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公开(公告)号:US07396911B2
公开(公告)日:2008-07-08
申请号:US10614475
申请日:2003-07-07
IPC分类号: C07K14/00
CPC分类号: C07K14/523 , A61K38/00 , A61K39/3955 , A61K47/6813 , A61K47/6835 , C07K14/522 , C07K2319/00 , C07K2319/30 , A61K2300/00
摘要: This invention provides a chimeric DNA molecule comprising a sequence encoding a chemokine polypeptide covalently attached to a heterologous polypeptide, the encoded chimeric polypeptide, and uses thereof.
摘要翻译: 本发明提供了包含编码与异源多肽共价连接的趋化因子多肽的序列的嵌合DNA分子,编码的嵌合多肽及其用途。
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公开(公告)号:US06852508B1
公开(公告)日:2005-02-08
申请号:US09175713
申请日:1998-10-20
申请人: Stephen H. Herrmann , Zhijian Lu , John M. McCoy , Stephen L. Swanberg , Bruce Walker , Otto Yang
发明人: Stephen H. Herrmann , Zhijian Lu , John M. McCoy , Stephen L. Swanberg , Bruce Walker , Otto Yang
CPC分类号: C07K14/523 , A61K38/00 , A61K39/00 , A61K39/3955 , C07K14/521 , C07K14/522 , C07K2319/00 , A61K2300/00
摘要: This invention provides polynucleotides comprising sequences encoding amino-terminal-modified chemokines, the encoded amino-terminal-modified chemokines, and uses thereof.
摘要翻译: 本发明提供了包含编码氨基末端修饰趋化因子的序列的多核苷酸,编码的氨基末端修饰的趋化因子及其用途。
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公开(公告)号:US06730296B1
公开(公告)日:2004-05-04
申请号:US09467638
申请日:1999-12-20
IPC分类号: A61K4500
CPC分类号: C07K14/523 , A61K38/00 , A61K39/3955 , A61K47/6813 , A61K47/6835 , C07K14/522 , C07K2319/00 , C07K2319/30 , A61K2300/00
摘要: This invention provides a chimeric DNA molecule comprising a sequence encoding a chemokine polypeptide covalently attached to a heterologous polypeptide, the encoded chimeric polypeptide, and uses thereof.
摘要翻译: 本发明提供了包含编码与异源多肽共价连接的趋化因子多肽的序列的嵌合DNA分子,编码的嵌合多肽及其用途。
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公开(公告)号:US20090148507A1
公开(公告)日:2009-06-11
申请号:US12148143
申请日:2008-04-16
IPC分类号: A61K9/127 , A61K39/395 , A61K38/19 , C12N5/06
CPC分类号: C07K14/523 , A61K38/00 , A61K39/3955 , A61K47/6813 , A61K47/6835 , C07K14/522 , C07K2319/00 , C07K2319/30 , A61K2300/00
摘要: This invention provides a chimeric DNA molecule comprising a sequence encoding a chemokine polypeptide covalently attached to a heterologous polypeptide, the encoded chimeric polypeptide, and uses thereof.
摘要翻译: 本发明提供了包含编码与异源多肽共价连接的趋化因子多肽的序列的嵌合DNA分子,编码的嵌合多肽及其用途。
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公开(公告)号:US6100387A
公开(公告)日:2000-08-08
申请号:US808720
申请日:1997-02-28
IPC分类号: G01N33/53 , A61K38/00 , A61K39/395 , A61P29/00 , A61P31/18 , A61P37/02 , A61P37/04 , A61P43/00 , C07K14/52 , C07K16/24 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , G01N33/566 , C07H21/04 , C07K19/00
CPC分类号: C07K14/523 , A61K39/3955 , A61K47/48423 , A61K47/48507 , C07K14/522 , A61K38/00 , C07K2319/00 , C07K2319/30
摘要: This invention provides a chimeric DNA molecule comprising a sequence encoding a chemokine polypeptide covalently attached to a heterologous polypeptide, the encoded chimeric polypeptide, and uses thereof.
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