公开(公告)号：JP2005154329A

公开(公告)日：2005-06-16

申请号：JP2003393929

申请日：2003-11-25

Applicant: Sds Biotech Corp ,  株式会社エス・ディー・エス バイオテック

Inventor： TABUCHI TOSHIHIKO ,  KOMATSUBARA KENICHI

IPC: C07C45/75 ,  C07C49/653

Abstract: PROBLEM TO BE SOLVED: To provide a method for efficiently producing methylene norcamphor under mild conditions.
SOLUTION: The method for producing methylene norcamphor comprises (A) carrying out a reaction between formaldehyde and norcamphor under heating at ≥60°C in the presence of a secondary amine and an organic acid, or (B) carrying out a reaction between an aqueous formaldehyde solution( formalin ) and norcamphor under heating at ≥60°C in the presence of a secondary amine and an organic acid. In this method, (1) prior to or during the reaction under heating, an extraction solvent for the methylene norcamphor is added, or (2) after the reaction under heating, the extraction solvent for the methylene norcamphor is added followed by heating to ≥60°C.
COPYRIGHT: (C)2005,JPO&NCIPI

Abstract translation: 待解决的问题：提供一种在温和条件下有效生产亚甲基樟脑的方法。 （A）在仲胺和有机酸的存在下，在≥60℃加热下进行甲醛与降樟脑的反应，或者（B）进行反应 在甲醛水溶液（福尔马林）和正樟脑之间，在仲胺和有机酸的存在下，在≥60℃加热。 在该方法中，（1）在加热反应之前或期间，加入亚甲基樟脑的萃取溶剂，或（2）加热反应后，加入亚甲基樟脑的萃取溶剂，加热至≥ 60℃。 版权所有（C）2005，JPO＆NCIPI