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公开(公告)号：US08273744B2
公开(公告)日：2012-09-25
申请号：US12365671
申请日：2009-02-04
申请人： Neal C. Birnberg , Hong Liu , Qing Ping Weng , Haibo Shang , Pan Yin , Sharanappa B. Rajur , Hwa-Ok Kim , Paresh D. Salgaonkar , Norton P. Peet
发明人： Neal C. Birnberg , Hong Liu , Qing Ping Weng , Haibo Shang , Pan Yin , Sharanappa B. Rajur , Hwa-Ok Kim , Paresh D. Salgaonkar , Norton P. Peet
IPC分类号： A01N43/58 , A01N43/42 , A01N43/38 , A61K43/60 , A61K31/44 , A61K31/405 , C07D471/00 , C07D215/00 , C07D209/04
CPC分类号： C07D498/04 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D209/42 , C07D215/54 , C07D215/56 , C07D401/04 , C07D403/04 , C07D471/04
摘要： The present invention relates to compounds and pharmaceutically acceptable salts, esters and prodrugs of Formula (I) or (II): which are useful as AMPK modulators effective in treating diabetes, obesity and cancer in a subject.
摘要翻译： 本发明涉及式（I）或（II）的化合物和药学上可接受的盐，酯和前药：其可用作对受试者中有效治疗糖尿病，肥胖和癌症的AMPK调节剂。
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公开(公告)号：US20100009992A1
公开(公告)日：2010-01-14
申请号：US12365671
申请日：2009-02-04
申请人： Neal C. Birnberg , Hong Liu , Qing Ping Weng , Haibo Shang , Pan Yin , Sharanappa B. Rajur , Hwa-Ok Kim , Paresh D. Salgaonkar , Norton P. Peet
发明人： Neal C. Birnberg , Hong Liu , Qing Ping Weng , Haibo Shang , Pan Yin , Sharanappa B. Rajur , Hwa-Ok Kim , Paresh D. Salgaonkar , Norton P. Peet
IPC分类号： A61K31/437 , A61K31/4985 , A61K31/4375 , A61K31/47 , A61K31/404 , C07D498/04 , C07D471/04 , C07D215/20 , C07D209/12 , A61P35/00 , A61P3/10 , A61P3/04
CPC分类号： C07D498/04 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D209/42 , C07D215/54 , C07D215/56 , C07D401/04 , C07D403/04 , C07D471/04
摘要： The present invention relates to compounds and pharmaceutically acceptable salts, esters and prodrugs of Formula (I) or (II): which are useful as AMPK modulators effective in treating diabetes, obesity and cancer in a subject.
摘要翻译： 本发明涉及式（I）或（II）的化合物和药学上可接受的盐，酯和前药：其可用作对受试者中有效治疗糖尿病，肥胖和癌症的AMPK调节剂。
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公开(公告)号：US08980895B2
公开(公告)日：2015-03-17
申请号：US13571218
申请日：2012-08-09
申请人： Neal C. Birnberg , Hong Liu , Qing Ping Weng , Haibo Shang , Pan Yin , Sharanappa B. Rajur , Hwa-Ok Kim , Paresh D. Salgaonkar , Norton P. Peet
发明人： Neal C. Birnberg , Hong Liu , Qing Ping Weng , Haibo Shang , Pan Yin , Sharanappa B. Rajur , Hwa-Ok Kim , Paresh D. Salgaonkar , Norton P. Peet
IPC分类号： A01N43/58 , A01N43/42 , A01N43/38 , A61K31/44 , A61K31/405 , C07D471/00 , C07D215/00 , C07D209/04 , C07D209/08 , C07D209/14 , C07D209/42 , C07D215/54 , C07D401/04 , C07D403/04 , C07D471/04 , C07D498/04
CPC分类号： C07D498/04 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D209/42 , C07D215/54 , C07D215/56 , C07D401/04 , C07D403/04 , C07D471/04
摘要： The present invention relates to compounds and pharmaceutically acceptable salts, esters and prodrugs of Formula (I) or (II): which are useful as AMPK modulators effective in treating diabetes, obesity and cancer in a subject.
摘要翻译： 本发明涉及式（I）或（II）的化合物和药学上可接受的盐，酯和前药：其可用作对受试者中有效治疗糖尿病，肥胖和癌症的AMPK调节剂。
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公开(公告)号：US20120302576A1
公开(公告)日：2012-11-29
申请号：US13571218
申请日：2012-08-09
申请人： Neal C. Birnberg , Hong Liu , Qing Ping Weng , Haibo Shang , Pan Yin , Sharanappa B. Rajur , Hwa-Ok Kim , Paresh D. Salgaonkar , Norton P. Peet
发明人： Neal C. Birnberg , Hong Liu , Qing Ping Weng , Haibo Shang , Pan Yin , Sharanappa B. Rajur , Hwa-Ok Kim , Paresh D. Salgaonkar , Norton P. Peet
IPC分类号： A61K31/404 , C07D215/54 , A61K31/47 , C07D498/04 , A61K31/437 , C07D471/04 , A61K31/4375 , C07D209/42 , C07D403/10 , A61K31/501 , C07D401/10 , A61K31/4439 , A61P3/10 , A61P3/04 , A61P35/00 , A61K31/4985 , C07D209/08
CPC分类号： C07D498/04 , C07D209/08 , C07D209/12 , C07D209/14 , C07D209/18 , C07D209/42 , C07D215/54 , C07D215/56 , C07D401/04 , C07D403/04 , C07D471/04
摘要： The present invention relates to compounds and pharmaceutically acceptable salts, esters and prodrugs of Formula (I) or (II): which are useful as AMPK modulators effective in treating diabetes, obesity and cancer in a subject.
摘要翻译： 本发明涉及式（I）或（II）的化合物和药学上可接受的盐，酯和前药：其可用作对受试者中有效治疗糖尿病，肥胖和癌症的AMPK调节剂。
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