公开(公告)号：US20140261930A1

公开(公告)日：2014-09-18

申请号：US13804148

申请日：2013-03-14

Applicant: ALLIANT TECHSYSTEMS INC.

Inventor： Stephen P. Velarde ,  Harold E. Johnston

IPC: C06B25/34

CPC classification number: C06B25/34 ,  C06B21/00 ,  C06B21/005 ,  C06B25/00

Abstract: A method of producing DEMN eutectic comprises reacting a reactant mixture comprising ethylenediamine and diethylenetriamine with aqueous nitric acid to form a reaction mixture comprising diethylentriamine trinitrate and ethylenediamine dinitrate. The reaction mixture is combined with methylnitroguanidine and nitroguanidine to form an aqueous slurry. Water is removed from the aqueous slurry. A method of producing an energetic composition, and a system for producing DEMN eutectic are also described.

Abstract translation: 制备DEMN共晶体的方法包括使含有乙二胺和二亚乙基三胺的反应物混合物与硝酸水溶液反应，形成包含二硝基三硝酸三乙酯和二乙二胺二硝酸酯的反应混合物。 将反应混合物与甲基硝基胍和硝基胍组合以形成含水浆液。 从含水浆液中除去水。 还描述了生产能量组合物的方法和用于生产DEMN共晶体的系统。

公开(公告)号：US20130309324A1

公开(公告)日：2013-11-21

申请号：US13951720

申请日：2013-07-26

Applicant: Lynn M. Oehler ,  RadioRx, Inc., c/o Interwest Venture Partners ,  Alliant Techsystems Inc.

Inventor： Mark D. Bednarski ,  Susan Knox ,  Louis F. Cannizzo ,  Kristin F. Warner ,  Robert B. Wardle ,  Stephen P. Velarde ,  Shoucheng Ning

IPC: C07D303/22 ,  A61K45/06 ,  A61K31/336

CPC classification number: C07D303/22 ,  A61K31/21 ,  A61K31/336 ,  A61K31/38 ,  A61K31/395 ,  A61K45/06

Abstract: The present invention provides O-nitro compounds, pharmaceutical compositions of O-nitro compounds and methods of using O-nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cell proliferation, such as cancer, inflammation, cardiovascular disease and autoimmune disease.

Abstract translation: 本发明提供O-硝基化合物，O-硝基化合物的药物组合物和使用O-硝基化合物和/或其药物组合物的方法来治疗或预防以异常细胞增殖为特征的疾病或病症，例如癌症，炎症，心血管 疾病和自身免疫性疾病。