公开(公告)号：US07693664B2

公开(公告)日：2010-04-06

申请号：US11062833

申请日：2005-02-23

申请人： Hideto Takami ,  Koki Horikoshi ,  Yoshihiro Takaki ,  Gab-Joo Chee ,  Shinro Nishi ,  Shigeru Shimamura ,  Hiroko Suzuki ,  Ikuo Uchiyama ,  Zhijun Li

发明人： Hideto Takami ,  Koki Horikoshi ,  Yoshihiro Takaki ,  Gab-Joo Chee ,  Shinro Nishi ,  Shigeru Shimamura ,  Hiroko Suzuki ,  Ikuo Uchiyama ,  Zhijun Li

IPC分类号： G01N33/48

CPC分类号： G06F19/24

摘要： The invention relates to a method of judging the thermostability of a protein, comprising the steps of calculating an analytical value specific to a test protein by a principal component analysis based on the amino acid composition of the protein calculated from the data of the amino acid sequence of the protein or the nucleotide sequence of the gene and comparing the analytical value with an analytical value of a protein which is retained by a thermostable organism and corresponds to the test protein, and further relates to a program for allowing a computer to execute processing for judging the thermostability of a protein by the method, and a computer readable recording medium having recorded the program thereon.

摘要翻译： 本发明涉及一种判断蛋白质的热稳定性的方法，包括以下步骤：基于由氨基酸序列的数据计算的蛋白质的氨基酸组成，通过主成分分析计算测试蛋白质特异性的分析值 的蛋白质或该基因的核苷酸序列，并将分析值与由热稳定性生物体保留并对应于测试蛋白质的蛋白质的分析值进行比较，并且还涉及允许计算机执行处理的程序 通过该方法判断蛋白质的热稳定性，以及在其上记录有程序的计算机可读记录介质。

公开(公告)号：US20050202409A1

公开(公告)日：2005-09-15

申请号：US11062833

申请日：2005-02-23

申请人： Hideto Takami ,  Koki Horikoshi ,  Yoshihiro Takaki ,  Gab-Joo Chee ,  Shinro Nishi ,  Shigeru Shimamura ,  Hiroko Suzuki ,  Ikuo Uchiyama ,  Zhijun Li

发明人： Hideto Takami ,  Koki Horikoshi ,  Yoshihiro Takaki ,  Gab-Joo Chee ,  Shinro Nishi ,  Shigeru Shimamura ,  Hiroko Suzuki ,  Ikuo Uchiyama ,  Zhijun Li

IPC分类号： C12Q1/00 ,  G01N33/48 ,  G01N33/50 ,  G06F19/00

CPC分类号： G06F19/24

摘要： The invention relates to a method of judging the thermostability of a protein, comprising the steps of calculating an analytical value specific to a test protein by a principal component analysis based on the amino acid composition of the protein calculated from the data of the amino acid sequence of the protein or the nucleotide sequence of the gene and comparing the analytical value with an analytical value of a protein which is retained by a thermostable organism and corresponds to the test protein, and further relates to a program for allowing a computer to execute processing for judging the thermostability of a protein by the method, and a computer readable recording medium having recorded the program thereon.

摘要翻译： 本发明涉及一种判断蛋白质的热稳定性的方法，包括以下步骤：基于由氨基酸序列的数据计算的蛋白质的氨基酸组成，通过主成分分析计算测试蛋白质特异性的分析值 的蛋白质或该基因的核苷酸序列，并将分析值与由热稳定性生物体保留并对应于测试蛋白质的蛋白质的分析值进行比较，并且还涉及允许计算机执行处理的程序 通过该方法判断蛋白质的热稳定性，以及在其上记录有程序的计算机可读记录介质。