公开(公告)号：US06682722B2

公开(公告)日：2004-01-27

申请号：US10233880

申请日：2002-09-03

申请人： Satyanarayana Majeti ,  Niteen Vasant Bapat ,  Paula Denise Clymer ,  Elizabeth Ann Reno ,  William Michael Glandorf ,  Stephen Andras Kovacs

发明人： Satyanarayana Majeti ,  Niteen Vasant Bapat ,  Paula Denise Clymer ,  Elizabeth Ann Reno ,  William Michael Glandorf ,  Stephen Andras Kovacs

IPC分类号： A61K716

CPC分类号： A61Q11/02 ,  A61K8/24 ,  A61K8/8182 ,  A61Q11/00

摘要： Disclosed are oral care compositions and methods for overall cleaning, whitening and preventing, reducing or removing surface deposited stains on natural teeth and dental prosthesis, the compositions comprising in an orally acceptable carrier at least 0.1% by weight of a water-soluble or water-dispersible copolymer prepared by copolymerizing one or a mixture of vinyl pyrrolidone (VP) monomers with one or a mixture of C1-C19 alkyl carboxylic acid (AC) C2-C12 alkenyl ester monomers. Preferably, the compositions further comprise one or a mixture of other oral care agents selected from a water soluble alkali metal or ammonium tripolyphosphate in an amount at least about 0.5% by weight of the composition, an abrasive, preferably a precipitated silica abrasive, in an amount at least about 6% by weight of the composition and a bleaching agent in an amount at least about 0.1% by weight of the composition. This invention further relates to methods of cleaning, whitening and polishing natural teeth and dental prosthesis and of preventing, reducing or removing surface deposited stains from teeth by administering the present compositions.

摘要翻译： 公开了用于整体清洁，增白和预防，减少或去除天然牙齿和假牙上的表面沉积污渍的口腔护理组合物和方法，所述组合物在口腔可接受的载体中包含至少0.1重量％的水溶性或水溶性的， 通过将乙烯基吡咯烷酮（VP）单体的一种或混合物与C1-C19烷基羧酸（AC）C2-C12烯基酯单体的一种或混合物共聚制备的可分散共聚物。 优选地，组合物还包含选自水溶性碱金属或三聚磷酸铵的其它口腔护理剂的一种或其混合物，其量为组合物重量的至少约0.5％，研磨剂，优选沉淀二氧化硅研磨剂， 至少约6重量％的组合物和漂白剂，其量为组合物的至少约0.1重量％。 本发明还涉及通过施用本发明的组合物来清洁，增白和抛光天然牙齿和牙科假体以及防止，减少或去除牙齿表面沉积的污渍的方法。

公开(公告)号：US06696047B2

公开(公告)日：2004-02-24

申请号：US10218771

申请日：2002-08-14

申请人： Douglas Craig Scott ,  Paula Denise Clymer ,  Steven Carl Burgess ,  Christine Lula Johnson ,  James Carl Grimm

发明人： Douglas Craig Scott ,  Paula Denise Clymer ,  Steven Carl Burgess ,  Christine Lula Johnson ,  James Carl Grimm

IPC分类号： A61K716

CPC分类号： A61K8/34 ,  A61K8/20 ,  A61K8/33 ,  A61K8/35 ,  A61K8/42 ,  A61K8/498 ,  A61Q11/00

摘要： Stable topical oral compositions comprising at least a minimally effective amount of chlorite ion are disclosed, wherein the pH of the final composition is greater than 7, the composition is essentially free of chlorine dioxide, and the composition is stable against loss of chlorite for a period of at least one year under normal storage conditions at about 25° C. or for a period of 3 months under accelerated storage conditions at about 40° C. Preferably the compositions further comprise a flavor system, which is stable against degradation by chlorite. The compositions are formulated as therapeutic rinses, especially mouth rinses, as well as toothpastes, gels, tooth powders, chewing gums, mouth sprays, lozenges (including breath mints), dental implements (such as dental floss and tape), and pet care products.

摘要翻译： 公开了包含至少最低有效量的亚氯酸根离子的稳定的局部口服组合物，其中最终组合物的pH大于7，组合物基本上不含二氧化氯，并且组合物对于亚氯酸盐的损失是稳定的 在约25℃的正常储存条件下至少一年，或在加速储存条件下在约40℃下持续3个月。优选地，组合物还包含风味系统，其对于亚氯酸盐降解是稳定的。 将组合物配制成治疗性漂洗剂，特别是漱口剂，以及牙膏，凝胶，牙粉，口香糖，口腔喷雾剂，锭剂（包括呼吸薄荷），牙科用具（例如牙线和胶带）和宠物护理产品 。