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公开(公告)号:US5998400A
公开(公告)日:1999-12-07
申请号:US836405
申请日:1997-05-01
IPC分类号: A61K31/55 , A61K31/554 , A61P3/06 , A61P9/10 , C07D281/10 , C07D417/04 , C07F9/6536
CPC分类号: C07F9/6536 , C07D281/10
摘要: The invention is concerned with novel hypolipidemic compounds of formula (I), with processes and novel intermediates for their preparation, pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions, and associated diseases such as atherosclerosis. ##STR1##
摘要翻译: PCT No.PCT / GB95 / 02700 Sec。 371日期1997年5月1日 102(e)日期1997年5月1日PCT提交1995年11月16日PCT公布。 出版物WO96 / 16051 日期1996年5月30日本发明涉及式(I)的新型降血脂药物,其制备方法和新型中间体,含有它们的药物组合物及其在医药中的应用,特别是在预防和治疗高脂血症病症中以及相关的 疾病如动脉粥样硬化。
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公开(公告)号:US07189851B2
公开(公告)日:2007-03-13
申请号:US10507006
申请日:2003-02-24
申请人: Ashok Bhandari , Eric Eugene Boros , David John Cowan , Anthony Louis Handlon , Clifton Earl Hyman , Jeffrey Alan Oplinger , Michael Howard Rabinowitz , Philip Stewart Turnbull
发明人: Ashok Bhandari , Eric Eugene Boros , David John Cowan , Anthony Louis Handlon , Clifton Earl Hyman , Jeffrey Alan Oplinger , Michael Howard Rabinowitz , Philip Stewart Turnbull
IPC分类号: C07D471/00 , C07D491/00 , C07D498/00 , C07D513/00 , C07D515/00
CPC分类号: C07D471/14 , C07D487/04
摘要: The present invention relates to novel fused heterocyclic ring system compounds and methods for their use in the treatment and prevention of diseases or conditions.
摘要翻译: 本发明涉及新颖的稠合杂环体系化合物及其用于治疗和预防疾病或病症的方法。
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公开(公告)号:US06465451B1
公开(公告)日:2002-10-15
申请号:US09582907
申请日:2000-07-06
IPC分类号: A61K3155
CPC分类号: C07D281/10
摘要: The invention is concerned with novel hypolipidemic compounds of formula (I), wherein R1 is H or methyl, and salts, solvates or physiologically functional derivatives thereof, with processes and novel intermediates for their preparation, pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions and associated diseases, such as atherosclerosis.
摘要翻译: 本发明涉及式(I)的新型降血脂药物,其中R 1为H或甲基,以及其盐,溶剂合物或其生理功能衍生物,其制备方法和新中间体,含有它们的药物组合物及其在医药中的应用 ,特别是预防和治疗高脂血症和相关疾病如动脉粥样硬化。
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