公开(公告)号：US20210179723A1

公开(公告)日：2021-06-17

申请号：US17111453

申请日：2020-12-03

Applicant: AMGEN INC.

Inventor： Thomas C. BOONE ,  David W. BRANKOW ,  Colin V. GEGG, Jr. ,  Shaw-Fen Sylvia HU ,  Chadwick T. KING ,  Hsieng Sen LU ,  Licheng SHI ,  Cen XU

IPC: C07K16/28 ,  A61K39/395

Abstract: Antigen binding proteins that bind to human CGRP receptor (CGRP R) are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of CGRP R to CGRP, and are useful in a number of CGRP R related disorders, including the treatment and/or prevention of migraine headaches.