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公开(公告)号:JP2014012650A
公开(公告)日:2014-01-23
申请号:JP2012151120
申请日:2012-07-05
申请人: Nihon Univ , 学校法人日本大学
发明人: GON YASUHIRO , HASHIMOTO OSAMU
IPC分类号: A61K31/7125 , A61P17/00 , A61P43/00 , C12N15/117
摘要: PROBLEM TO BE SOLVED: To provide a method and an agent for enhancing epithelium barrier function.SOLUTION: The method for enhancing epithelium barrier function comprises the step of bringing oligonucleotide containing a non-methylated CpG sequence into contact with an epithelium cell. The agent for enhancing epithelium barrier function contains the oligonucleotide containing the non-methylated CpG sequence.
摘要翻译: 要解决的问题:提供增强上皮屏障功能的方法和试剂。解决方案:增强上皮屏障功能的方法包括使含有非甲基化CpG序列的寡核苷酸与上皮细胞接触的步骤。 用于增强上皮屏障功能的药物含有含有非甲基化CpG序列的寡核苷酸。