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公开(公告)号：US20100318064A1
公开(公告)日：2010-12-16
申请号：US12864723
申请日：2009-02-11
Applicant: Hugo George Derrick , Mathew David Frederick Stratton , Paul David Fielder
CPC classification number: A61M25/02 , A61B90/11 , A61L29/16 , A61L2300/00 , A61M25/0662 , Y10T29/49826
Abstract: A neurosurgical catheter is described for insertion into the brain parenchyma of a subject. The catheter comprises a flexible tube and has a stiff, non-porous, tip comprising at least one fluid delivery aperture. The stiff tip of the catheter may be mechanically stiffer than the flexible tube. The stiff tip may be provided by a stiff tube attached to the distal end of the flexible tube. The stiff tube may comprise a ceramic (e.g fused silica) and/or a metal. A kit comprising the catheter and a guide tube is also described. Methods of catheter implantation are also outlined.
Abstract translation: 描述了神经外科导管插入受试者的脑实质。 导管包括柔性管并且具有包含至少一个流体输送孔的刚性，无孔的尖端。 导管的刚性尖端可以比柔性管机械地更硬。 刚性尖端可以由附接到柔性管的远端的刚性管提供。 硬管可以包括陶瓷（例如熔融二氧化硅）和/或金属。 还描述了包括导管和引导管的套件。 还概述了导管植入的方法。
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公开(公告)号：US08974422B2
公开(公告)日：2015-03-10
申请号：US12312584
申请日：2007-11-21
Applicant: Steven Streatfield Gill , Paul David Fielder
Inventor： Steven Streatfield Gill , Paul David Fielder
CPC classification number: A61M39/0247 , A61M2039/025 , A61M2039/0264 , A61M2039/0276 , A61M2039/0282 , A61M2039/0285 , A61M2039/0291 , A61M2210/0693
Abstract: Apparatus for delivering therapeutic agents to the central nervous system of a subject is described. The apparatus comprises at least one intracranial catheter and a percutaneous access device. The percutaneous access device comprises a body having at least one extracorporeal surface and at least one subcutaneous surface, the body defining at least one port for connection to an implanted intracranial catheter. The port is accessible from the extracorporeal surface of the device, but is provided with a seal such as a rubber bung between the lumen of the port and the extracorporeal surface. The percutaneous access device may have more than two ports and/or a flange. A method of implanting the percutaneous access device is also described.
Abstract translation: 描述了将治疗剂递送到受试者的中枢神经系统的装置。 该装置包括至少一个颅内导管和经皮进入装置。 经皮进入装置包括具有至少一个体外表面和至少一个皮下表面的主体，该主体限定用于连接到植入的颅内导管的至少一个端口。 该端口可从装置的体外表面接近，但是在端口的内腔和体外表面之间设置有诸如橡胶塞之类的密封件。 经皮进入装置可具有多于两个的端口和/或凸缘。 还描述了植入经皮进入装置的方法。
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公开(公告)号：US20110009879A1
公开(公告)日：2011-01-13
申请号：US12733562
申请日：2008-10-06
Applicant: Hugo George Derrick , Paul David Fielder , Steven Streatfield Gill
Inventor： Hugo George Derrick , Paul David Fielder , Steven Streatfield Gill
IPC: A61B19/00
CPC classification number: A61B17/3403 , A61B17/3415 , A61B17/3423 , A61B90/11 , A61B2017/3407 , A61B2090/103
Abstract: A skull mount (50;150;170;200;300) is described that is attachable to a hole (60) formed in the skull. The skull mount (50;150;170;200;300) comprises an alignment guide (62;152;172;216;306) defining an alignment axis (22;210;312) along which neurosurgical instruments can be passed. The skull mount, when attached to a hole in a skull, is arranged such that it does not substantially protrude from the outermost surface of the skull and does not extend into the brain parenchyma. Also described is a neurosurgical alignment instrument (30,206) for aligning such a skull mount (50;150;170;200;300) that comprises an elongate shaft (32) and an element (34,36) protruding from the distal end of the elongate shaft (32) for engaging and aligning the alignment guide (62;152;172;216;306) of an associated skull mount (50;150;170;200;300). When the alignment instrument is engaged with a skull mount attached to a hole formed in the skull, the protruding element passes through the alignment guide of the skull mount and into the cortex of the subject's brain.
Abstract translation: 描述了可附接到形成在颅骨中的孔（60）的颅骨支座（50; 150; 170; 200; 300）。 颅骨支架（50; 150; 170; 200; 300）包括限定可以通过神经外科器械的对准轴线（22; 210; 312）的对准引导件（62; 152; 172; 216; 306） 颅骨安装件当附着在颅骨中的孔时被布置成使得其不会从颅骨的最外表面突出并且不延伸到脑实质中。 还描述了一种用于对准这样的颅骨支架（50; 150; 170; 200; 300）的神经外科对准仪器（30,206），其包括细长轴（32）和从所述头部远端突出的元件（34,36） 细长轴（32），用于接合和对准相关联的颅骨支架（50; 150; 170; 200; 300）的对准引导件（62; 152; 172; 216; 306）。 当对准仪器与附接到形成在颅骨中的孔的颅骨支架接合时，突出元件穿过颅骨支架的对准引导件并进入受试者大脑的皮层。
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4.发明申请公开(公告)号：US20100042070A1
公开(公告)日：2010-02-18
申请号：US12312584
申请日：2007-11-21
Applicant: Steven Streatfield Gill , Paul David Fielder
Inventor： Steven Streatfield Gill , Paul David Fielder
CPC classification number: A61M39/0247 , A61M2039/025 , A61M2039/0264 , A61M2039/0276 , A61M2039/0282 , A61M2039/0285 , A61M2039/0291 , A61M2210/0693
Abstract: Apparatus for delivering therapeutic agents to the central nervous system of a subject is described. The apparatus comprises at least one intracranial catheter and a percutaneous access device. The percutaneous access device comprises a body having at least one extracorporeal surface and at least one subcutaneous surface, the body defining at least one port for connection to an implanted intracranial catheter. The port is accessible from the extracorporeal surface of the device, but is provided with a seal such as a rubber bung between the lumen of the port and the extracorporeal surface. The percutaneous access device may have more than two ports and/or a flange. A method of implanting the percutaneous access device is also described.
Abstract translation: 描述了将治疗剂递送到受试者的中枢神经系统的装置。 该装置包括至少一个颅内导管和经皮进入装置。 经皮进入装置包括具有至少一个体外表面和至少一个皮下表面的主体，该主体限定用于连接到植入的颅内导管的至少一个端口。 该端口可从装置的体外表面接近，但是在端口的内腔和体外表面之间设置有诸如橡胶塞之类的密封件。 经皮进入装置可具有多于两个的端口和/或凸缘。 还描述了植入经皮进入装置的方法。
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