公开(公告)号：US09765084B2

公开(公告)日：2017-09-19

申请号：US12421245

申请日：2009-04-09

Applicant: Charles Guthrie Moyers ,  James Kermit Withrow ,  John Leonard Stephens

Inventor： Charles Guthrie Moyers ,  James Kermit Withrow ,  John Leonard Stephens

IPC: A61K31/495 ,  A61K31/7048 ,  A61K9/28 ,  A61K9/48 ,  C07D493/04 ,  C07H1/06

CPC classification number: C07D493/04 ,  C07H1/06

Abstract: A process for the production of a refined dianhydrosugar-containing product is disclosed. The process includes controlled continuous crystallization of the dianhydrosugar-containing product to produce a solution saturated with the dianhydrosugar. The saturated solution is mechanically separated, for example by centrifugation, and the crystalline product is washed. The only solvent used is water. The dianhydrosugar-containing product is upgraded to at least 99.8% purity and recovery is 95% or greater.Recrystallization of the dianhydrosugar of 99.8% purity results in an ultra pure product containing at least 99.99% dianhydrosugar.

公开(公告)号：US20090259056A1

公开(公告)日：2009-10-15

申请号：US12421245

申请日：2009-04-09

Applicant: Charles Guthrie Moyers ,  James Kermit Withrow ,  John Leonard Stephens

Inventor： Charles Guthrie Moyers ,  James Kermit Withrow ,  John Leonard Stephens

IPC: C07D493/04

CPC classification number: C07D493/04 ,  C07H1/06

Abstract: A process for the production of a refined dianhydrosugar-containing product is disclosed. The process includes controlled continuous crystallization of the dianhydrosugar-containing product to produce a solution saturated with the dianhydrosugar. The saturated solution is mechanically separated, for example by centrifugation, and the crystalline product is washed. The only solvent used is water. The dianhydrosugar-containing product is upgraded to at least 99.8% purity and recovery is 95% or greater.Recrystallization of the dianhydrosugar of 99.8% purity results in an ultra pure product containing at least 99.99% dianhydrosugar.

Abstract translation: 公开了一种生产精制含脱水糖的产品的方法。 该方法包括含二氢硫糖的产物的受控连续结晶以产生用二脱水糖饱和的溶液。 将饱和溶液机械分离，例如通过离心，并洗涤结晶产物。 所用的唯一溶剂是水。 含二氢蔗糖的产品升级至至少99.8％纯度，回收率为95％以上。 纯度为99.8％的二脱水糖的重结晶得到含有至少99.99％二脱水糖的超纯产品。