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公开(公告)号：US20150141625A1
公开(公告)日：2015-05-21
申请号：US14600447
申请日：2015-01-20
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Doris Stoermer , George W. Griesgraber , James D. Mendoza , Jason D. Bonk
CPC classification number: C07K16/2815 , A61K31/4745 , A61K47/6803 , A61K47/6843 , A61K47/6849 , C07K16/2878 , C07K16/2887
Abstract: The present invention provides IRM conjugates that includes an IRM moiety and a second active moiety covalently linked to the IRM moiety in which the covalent link does not depend on UV irradiation.
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公开(公告)号：US09938275B2
公开(公告)日：2018-04-10
申请号：US15412850
申请日：2017-01-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Doris Stoermer , Joseph F. Dellaria, Jr. , David T. Amos , Bernhard M. Zimmermann , Luke T. Dressel , Jason D. Bonk , Matthew R. Radmer
IPC: C07D471/04 , C07D471/14
CPC classification number: C07D471/04 , A61K31/341 , A61K31/351 , A61K31/435 , A61K31/437 , A61K31/445 , C07D471/14
Abstract: Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
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3.发明申请公开(公告)号：US20140011777A1
公开(公告)日：2014-01-09
申请号：US14021197
申请日：2013-09-09
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Doris Stoermer , Joseph F. Dellaria, Jr. , David T. Amos , Bernhard M. Zimmermann , Luke T. Dressel , Jason D. Bonk
IPC: C07D471/04
CPC classification number: C07D471/04 , A61K31/341 , A61K31/351 , A61K31/435 , A61K31/437 , A61K31/445 , C07D471/14
Abstract: Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
Abstract translation: 咪唑并喹啉，吡啶和萘啶环体系（特别是喹啉，四氢喹啉，吡啶，[1,5]萘啶，[1,5]四氢萘并噻嗪）在1位被环状取代基取代的药物组合物 公开了制备这些化合物的方法，以及这些化合物作为免疫调节剂的用途，用于诱导动物中的细胞因子生物合成和治疗包括病毒和肿瘤疾病在内的疾病。
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4.发明授权公开(公告)号：US09550773B2
公开(公告)日：2017-01-24
申请号：US14684871
申请日：2015-04-13
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Doris Stoermer , Joseph F. Dellaria, Jr. , David T. Amos , Bernhard M. Zimmermann , Luke T. Dressel , Jason D. Bonk , Matthew R. Radmer
IPC: C07D471/04 , C07D471/14 , A61K31/341 , A61K31/351 , A61K31/437 , A61K31/445
CPC classification number: C07D471/04 , A61K31/341 , A61K31/351 , A61K31/435 , A61K31/437 , A61K31/445 , C07D471/14
Abstract: Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
Abstract translation: 咪唑并喹啉，吡啶和萘啶环体系（特别是喹啉，四氢喹啉，吡啶，[1,5]萘啶，[1,5]四氢萘并噻嗪）在1位被环状取代基取代的药物组合物 公开了制备这些化合物的方法，以及这些化合物作为免疫调节剂的用途，用于诱导动物中的细胞因子生物合成和治疗包括病毒和肿瘤疾病在内的疾病。
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Patent Agency Ranking
5.发明授权公开(公告)号：US09006264B2
公开(公告)日：2015-04-14
申请号：US14021197
申请日：2013-09-09
Applicant: 3M Innovative Properties Company
Inventor： Doris Stoermer , Joseph F. Dellaria, Jr. , David T. Amos , Bernhard M. Zimmermann , Luke T. Dressel , Jason D. Bonk
IPC: C07D471/04 , A61K31/341 , A61K31/351 , A61K31/437 , A61K31/445 , C07D471/14
CPC classification number: C07D471/04 , A61K31/341 , A61K31/351 , A61K31/435 , A61K31/437 , A61K31/445 , C07D471/14
Abstract: Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
Abstract translation: 咪唑并喹啉，吡啶和萘啶环体系（特别是喹啉，四氢喹啉，吡啶，[1,5]萘啶，[1,5]四氢萘并噻嗪）在1位被环状取代基取代的药物组合物 公开了制备这些化合物的方法，以及这些化合物作为免疫调节剂的用途，用于诱导动物中的细胞因子生物合成和治疗包括病毒和肿瘤疾病在内的疾病。
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公开(公告)号：US10472420B2
公开(公告)日：2019-11-12
申请号：US14600447
申请日：2015-01-20
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Doris Stoermer , George W. Griesgraber , James D. Mendoza , Jason D. Bonk
IPC: A61K39/44 , A61K39/385 , A61K47/48 , A61K31/4745 , C07K16/28 , A61K47/68
Abstract: The present invention provides IRM conjugates that includes an IRM moiety and a second active moiety covalently linked to the IRM moiety in which the covalent link does not depend on UV irradiation.
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公开(公告)号：US20180222906A1
公开(公告)日：2018-08-09
申请号：US15948594
申请日：2018-04-09
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Doris Stoermer , Joseph F. Dellaria, Jr. , David T. Amos , Bernhard M. Zimmermann , Luke T. Dressel , Jason D. Bonk , Matthew R. Radmer
IPC: C07D471/04 , C07D471/14
CPC classification number: C07D471/04 , A61K31/341 , A61K31/351 , A61K31/435 , A61K31/437 , A61K31/445 , C07D471/14
Abstract: Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
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公开(公告)号：US20170129891A1
公开(公告)日：2017-05-11
申请号：US15412850
申请日：2017-01-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Doris Stoermer , Joseph F. Dellaria, JR. , David T. Amos , Bernhard M. Zimmermann , Luke T. Dressel , Jason D. Bonk , Matthew R. Radmer
IPC: C07D471/04 , C07D471/14
CPC classification number: C07D471/04 , A61K31/341 , A61K31/351 , A61K31/435 , A61K31/437 , A61K31/445 , C07D471/14
Abstract: Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
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9.发明申请公开(公告)号：US20150218162A1
公开(公告)日：2015-08-06
申请号：US14684871
申请日：2015-04-13
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Doris Stoermer , Joseph F. Dellaria, JR. , David T. Amos , Bernhard M. Zimmermann , Luke T. Dressel , Jason D. Bonk , Matthew R. Radmer
IPC: C07D471/04 , C07D471/14
CPC classification number: C07D471/04 , A61K31/341 , A61K31/351 , A61K31/435 , A61K31/437 , A61K31/445 , C07D471/14
Abstract: Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
Abstract translation: 咪唑并喹啉，吡啶和萘啶环体系（特别是喹啉，四氢喹啉，吡啶，[1,5]萘啶，[1,5]四氢萘并噻嗪）在1位被环状取代基取代的药物组合物 公开了制备这些化合物的方法，以及这些化合物作为免疫调节剂的用途，用于诱导动物中的细胞因子生物合成和治疗包括病毒和肿瘤疾病在内的疾病。
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