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1.发明授权
公开(公告)号：US4271084A
公开(公告)日：1981-06-02
申请号：US12151
申请日：1979-02-14
申请人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
发明人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
CPC分类号： A61K31/80 , C07F7/30 , C08G79/00 , C08J2203/14
摘要： Germanium-containing organic polymers are obtained by polymerizing 3-trichlorogermylpropionic acid obtained by reacting halogermanium-phosphoric acid complexes with acrylic acid. The polymers are markedly effective in mental diseases, disturbances in heart and vascular systems and are also effective against various cancers.
摘要翻译： 含锗的有机聚合物是通过将卤代 - 磷酸络合物与丙烯酸反应而获得的3-三氯锗烷基丙酸聚合而获得的。 这些聚合物在精神疾病，心脏和血管系统紊乱中显着有效，并且对各种癌症也有效。
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2.发明授权Germanium-containing organic polymer and its use in the treatment of allergic disease 失效含锗有机聚合物及其在治疗过敏性疾病中的应用
公开(公告)号：US4322402A
公开(公告)日：1982-03-30
申请号：US125929
申请日：1980-02-29
申请人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
发明人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
CPC分类号： A61K31/80 , C07F7/30 , C08G79/00 , C08J2203/14
摘要： Germanium-containing organic polymers are obtained by polymerizing 3-trichlorogermylpropionic acid obtained by reacting halogermanium-phosphoric acid complexes with acrylic acid. The polymers are markedly effective in treating allergenicities.
摘要翻译： 含锗的有机聚合物是通过将卤代 - 磷酸络合物与丙烯酸反应而获得的3-三氯锗烷基丙酸聚合而获得的。 聚合物在治疗变态反应方面显着有效。
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3.发明授权Germanium-containing organic polymer and its use in the treatment of pulmonary fibrosis 失效含锗有机聚合物及其在治疗肺纤维化中的应用
公开(公告)号：US4321273A
公开(公告)日：1982-03-23
申请号：US125947
申请日：1980-02-29
申请人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
发明人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
CPC分类号： C08G79/00 , A61K31/80 , C07F7/30 , C08J2203/14
摘要： Germanium-containing organic polymers are obtained by polymerizing 3-trichlorogermylpropionic acid obtained by reacting halogermanium-phosphoric acid complexes with acrylic acid. The polymers are markedly effective in treating pulmonary fibrosis.
摘要翻译： 含锗的有机聚合物是通过将卤代 - 磷酸络合物与丙烯酸反应而获得的3-三氯锗烷基丙酸聚合而获得的。 聚合物在治疗肺纤维化方面显着有效。
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4.发明授权Germanium-containing organic polymer and its use in the treatment of liver disorders 失效含锗有机聚合物及其在治疗肝脏疾病中的应用
公开(公告)号：US4309412A
公开(公告)日：1982-01-05
申请号：US125945
申请日：1980-02-29
申请人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setuso Tomisawa , Shigeru Toyoshima
发明人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setuso Tomisawa , Shigeru Toyoshima
CPC分类号： A61K31/80 , C07F7/30 , C08G79/00 , C08J2203/14
摘要： Germanium-containing organic polymers are obtained by polymerizing 3-trichlorogermylpropionic acid obtained by reacting halogermanium-phosphoric acid complexes with acrylic acid. The polymers are markedly effective in treating liver disorders.
摘要翻译： 含锗的有机聚合物是通过将卤代 - 磷酸络合物与丙烯酸反应而获得的3-三氯锗烷基丙酸聚合而获得的。 这些聚合物在治疗肝脏疾病中显着有效。
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5.发明授权Germanium-containing organic polymer and its use in the treatment of opthalmological disorders 失效含锗有机聚合物及其在治疗眼科疾病中的应用
公开(公告)号：US4296123A
公开(公告)日：1981-10-20
申请号：US125948
申请日：1980-02-29
申请人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
发明人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
CPC分类号： A61K31/80 , C07F7/30 , C08G79/00 , C08J2203/14
摘要： Germanium-containing organic polymers are obtained by polymerizing 3-trichlorogermylpropionic acid obtained by reacting halogermanium-phosphoric acid complexes with acrylic acid. The polymers are markedly effective in treating opthalmological disorders.
摘要翻译： 含锗的有机聚合物是通过将卤代 - 磷酸络合物与丙烯酸反应而获得的3-三氯锗烷基丙酸聚合而获得的。 聚合物在治疗眼科疾病中显着有效。
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6.发明授权
公开(公告)号：US4281015A
公开(公告)日：1981-07-28
申请号：US125876
申请日：1980-02-29
申请人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
发明人： Akira Ishikawa , Yukihito Ishida , Shiro Ikegami , Hiroshi Satoh , Ryuichi Sato , Setsuo Tomisawa , Shigeru Toyoshima
CPC分类号： A61K31/80 , C07F7/30 , C08G79/00 , C08J2203/14
摘要： Germanium-containing organic polymers are obtained by polymerizing 3-trichlorogermylpropionic acid obtained by reacting halogermanium-phosphoric acid complexes with acrylic acid. The polymers are markedly effective in treating psychoneurological disorders.
摘要翻译： 含锗的有机聚合物是通过将卤代 - 磷酸络合物与丙烯酸反应而获得的3-三氯锗烷基丙酸聚合而获得的。 聚合物在治疗精神病学疾病方面显着有效。
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7.发明授权
公开(公告)号：US4066678A
公开(公告)日：1978-01-03
申请号：US697568
申请日：1976-06-18
申请人： Ryuichi Sato , Akira Ishikawa , Yukihito Ishida , Hiroshi Sato , Setsuo Tomisawa , Shigeshi Toyoshima , Shiro Ikegami
发明人： Ryuichi Sato , Akira Ishikawa , Yukihito Ishida , Hiroshi Sato , Setsuo Tomisawa , Shigeshi Toyoshima , Shiro Ikegami
IPC分类号： A61K31/28 , A61P1/00 , A61P1/04 , A61P1/10 , A61P1/16 , A61P3/00 , A61P3/06 , A61P3/08 , A61P7/04 , A61P7/10 , A61P9/00 , A61P9/12 , A61P9/14 , A61P13/02 , A61P15/00 , A61P17/00 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/18 , A61P25/24 , A61P25/26 , A61P27/02 , A61P27/14 , A61P37/08 , A61P43/00 , C07F7/00 , C07F7/30
CPC分类号： C07F7/30 , C07F7/00 , Y10S514/826 , Y10S514/859 , Y10S514/863 , Y10S514/866 , Y10S514/869 , Y10S514/926 , Y10S514/927
摘要： Novel pharmacologically important organic germanium compounds (3-hydroxygermyl propionic acid salts) represented by the formula ##STR1## WHEREIN Met is a monovalent cation selected from the group consisting of Na, K, NH.sub.4, and NH.sub.2 (CH.sub.3).sub.2, or divalent cation selected from the group consisting of Ca and Mg, and wherein x is 1 when Met is a monovalent cation and x is 2 when Met is a divalent cation.These compounds possess valuable therapeutic properties for treating such physiological abnormalities as psychiatric and neurological disorders, metabolic disorder, cardivascular disorder, disorder of digestive organs, skin disease, allergic disease, Kidney dysfunction, hepatic dysfunction, obstetric and pediatric diseases, etc., and the process for preparing thereof.
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