专利检索 ap:"Saso Cemerski" 第 1 页

1.

发明授权
Combinations of PD-1 antagonists and benzo [b] thiophene STING agonists for cancer treatment 有权

公开(公告)号：US11312772B2

公开(公告)日：2022-04-26

申请号：US16635059

申请日：2018-07-30

申请人： Merck Sharp & Dohme Corp. , Saso Cemerski , Jared N. Cumming , Johnny E. Kopinja , Samanthi A. Perera , Benjamin Wesley Trotter , Archie Ngai-Chiu Tse

发明人： Saso Cemerski , Jared N. Cumming , Johnny E. Kopinja , Samanthi A. Perera , Benjamin Wesley Trotter , Archie Ngai-Chiu Tse

IPC分类号： A61P35/00 , A61K31/381 , A61K39/00 , C07K16/28

摘要： Therapeutic combinations that comprise at least one antagonist of the Programmed Death 1 receptor (PD-1) and at least one benzo[b]thiophene compound that activates the Stimulator of Interferon Genes (STING) pathway are disclosed herein. Also disclosed is the use of such therapeutic combinations for the treatment of cancers.

2.

发明申请
Combinations of PD-1 Antagonists and Benzo[b]thiophene STING Agonists for Cancer Treatment 有权

公开(公告)号：US20210130466A1

公开(公告)日：2021-05-06

申请号：US16635059

申请日：2018-07-30

申请人： Saso CEMERSKI , Jared N. CUMMING , Johnny E. KOPINJA , Samanthi A. PERERA , Benjamin Wesley TROTTER , Archie Ngai-Chiu TSE , Merck Sharp & Dohme Corp.

发明人： Saso CEMERSKI , Jared N. CUMMING , Johnny E. KOPINJA , Samanthi A. PERERA , Benjamin Wesley TROTTER , Archie Ngai-Chiu TSE

IPC分类号： C07K16/28 , A61P35/00 , A61K31/381

摘要： Therapeutic combinations that comprise at least one antagonist of the Programmed Death 1 receptor (PD-1) and at least one benzo[b]thiophene compound that activates the Stimulator of Interferon Genes (STING) pathway are disclosed herein. Also disclosed is the use of such therapeutic combinations for the treatment of cancers.