公开(公告)号：US07884245B2

公开(公告)日：2011-02-08

申请号：US11571399

申请日：2005-06-28

申请人： Kiyokazu Takaso ,  Katsumi Abe ,  Atsushi Takesue

发明人： Kiyokazu Takaso ,  Katsumi Abe ,  Atsushi Takesue

IPC分类号： C07C241/00 ,  C07C243/00

CPC分类号： C07C249/16 ,  C07C241/02 ,  C07C251/86 ,  C07C243/22

摘要： The present invention provides a process for producing a hydrazone compound represented by the general formula (5): which comprises a step of condensing a hydrazine compound represented by the general formula (3): with a carbonyl compound represented by the general formula (4): without taking the hydrazine compound out of a reactor. According to the invention, the target hydrazone compound can be obtained in high quality and in a high yield without taking the hydrazine compound out of the reactor at all, the hydrazine compound being a reaction intermediate which is structurally unstable and has a fear of influencing safety of workers owing to its toxicity (mutagenicity).

摘要翻译： 本发明提供由通式（5）表示的腙化合物的制造方法：其包括将通式（3）表示的肼化合物与通式（4）表示的羰基化合物缩合的工序， ：不将肼化合物从反应器中取出。 根据本发明，可以高质量，高收率地获得目标腙化合物，而不将肼化合物从反应器中完全除去，肼化合物是结构不稳定并且有害于影响安全性的反应中间体 的工人因其毒性（致突变性）而异。

公开(公告)号：US20080015387A1

公开(公告)日：2008-01-17

申请号：US11571399

申请日：2005-06-28

申请人： Kiyokazu Takaso ,  Katsumi Abe ,  Atsushi Takesue

发明人： Kiyokazu Takaso ,  Katsumi Abe ,  Atsushi Takesue

IPC分类号： C07C249/16

CPC分类号： C07C249/16 ,  C07C241/02 ,  C07C251/86 ,  C07C243/22

摘要： The present invention provides a process for producing a hydrazone compound represented by the general formula (5): which comprises a step of condensing a hydrazine compound represented by the general formula (3): with a carbonyl compound represented by the general formula (4): without taking the hydrazine compound out of a reactor According to the invention, the target hydrazone compound can be obtained in high quality and in a high yield without taking the hydrazine compound out of the reactor at all, the hydrazine compound being a reaction intermediate which is structurally unstable and has a fear of influencing safety of workers owing to its toxicity (mutagenicity).

摘要翻译： 本发明提供由通式（5）表示的腙化合物的制造方法：其包括将通式（3）表示的肼化合物与通式（4）表示的羰基化合物缩合的工序， ：不将肼化合物从反应器中取出根据本发明，可以以高品质和高产率获得目标腙化合物，而不将肼化合物从反应器中取出，肼化合物是反应中间体，其中 在结构上是不稳定的，并且由于其毒性（致突变性）而害怕影响工人的安全。