,6,10-三烯基） - 环己-2-烯酮 提取物可有效缓解生理疲劳。 在80％最大氧摄入量的高度剧烈消耗运动之后，立即供应化合物以促进身体肌酸激酶磷酸盐和血氨的代谢，从而达到帮助恢复浓度和放松生理疲劳的效果。 版权所有（C）2009，JPO＆INPIT