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公开(公告)号:US20120329094A1
公开(公告)日:2012-12-27
申请号:US13559464
申请日:2012-07-26
申请人: Allen J. Ebens, JR. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
发明人: Allen J. Ebens, JR. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
CPC分类号: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
摘要: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
摘要翻译: 提供抗CD22抗体及其免疫偶联物。 提供了使用抗CD22抗体及其免疫偶联物的方法。
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公开(公告)号:US5169762A
公开(公告)日:1992-12-08
申请号:US242093
申请日:1988-09-08
申请人: Alane M. Gray , Axel Ullrich
发明人: Alane M. Gray , Axel Ullrich
摘要: The .beta.-subunit of human nerve growth factor (.beta.NGF) is prepared in essentially pure form in commercially viable quantities using recombinant DNA technology. The nucleotide sequence and vectors encoding human .beta.NGF and host cells transformed with the vectors are also provided.
摘要翻译: 人神经生长因子(βNGF)的β亚单位以基本上纯的形式以商业上可行的量使用重组DNA技术制备。 还提供了编码人βNGF的核苷酸序列和载体以及用载体转化的宿主细胞。
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公开(公告)号:US20130171170A1
公开(公告)日:2013-07-04
申请号:US13494845
申请日:2012-06-12
申请人: ALLEN J. EBENS, JR. , ALANE M. GRAY , WEI-CHING LIANG , YAN WU , SHANG-FAN YU
发明人: ALLEN J. EBENS, JR. , ALANE M. GRAY , WEI-CHING LIANG , YAN WU , SHANG-FAN YU
IPC分类号: C07K16/28
CPC分类号: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
摘要: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
摘要翻译: 提供抗CD22抗体及其免疫偶联物。 提供了使用抗CD22抗体及其免疫偶联物的方法。
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公开(公告)号:US08226945B2
公开(公告)日:2012-07-24
申请号:US12939533
申请日:2010-11-04
申请人: Allen J. Ebens, Jr. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
发明人: Allen J. Ebens, Jr. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
IPC分类号: A61K39/395 , A61K39/00 , C07K16/28 , C07K16/46 , C12P21/08
CPC分类号: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
摘要: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
摘要翻译: 提供抗CD22抗体及其免疫偶联物。 提供了使用抗CD22抗体及其免疫偶联物的方法。
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公开(公告)号:US20110142859A1
公开(公告)日:2011-06-16
申请号:US12939533
申请日:2010-11-04
申请人: ALLEN J. EBENS, JR. , ALANE M. GRAY , WEI-CHING LIANG , YAN WU , SHANG-FAN YU
发明人: ALLEN J. EBENS, JR. , ALANE M. GRAY , WEI-CHING LIANG , YAN WU , SHANG-FAN YU
IPC分类号: A61K39/395 , C07K16/28 , A61P35/00 , A61P35/02
CPC分类号: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
摘要: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
摘要翻译: 提供抗CD22抗体及其免疫偶联物。 提供了使用抗CD22抗体及其免疫偶联物的方法。
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公开(公告)号:US08394607B2
公开(公告)日:2013-03-12
申请号:US13559464
申请日:2012-07-26
申请人: Allen J. Ebens, Jr. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
发明人: Allen J. Ebens, Jr. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
CPC分类号: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
摘要: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
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公开(公告)号:US08557768B1
公开(公告)日:2013-10-15
申请号:US08417188
申请日:1995-04-04
申请人: Alane M. Gray , Axel Ullrich
发明人: Alane M. Gray , Axel Ullrich
摘要: The β-subunit of human nerve growth factor (βNGF) is prepared in essentially pure form in commercially useful quantities using recombinant DNA technology. The nucleotide sequence and vectors encoding human βNGF and host cells transformed with the vectors are also provided. The βNGF which the invention provides is useful, for example, in treating nerve damage.
摘要翻译: 人神经生长因子(βNGF)的β-亚基以基本上纯的形式以商业上有用的量使用重组DNA技术制备。 还提供了核苷酸序列和编码人βNGF的载体和用载体转化的宿主细胞。 本发明提供的βNGF可用于例如治疗神经损伤。
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公开(公告)号:US08524865B2
公开(公告)日:2013-09-03
申请号:US11754899
申请日:2007-05-29
申请人: Allen J. Ebens, Jr. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
发明人: Allen J. Ebens, Jr. , Alane M. Gray , Wei-Ching Liang , Yan Wu , Shang-Fan Yu
CPC分类号: C07K16/3061 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , C07K16/2803 , C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/77 , C07K2317/92
摘要: Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided.
摘要翻译: 提供抗CD22抗体及其免疫偶联物。 提供了使用抗CD22抗体及其免疫偶联物的方法。
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公开(公告)号:US5288622A
公开(公告)日:1994-02-22
申请号:US897221
申请日:1992-06-11
申请人: Alane M. Gray , Axel Ullrich
发明人: Alane M. Gray , Axel Ullrich
摘要: The .beta.-subunit of human nerve growth factor (.beta.NGF) is prepared in essentially pure form in commercially viable quantities using recombinant DNA technology. The nucleotide sequence and vectors encoding human .beta.NGF and host cells transformed with the vectors are also provided.
摘要翻译: 人神经生长因子(βNGF)的β亚单位以基本上纯的形式以商业上可行的量使用重组DNA技术制备。 还提供了编码人βNGF的核苷酸序列和载体以及用载体转化的宿主细胞。
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