公开(公告)号：JP2008150306A

公开(公告)日：2008-07-03

申请号：JP2006338533

申请日：2006-12-15

Applicant: Air Water Inc ,  エア・ウォーター株式会社

Inventor： KANAI MAKOTO ,  UMETSU JUNICHI ,  TSUCHIDA YASUHIRO

IPC: A61K47/42 ,  A61K9/10 ,  A61K9/14 ,  A61K9/20 ,  A61K9/70

Abstract: PROBLEM TO BE SOLVED: To provide a gelatin molded product comprising a base in a state with little deterioration and capable of sustainedly releasing the base over a long period of time and to provide a method for producing the molded product.
SOLUTION: The gelatin molded product comprises gelatin and the base dispersed in the gelatin which is cross-linked only in a surface layer of the molded product. The method for producing the gelatin molded product comprises a mixture fluid preparing step of preparing the mixture fluid containing the base and the gelatin, a molding step of molding the mixture fluid, a gelation step of cooling the gelatin in the mixture fluid, making the gelatin gel and thereby preparing a mixture gel and a cross-linking step of adding a cross-linking agent to the mixture gel, advancing a cross-linking reaction of the mixture gel kept in a gelled state and thereby cross-linking the gelatin only in the surface layer of the mixture gel. As a result, the gelatin molded product in which the gelatin is cross-linked only in the surface layer is produced by the steps.
COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供一种明胶模制品，其包含几乎没有劣化状态的碱，并且能够长时间地持续释放碱，并提供一种生产该模塑产品的方法。 解决方案：明胶模制产品包括明胶和分散在明胶中的基质，其仅在成型产品的表面层中交联。 制造明胶成型体的方法包括制备含有碱和明胶的混合液的混合液制备步骤，模制混合液的成型步骤，将混合液中明胶冷却的凝胶化步骤，使明胶 凝胶，从而制备混合物凝胶和将交联剂加入到混合物凝胶中的交联步骤，使混合凝胶的交联反应保持凝胶状态，从而仅在 混合物凝胶表面层。 结果，仅通过表面层交联明胶的明胶模制品通过这些步骤产生。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2012197246A

公开(公告)日：2012-10-18

申请号：JP2011062326

申请日：2011-03-22

Applicant: Air Water Inc ,  エア・ウォーター株式会社

Inventor： KANAI MAKOTO ,  UMETSU JUNICHI ,  OKUMURA NAOKI

IPC: C07K14/78 ,  C07K1/24 ,  C12M1/42

Abstract: PROBLEM TO BE SOLVED: To provide a novel method for causing a protein to be of low molecular weight, which can solve the problem arising in conventional methods using proteases.SOLUTION: This invention relates to the method of causing the protein to be of low-molecular weight through a plasma treatment. The plasma treatment is preferably an atmospheric plasma treatment. The plasma treatment is preferably carried out by placing a protein between parallel flat plate electrodes. The protein is preferably a solid.

Abstract translation: 要解决的问题：提供使蛋白质具有低分子量的新方法，其可以解决使用蛋白酶的常规方法中产生的问题。 解决方案：本发明涉及通过等离子体处理使蛋白质成为低分子量的方法。 等离子体处理优选为大气等离子体处理。 等离子体处理优选通过将蛋白质放置在平行平板电极之间进行。 蛋白质优选为固体。 版权所有（C）2013，JPO＆INPIT

公开(公告)号：JP2009242773A

公开(公告)日：2009-10-22

申请号：JP2008288305

申请日：2008-11-11

Applicant: Air Water Inc ,  エア・ウォーター株式会社

Inventor： TSUCHIDA YASUHIRO ,  OOKA YASUNORI ,  KANAI MAKOTO

IPC: C10L3/06 ,  B01D53/22 ,  C10L3/10

CPC classification number: Y02C10/10

Abstract: PROBLEM TO BE SOLVED: To provide a methane gas concentration device which can obtain a methane gas with a high concentration at a high recovery rate. SOLUTION: The methane gas concentration device 1 where, from a mixed gas at least comprising a methane gas and carbon dioxide, the carbon dioxide is separated, so as to concentrate the methane gas, includes: a first concentration apparatus 11 where the methane gas is concentrated by a separation membrane allowing the carbon dioxide to preferentially permeate from the mixed gas; a second concentration apparatus 12 where the methane gas is further concentrated by a separation membrane allowing the carbon dioxide to preferentially permeate from a non-permeating gas in the first concentration apparatus 11; and a recovery apparatus 13 where the methane gas is recovered by a separation membrane allowing the carbon dioxide to further preferentially permeate from a permeating gas in the first concentration apparatus 11, thus, the methane gas with a high concentration can be obtained at a high recovery rate. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 解决的问题：提供能够以高回收率获得浓度高的甲烷气体的甲烷气体浓缩装置。 解决方案：甲烷气体浓缩装置1，其中，从至少包含甲烷气体和二氧化碳的二氧化碳的二氧化碳的混合气体中分离出二氧化碳以浓缩甲烷气体，其包括：第一浓缩装置11，其中 甲烷气体被分离膜浓缩，使得二氧化碳优先从混合气体渗透; 第二浓缩装置12，其中甲烷气体通过分离膜进一步浓缩，允许二氧化碳优先从第一浓缩装置11中的非渗透气体渗透; 以及回收装置13，其中通过分离膜回收甲烷气体，使得二氧化碳进一步优先地从第一浓缩装置11中的渗透气体渗透，从而可以以高回收率获得浓度高的甲烷气体 率。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2006167164A

公开(公告)日：2006-06-29

申请号：JP2004363937

申请日：2004-12-16

Applicant: Air Water Inc ,  エア・ウォーター株式会社

Inventor： TSUCHIDA YASUHIRO ,  KANAI MAKOTO ,  MIYAZAKI SATOSHI ,  UMETSU JUNICHI

IPC: A61L15/00 ,  A61K8/02 ,  A61K9/70

Abstract: PROBLEM TO BE SOLVED: To provide a method for efficiently manufacturing many collagen sheets collectively without damaging smoothness and flatness of a sheet surface.
SOLUTION: After forming a collagen solution frozen layer 11 by pouring a collagen solution into a tray 10 and freezing it, a water frozen layer 12 is formed by pouring water on the collagen solution frozen layer and freezing it and then, a collagen solution frozen layer 11 is formed by pouring the collagen solution on the water frozen layer 12 to be frozen. A block 13 is formed by alternately repeating the process of forming the water frozen layer 12 and the process of forming the collagen solution frozen layer. By vacuum-drying the block 13, moisture contained in the respective collagen solution frozen layer 11 is sublimated and removed and they are changed into porous collagen sheets respectively. Additionally, the water frozen layer 12 is sublimated and removed, and the respective collagen sheets are obtained in the state of being directly laminated.
COPYRIGHT: (C)2006,JPO&NCIPI

Abstract translation: 要解决的问题：提供一种在不损害片材表面的平滑度的同时有效地制造许多胶原片的方法。 解决方案：通过将胶原蛋白溶液倒入托盘10并冷冻来形成胶原蛋白溶液冷冻层11后，通过将水倒入胶冻溶液冷冻层并冷冻而形成水冻层12，然后将胶原蛋白 通过将胶原溶液倾倒在待冻结的水冻结层12上形成溶液冷冻层11。 通过交替重复形成水冻结层12的工序和形成胶原蛋白冻结层的工序来形成块13。 通过对块13进行真空干燥，将各胶原溶液冷冻层11中含有的水分升华除去，分别变为多孔性胶原片。 此外，将水冻层12升华除去，并且以直接层压的状态获得各胶原片。 版权所有（C）2006，JPO＆NCIPI

公开(公告)号：JP2012206999A

公开(公告)日：2012-10-25

申请号：JP2011075265

申请日：2011-03-30

Applicant: Air Water Inc ,  エア・ウォーター株式会社

Inventor： KANAI MAKOTO ,  UMETSU JUNICHI

IPC: A61K38/17 ,  A61K8/65

CPC classification number: Y02P20/544

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing odorless collagen from which an odor component is extracted and removed without damaging the triple helix structure of collagen, and the odorless collagen obtained thereby.SOLUTION: Dried collagen 3 is immersed into carbon dioxide in a liquid state or in a supercritical state, which does not contain an organic solvent, at the inside of a cleaning tank 1 whose inside temperature lies in the range of 0 to 40°C for 5 to 60 min, and an odor component included in the dried collagen 3 is extracted and removed.

Abstract translation: 待解决的问题：提供一种生产无臭胶原蛋白的方法，从而从其中提取和除去气味组分而不损害胶原的三螺旋结构，并且由此获得无味的胶原。 解决方案：在内部温度在0至40℃的清洗槽1的内部，将干胶原3浸入液态或超临界状态的二氧化碳（不含有机溶剂） ℃5〜60分钟，提取除去干燥的胶原3中含有的气味成分。 版权所有（C）2013，JPO＆INPIT

公开(公告)号：JP2010132770A

公开(公告)日：2010-06-17

申请号：JP2008309865

申请日：2008-12-04

Applicant: Air Water Inc ,  Idemitsu Technofine Co Ltd ,  エア・ウォーター株式会社 ,  出光テクノファイン株式会社

Inventor： TAJIMA TAKEJI ,  UMETSU JUNICHI ,  KANAI MAKOTO

IPC: C09J189/00 ,  A61L24/00 ,  C09J11/06

Abstract: PROBLEM TO BE SOLVED: To provide an adhesive having low toxicity and excellent convenience. SOLUTION: The adhesive includes a base compound and a crosslinker. The base compound includes, as a main ingredient, gelatin which is soluble in water at ambient temperature and has a denatured collagen with a thermal denaturation temperature of ≤25°C. Since this adhesive employs a base compound containing a specific gelatin as a main ingredient, it enables rapid mixing and reaction of the base compound and the crosslinker without requiring preheating, and can be economically and stably produced. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供具有低毒性和极好方便性的粘合剂。 粘合剂包括基础化合物和交联剂。 碱性化合物作为主要成分包括在环境温度下可溶于水的明胶，并具有热变性温度为≤25℃的变性胶原。 由于该粘合剂采用含有特定明胶作为主要成分的碱性化合物，因此能够在不需要预热的情况下快速地混合和反应基础化合物和交联剂，并且可以经济地和稳定地生产。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2007211170A

公开(公告)日：2007-08-23

申请号：JP2006033874

申请日：2006-02-10

Applicant: Air Water Inc ,  エア・ウォーター株式会社

Inventor： TSUCHIDA YASUHIRO ,  KANAI MAKOTO ,  UMETSU JUNICHI ,  TOMIYAMA EMIKO

IPC: C09H3/00

Abstract: PROBLEM TO BE SOLVED: To provide a production method for obtaining endotoxin-reduced gelatin having an endotoxin content reduced to an amount capable of being used in bodies without largely changing the molecular structure of the gelatin.
SOLUTION: This method for producing endotoxin-reduced gelatin obtained from collagen originated from fishes or shellfishes comprises a gelatin-producing process for thermally changing collagen into gelatin, and an endotoxin-inactivating process for heating the gelatin in an environment in a pH range of 5.0 to 9.0 to inactivate the endotoxin in the gelatin, thus obtaining the endotoxin-reduced gelatin.
COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 待解决的问题：提供一种制备内毒素还原明胶的制备方法，该明胶的内毒素含量降低至能够在体内使用的量，而不会明显改变明胶的分子结构。 解决方案：用于生产由鱼类或贝类产生的胶原产生的内毒素还原明胶的方法包括用于将胶原蛋白热变换成明胶的明胶生产方法和用于在pH环境中加热明胶的内毒素灭活方法 范围为5.0〜9.0，使明胶中的内毒素失活，得到内毒素还原明胶。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP2004269478A

公开(公告)日：2004-09-30

申请号：JP2003066318

申请日：2003-03-12

Applicant: Air Water Inc ,  エア・ウォーター株式会社

Inventor： MIYAZAKI SATOSHI ,  KANAI MAKOTO

IPC: A23J1/04 ,  A23J3/04 ,  A61L27/00 ,  C07K1/14 ,  C07K14/78

Abstract: PROBLEM TO BE SOLVED: To provide a collagen production method by which collagen can efficiently be mass-produced from the skin of fishes. SOLUTION: This method for producing collagen comprises the processes of: insolubilizing the epidermal layer of the fishes skin and a cutis layer portion of the epidermal layer side including pigmentary cells; swelling at least a part of the cutis layer which is not insolubilized; and recovering the swollen cutis layer. In the method, it is possible to include a filtering process and also a centrifuging process. COPYRIGHT: (C)2004,JPO&NCIPI

公开(公告)号：JP2010100535A

公开(公告)日：2010-05-06

申请号：JP2008271049

申请日：2008-10-21

Applicant: Air Water Inc ,  エア・ウォーター株式会社

Inventor： UMETSU JUNICHI ,  TOMIYAMA EMIKO ,  KANAI MAKOTO

IPC: A61K8/65 ,  A61K8/02 ,  A61Q19/00

Abstract: PROBLEM TO BE SOLVED: To provide a method for manufacturing a collagen sheet controlling a transferring amount of collagen to external matter such as the skin.
SOLUTION: The method for manufacturing the collagen sheet comprises: a step of spraying a collagen dispersion to a substrate; a step of freeze-drying the substrate onto which the collagen dispersion is sprayed; and a step of heating the freeze-dried substrate under reduced pressure. Preferably, the substrate is a nonwoven fabric.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供一种制造胶原片的方法，所述胶原片控制胶原蛋白的转移量到皮肤等外部物质。 解决方案：用于制造胶原片的方法包括：将胶原分散体喷涂到基材上的步骤; 将其上喷涂有胶原分散体的基材冷冻干燥的步骤; 以及在减压下加热冷冻干燥的基材的工序。 优选地，基材是无纺布。 版权所有（C）2010，JPO＆INPIT